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CITY CHILDREN'S HOSPITAL № 1: HISTORICAL SKETCH OF DEVELOPMENT OF THE CITY NURSERY OF HOSPITAL № 1 OF KAZAN

MARINA V. POTAPOVA, ELENA A. KUZMINA

Abstract. The short sketch of history of development of city children’s hospital № 1 of Kazan is given in article. Posveshchen to the 30th lithium of stationary service «City Children’s Hospital № 1» of Kazan

Key words: city children’s hospital № 1 of Kazan, medicine history.

 

CHILDREN'S CITY HOSPITAL № 1 OF KAZAN AND THE DEPARTMENT OF PEDIATRICS AND NEONATOLOGY KSMA: A HISTORY OF SOLIDARITY

ASIA I. SAFINA, ILDOUS Y. LUTFULLIN

Abstract. The article provides a brief sketch of the history of the joint development of the department of pediatrics and neonatology Kazan State Medical Academy and the Children’s City Hospital № 1 of Kazan.

Key words: Department of Pediatrics and Neonatology Kazan State Medical Academy, Children’s City Hospital № 1 in Kazan, the history of medicine.

 

© Р.А. Файзуллина, В.В. Софронов, Т.Г. Маланичева, Н.В. Зиатдинова, 2013

УДК 614.21(09)(470.41-25):378.4

ИСТОРИЯ КАФЕДРЫ (КУРСА) ДЕТСКИХ БОЛЕЗНЕЙ ЛЕЧЕБНОГО ФАКУЛЬТЕТА КАЗАНСКОГО ГОСУДАРСТВЕННОГО МЕДИЦИНСКОГО УНИВЕРСИТЕТА И ЕЕ РОЛЬ В ОРГАНИЗАЦИИ ОТДЕЛЕНИЯ ПАТОЛОГИИ НОВОРОЖДЕННЫХ ГДБ № 1 Г. КАЗАНИ

РЕЗЕДА АХАТОВНА ФАЙЗУЛЛИНА, докт. мед. наук, доцент, зав. кафедрой пропедевтики детских болезней и факультетской педиатрии с курсом детских болезней лечебного факультета ГБОУ ВПО «Казанский государственный медицинский университет», Казань, Россия, e-mail: rector@kgmu.kcn.ru

ВАЛЕРИЙ ВИКТОРОВИЧ СОФРОНОВ, докт. мед. наук, профессор кафедры пропедевтики детских болезней и факультетской педиатрии с курсом детских болезней лечебного факультета ГБОУ ВПО «Казанский государственный медицинский университет», Казань, Россия, e-mail: rector@kgmu.kcn.ru

ТАТЬЯНА ГЕННАДЬЕВНА МАЛАНИЧЕВА, докт. мед. наук, профессор кафедры пропедевтики детских болезней и факультетской педиатрии с курсом детских болезней лечебного факультета ГБОУ ВПО «Казанский государственный медицинский университет», Казань, Россия, e-mail: rector@kgmu.kcn.ru

НЕЛЛИ ВАЛЕНТИНОВНА ЗИАТДИНОВА, канд. мед. наук, доцент кафедры пропедевтики детских болезней и факультетской педиатрии с курсом детских болезней лечебного факультета ГБОУ ВПО «Казанский государственный медицинский университет», Казань, Россия, e-mail: rector@kgmu.kcn.ru

Реферат. В статье приводится исторический очерк развития и становления кафедры пропедевтики детских болезней и факультетской педиатрии с курсом детских болезней лечебного факультета КГМУ МЗ РТ, а также ее роль в организации отделения патологии новорожденных и недоношенных детей городской детской больницы № 1 г. Казани.

Ключевые слова: кафедра пропедевтики детских болезней, история медицины, Казанский медицинский уни­верситет.

 

GENDER IDENTITY — A BASIS FOR EARLY SURGICAL CORRECTION OF CHILDREN WITH DISIRDER OF SEX DEVELOPMENT

NAIL R. AKRAMOV, ILSIYAR A. AKRAMOVA, AYDAR K. ZAKIROV, AIDA F. MINULLINA

Abstract. The article is devoted to the formation of gender identity in children with abnormal sex. Age-specifc gender identity was considered. There wasmodern understanding of cognitive, affective and evaluative, and behavioral components of the disorders was shown in the structure of sexual gender identity in childhood, depending on the formation of genital malformations of child. Detected psychological factors were the basis for recommendations to early surgical correction in children with disorder of sex development.

Key words: gender, gender identity, impaired formation of gender, surgical correction in children with disorder of sex development.

 

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EFFICIENCY OF ANTIEPILEPTIC DRUGS OF NEW GENERATION IN THERAPY OF CRYPTOGENIC AND SYMPTOMATIC FOCAL FORMS OF EPILEPSY IN CHILDREN

SVETLANA N. SIVKOVA, FANIYA M. ZAYKOVA

Abstract. Purpose. Comparison of the clinical effciency of antiepileptic drugs of new generation — topiramate and lamotrigine — in treatment of symptomatic and cryptogenic focal forms of epilepsy in children. Material and methods. 2 groups of patients were included in research, aged from 2 to 17 years old, on 31 person in each group with symptomatic and cryptogenic focal forms of epilepsy. 1 group of patients were treated by topiramate in dozes from 56 up to 500 mg/day, from 2,8 mg/kg/day up to 17 mg/kg/day (on the average 6,6 mg/kg/day). Patients of the second group received therapy by lamotrigine in dozes from 25 mg/day up to 250 mg/day, from 0,5 mg/kg/day up to 6 mg/kg/day (on the average 3,6 mg/ kg/day). Treatment was in monotherapy and in combinations with others antiepileptic grugs. Results. Seizures freedom was achieved in 26% of patients in each groups. Reduction of seizures freqency more than 50% was observed in 61 % cases in topiramate group and in 45% of cases in lamotrigine group. Aggravation of myoclonic seizures was registered in 1 (3%) patient, used topiramate and in 2 (6%) patients used lamotrigine. Conclusion. Topiramate and lamotrigine have shown high clinical effciency in treatment symptomatic and cryptogenic focal forms of epilepsy in children.

Key words: focal epilepsy, treatment, children, topiramate, lamotrigine.

 

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FEATURE LONG-CHAIN POLYUNSATURATED FATTY ACIDS NEWBORN AT RISK AND THEIR MOTHERS

VALERY V. SOFRONOV, EVGENIA A. AGAFONOVA, DIANA .I. SHEGUROVA, OLGA V. SHARIPOVA, ANNA A. BABINTSEVA, NELLY A. ABRAMZON

Аbstract .This article analyzes the content of LCPUFA: arachidonic acid (AA) and docosahexaenoic acid (DHA) in the serum of newborns and their mothers. Determination of fatty acids was carried out by gas chromatography method. Found that for miscarriage occurs on a 3-fold reduction of DHA with a parallel increase in the content of AA. Transplacental transport of fatty acids is biased towards preferential accumulation in the body of the fetus \ newborn AK.

Key words: newborn baby, new mother, arachidonic acid, docosahexaenoic acid, gas chromatography.

 

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MEDICINES OF PYRIMIDINE'S ROW

IN EXPERIMENTAL AND CLINICAL RESEARCHES

AIDA H. IZMAYLOVA, DILYARA H. SHAKIROVA, ALEXANDER G. IZMAYLOV

Abstract. In the review of literature there is the analysis of the publications devoted to researches on application of medicines of a pyrimidine’s row in experiments and clinic. The received results testify to a wide range of action of this class of medicines, the basic ones are stimulation of regenerative processes, immunotropic and anti-infammatory actions. Now among preparations of the pyrimidine’s row there is Xymedon, developed by the experts in Kazan. Key words: pyrimidine’s derivatives, Xymedon, methyluracilum, oxymethyluracilum, anti-infammatory, antioxidant and immunostimulating actions.

 

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XYMEDON EXPERIENCE OF THERAPY IN COMPLEX CAP IN SCHOOL — AGE CHILDREN

IRINA V. SITDIKOVA, FARIDA S. PIROGOVA, AIDA H. IZMAILOVA, OLGA I. PIKUZA, ELMIRA D. KASHAFOVA, ILDARIA H.VALEEVA, INNA V. RUSAKOVA

Abstract. The purpose of the study — to examine the effectiveness of xymedon in the treatment of community-acquired pneumonia in children of school age. Material and methods. We observed 103 children aged 7 to 17 years, who were divided into 3 groups: group 1 — in addition to conventional therapy received xymedon (37 children ), the group 2 — in the complex therapy was part metiluratsil (34 children ), the group comparison — conventional therapy (32 children ) . The effectiveness of treatment was assessed by clinical parameters , indicators of the general analysis of blood, the level of malondialdehyde and total antioxidant activity in saliva. Results and discussion. It was determined that the number of children at one clinical and laboratory parameters to normalize earlier than patients of other study groups. Conclusion. Appointment of domestic preparation of pyrimidine series xymedon in the complex therapy of community-acquired pneumonia in children of school age accelerates the timing of clinical recovery. Keywords: xymedon, metiluratsil, community-acquired pneumonia, children of school age.

 

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4.   Pikuza, A.H. Klinicheskoe znachenie mestnyh pokazatelej perekisnogo okislenija lipidov i antioksidantnoj zashhity u bol'nyh posle jekstrakcii katarakty / A.H. Pikuza, M.V. Kuznecova, L.E. Ziganshina, I.H. Valeeva // Vestnik oftal'mologii. — 2008. — № 1. — S.19—22.
5.   Pikuza, O.I. Osobennosti sostojanija kletochnyh membran pri razlichnyh kliniko-morfologicheskih variantah vnebol'nichnyh pnevmonij u detej-shkol'nikov / O.I. Pi-kuza, A.M. Zakirova, H.M. Vahitov [i dr.] // Pediatrija. — 2013. — № 3. — S.18—20.
6.   Tereshhenko, V.Ju. Ispol'zovanie ksimedona v lechenii hronicheskogo osteomielita / V.Ju. Tereshhenko, K.V. Malyshev // Farmakologija i toksikologija biologicheski aktivnyh veshhestv. — 1996. — № 2. — S.132.
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A CASE OF ULCERATIVE COLITIS WITH THE PREVALENCE

OF EXTRACOLONIC MANIFESTATIONS — SPONDYLOARTHRITIS

AND INFLAMMATORY PSEUDOTUMOR

VALERY Y. SHAPIRO, ILDOUS Y. LUTFULLIN, SVETLANA Y. YUMASHEVA, ASIA I. SAFINA

Abstract. The article is devoted to extracolonic manifestations of ulcerative colitis. A case of ulcerative colitis with

spondiloarthritis and infammatory pseudotumor is given.

Key words: ulcerative colitis, spondiloarthritis, infammatory pseudotumor.

 

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2. Rekomendacii po diagnostiki i lecheniju vzroslyh bol'nyh jazvennym kolitom, 2013 g. / V.T. Ivashkin, Ju.A. Shelygin, D.I. Abdulganieva [i dr.] — URL: http://obshhestvo-hirurgov.rf/stranica-pravlenija/kliniches-kie-rekomendaci/koloproktologija/klinicheskie-rekomendaci-po-diagnostike-i-lecheniyu-vzroslyh-bolnyh-jazvenym-koli-tom.html svobodnyj
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5.   Spontaneous regression of hepatic infammatory pseudo-tumor with primary biliary cirrhosis: case report and literature review / H. Koide, K. Sato, T. Fukusato, [et al.] // World J. Gastroenterol. — 2006. — № 12 (10). — P.1645— 1648.
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9.   Infammatory pseudotumor of the spleen. Morphological, radiological, immunophenotypic, and ultrastructural features / B.I. Dalal, H. Greenberg, G.E. Quinonez, J.C. Gough // Arch. Pathol. Lab. Med. — 1991. — № 5 (10). — P.1062—1064.
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COMPARATIVE OBSERVATION OF CHILDREN WITH ROP FOR YEARS 2011—2012 GAUSE «GDB № 1» OF KAZAN

MARINA V. POTAPOVA, GULSINA М. KHUZEYEVA, INDIRA I. SHAMSUTDINOVA, ELENA A.KUZMINA, OLGA V. SHARIPOVA

Abstract. The article covers the problem of increasing the number of premature infants with a violation of the cardiovascular system of the retina. In this paper the problem is studied on the materials of GAUSE «Children’s hospital № 1» of Kazan. Structure of the study was built on the consistent study of the data grouped in the table on certain grounds and analysis in mutual communication and causation. The analysis has revealed the problem is not formally refected in the similar tables, analyzed in isolation, namely the increase in the number of premature faster than the growth of the birth rate, the proportion of children with severe degree of retinopathy, a similar situation is observed with the degree of prematurity. Key words: Retinopathy of prematurity, operative intervention, the negative trend.

 

LiteRatURa
1.   Tereshhenko, A.V. Rannjaja diagnostika i monitoring retinopatii nedonoshennyh / A.V. Tereshhenko, Ju.A. Belyj, I.G. Trifanenkova; pod red. H.P. Tahchidi. — Kaluga, 2008. — 84 s.: il.
2.   Sajdasheva, Je.I. Izbrannye lekcii po neonatal'noj oftal'mologii / Je.I. Sajdasheva, E.E. Somov, I.V. Fomina. — SPb.: Izdatel'stvo «Nestor-Istorija», 2006. — 272 s.: il.

 

A CASE OF LIVER ABSCESS OF A NEWBORN BABY

KH. S. KHAERTYNOV, O. V. SHARIPOVA, A. A. PODSHIVALIN

Abstract. The article presents a case of liver abscess of a newborn baby. Considered the basic clinical and laboratory sings of liver abscess and risk factors for its development. Key words: newborn, liver abscess.

 

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TREATMENT OF OSTEOPOROSIS IN PATIENTS WITH CONGENITAL DEFICIENCY OF VITAMIN K COMBINED-DEPENDED COAGULATION FACTORS (II, VII, IX, X, PROTEIN C AND PROTEIN S)

VALERI J. SHAPIRO, GULIA A. KHAMZINA, ASIA I. SAFINA, ASYA V. GALEEVA, ILDUS I. LUTFULLI.

Abstract. Article is devoted to treatment osteoporosis of in congenital defciency of vitamin of K-dependent factors of a coagulation. The disease is connected to congenital defciency of gamma carboxylase or enzyme vitamin K epokside reductaze. The lack of gamma carboxylation of osteocalcin — one of cementing factors — results in damage of linking of collagen with a mineral component of a bone. A case of congenital defciency of vitamin K combined — depended coagulation factors is given. Key words: vitamin K-dependent clotting factor defciency, osteoporosis, gamma-carboxylation of osteocalcin.

 

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NEW HORIZONS IN MOTHER CARE

AND OBSERVATION OF PREMATURE CHILDREN

IN THE CHILDREN'S CITY HOSPITAL № 1

ELENA V. VOLYANYUK, GULSINA M. KHUZEEVA, ЕLENA A. KUZMINA, OLGA V. SHARIPOVA

Abstract. This article presents the main problems of premature infants discharged from the neonatal pathology department of Children’s Hospital № 1, the frst results of the center catamnesis premature babies. Key words: preterm infants, follow-up, rehabilitation activities.

 

LiteRatURa
1.   Posledujushhee nabljudenie nedonoshennyh v klinike razvitija Universiteta Jemori (SShA) / A.I. Safina, I.Ja. Lut-fullin, N.L. Rybkina [i dr.] // Vestnik sovremennoj klinicheskoj mediciny. — 2013. — T. 6. — S.86—90.
2.   Jacyk, G.V. Problemy i perspektivy vyhazhivanija novorozhdennyh s jekstremal'no nizkoj massoj tela / G.V. Jacyk // Vestnik RAMN. — 2008. — № 12. — S.41—44.
3.   Jacyk, G.V. Vyhazhivanie i rannjaja reabilitacija detej / G.V. Jacyk, E.P. Bombardirova, O.V. Tresorukova // Lechashhij vrach. — 2007. — № 7. — S.23—27.
4.   Sizun, J. Erly developmental care for preterm babies: a call for more research/ J. Sizun, B. Westrap // Arch. Dis. Child. Fetal and neonatal edition. — 2004. — Vol. 89. — R.384—388.

 

PROGNOSTIC SIGNIFICANCE OF THE NUCLEAR DNA OF LYMPHOCYTES AND EXTRACELLULAR DNA IN NEWBORNS WITH DIFFERENT GESTATIONAL AGE

DIANA I. SHEGUROVA, VALERY V. SOFRONOV, SERGEY A. LUBIN, ELENA V. MAVRINA

Abstract. Article is devoted to studying of features of parameters of nuclear and extracellular DNA at newborns of various gestational age in the early neonatal period for determination of features of formation of adaptic processes and the prognostic importance. Key words: nuclear DNA, extracellular DNA, newborns.

 

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