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Original Articles

Respiratory sarcoidosis in military servants. D.N. Antipushina, A.A. Zaytsev

Efficiency of dabigatran etexilatein treatment of warfarin-induced thrombosis after hip arthroplasty. L.V. Borisova, S.N. Didichenko, A.V. Orlova

Monitoring the quality of life using a questionnaire SF-36 as a leading indicator prediction epidemiological situation tuberculosis. A.N. Danilov

Result of total dissociation of gastroesophageal collector in patients with portal hypertension. F.G. Nazyrov, A.V. Devyatov, A.Kh. Babadzhanov, Zh.D. Zhamilov

Practice orthopedic treatment of patients with maxillofacial pathology. A.I. Raff

Nature association of polymorphism gene apolipoprotein B-100 with lipid metabolism in patients with cholelithiasis. A.A. Sagdatova, A.Kh. Nurgalieva, E.K. Khusnutdinova, Sh.Z. Zagidullin

Depression in neurological practice (in cases of pain syndromes and stroke). D.R.Teregulova, M.A.Kutlubaev, L.R. Akhmadeeva

Lipid metabolism in patients with coronary artery disease and comorbidities depending on stenosis of the left main coronary artery. G.Z. Khalimova, A.S. Galyavich, M.V. Panasyuk

Results of using magnetic-infrared-laser therapy in complex treatment of patients with new-onset destructive pulmonary tuberculosis. A.L. Khanin, G.V. Pilnik, G.L. Nicotina

Organization of Healthcare

State disability population city of Kazan 1995—2011 yy. N.N. Shamsiyarov, A.N. Galiullin

Help for Practitioner

New tool and method of tying surgical units in laparoscopic gynecological surgery. O.V. Galimov, E.Yu. Dmitrieva, V.O. Khanov, O.A. Filippova

The complex approach in treatment of children with congenital labium and palate clefts in Tatarstan Republic practice. P.V. Tokarev, A.V. Shulaev, L.V. Plaksina

Reviews

Closed heart injury on the prehospital. A.I. Abdrakh-manova, N.B. Amirov, N.A. Tsibulkin

Cardioprotective effect of ischemic conditioning. A.Z. Sharafeev, V.A. Bayazitova, A.R. Iskhakova

Correspondence

Electronic cigarettes— «way of smoking» or quit smoking devices? Commentary article on V.D. Mendelevich. P.K. Yablonsky, O.A. Sukhovskaya

When the issue was in press

Publication Ethics and Editorial Policy N.B.Amirov, A.A. Vizel, M.A. Daminova, R.N. Amirova, R.I. Shaymuratov

Original articles

Respiratory sarcoidosis in military servants

Diana N. Antipushina, Senior registrar of the Department of pulmonary of the Main Military Clinical Hospital of named after acad. N.N. Burdenko, Moscow, Russia, tel. 8-499-263-53-20, e-mail: dndoc@bk.ru

Andrey A. Zaytsev, Doctor of Medical Sciece, Chief of the Department of pulmonary of the Main Military Clinical Hospital of named after acad. N.N. Burdenko, Moscow, Russia, tel. 8-499-263-10-47, e-mail: a-zaicev@yandex.ru

Abstract. Objective. To study the clinical features and quality of life and to determine risk factors for the recurrent sarcoidosis among the military servants. Material and methods. The study involved 124 patients, mean age (31,8±9,9) years. The clinical, radiological and laboratory data have been examined, the quality of life has been analysed using a SHQ questionnaire, the correlation analysis was performed. Results and discussion. It was found that 85,5% of military personnel had respiratory sarcoidosis of stages I and II, asymptomatic disease course prevailed (72% of cases). Morphological verification of the sarcoidosis was most frequently performed by mediastinoscopy with biopsy of intrathoracic lymph nodes (36,3%); the percentage of traumatic surgery was 6,2%. The quality of life of military personnel with sarcoidosis was reduced according to the scales of daily, physical and emotional functioning up to 56,7, 80 to 70% of cases respectively. The factors associated with recurrent sarcoidosis were: age > 35 years (p=0,039, OR — 5,03); the presence of clinical manifestations (p=0,011, OR — 3,47) (cough, weakness, shortness of breath); FVC < 85% of predicted values (p=0,029, OR — 4,23); systemic corticosteroids in past history (p=0,004, OR — 11,43). We designed predictive scale, the practical value of which amounted to 82,4%, sensitivity 58,8% and specificity of 88,2%. Conclusion. The findings suggests the need to implement a common algorithm for the management of military personnel sarcoidosis, including the widespread use of minimally invasive methods of morphological verification, the balanced approach to the prescription of systemic steroids. Despite the prevalence of asymptomatic forms of the disease, the quality of life of patients with sarcoidosis is decreased. The risk factors for relapse are: age > 35 years, the presence of clinical manifestations, FVC < 85%, SCS treatment history. There have been designed predictive scale for recurrent course of sarcoidosis in young patients which has a high predictive value.

Key words: sarcoidosis, the military, risk factors of the recurrent course, the scale of the forecast the relapse of sarcoidosis.

 

References

1. Diagnostika i lechenie sarkoidoza: rezyume federal'nyh soglasitel'nyh klinicheskih rekomendacii. Klassifikaciya, etiopatogenez, klinika: ch. 1 [Diagnosis and treatment of sarcoidosis: a summary of federal consensus clinical guidelines. Classification, etiopathogenesis, clinical: part 1] / A.G. Chuchalin, A.A. Vizel', M.M. Il'kovich [i dr.] // Vestnik sovremennoi klinicheskoi mediciny [Bulletin of contemporary clinical medicine]. — 2014. — T. 7, vyp. 4. — S.62—70.
2. Diagnostika i lechenie sarkoidoza: rezyume federal'nyh soglasitel'nyh klinicheskih rekomendacii. Diagnostika, lechenie, prognoz: ch. 2 [Diagnosis and treatment of sarcoidosis: a summary of federal consensus clinical guidelines. Diagnosis, treatment, prognosis: part 2] / A.G. Chuchalin, A.A. Vizel', M.M. Il'kovich [i dr.] // Vestnik sovremennoi klinicheskoi mediciny [Bulletin of contemporary clinical medicine]. — 2014. — T. 7, vyp. 5. — S.73—81.
3. ATS/ERS/WASOG statement on sarcoidosis. American Thoracic Society / G.W. Hunninghake, U. Costabel, M. Ando [et al.]; European Respiratory Society/World Association of Sarcoidosis and other Granulomatous Disorders // Sarcoidosis Vasc. Diffuse Lung Dis. — 1999. — Vol. 16, № 2. — P.149—173.
4. James, D. Epidemiology of sarcoidosis / D. James // Sarcoidosis. — 1992. — Vol. 9, № 2. — R.79—87.
5. Jajosky, P. Sarcoidosis diagnoses among U.S. military personnel: trends and ship assignment associations / P. Jajosky // Amer. J. Prev. J. Med. — 1998. — Vol. 14, № 3 — P.176—183.
6. Diagnostika i lechenie pacientov s sarkoidozom v mnogoprofil'nom voennom stacionare. Predvaritel'nye itogi [Diagnosis and treatment of patients with sarcoidosis in versatile military hospital. Preliminary results] / A.A. Zaicev, D.N. Antipushina, I.V. Sivokozov, S.A. Chernov // Voenno-medicinskii zhurnal [Military Medical Journal]. — 2012. — № 9. — S.35—41.

 

 

Efficiency of dabigatran etexilate in treatment of warfarin-induced thrombosis after hip arthroplasty 

Ludmila v. Borisova, clinical pharmacologist of FSBI «The Federal centre of traumatology, orthopedics and arthroplasty» of russian Ministry of Health, cheboksary, russia, tel. +7(8352)-30-57-81, e-mail: lborisova@orthoscheb.com

Svetlana N. Didichenko, general practitioner of FSBI «The Federal centre of traumatology, orthopedics and arthroplasty» of Russian Ministry of Health, Cheboksary, Russia, tel. +7(8352)-30-57-05, e-mail: mishina@orthoscheb.com

Alena v. Orlova, Candidate of Medical Science, doctor of metodical department of FSBI «The Federal centre of traumatology, orthopedics and arthroplasty» of russian Ministry of Health, cheboksary, russia, tel. +7(8352) 30-57-08, e-mail: aorlova@orthoscheb.com

Abstract. The goal is to show a treatment option with dabigatran etexilate for warfarin-induced thrombosis after hip replacement arthroplasty. Material and methods. Clinical observation. Results and discussion. The main reason for the development of deep vein thrombosis of operated lower limb after hip replacement arthroplasty was anticoagulant warfarin prophylaxis against the backdrop of the low level of protein C. Therefore the inactivation of vitamin-K dependent coagulation factors (Va и VIIIa) responsible for the production of thrombin was disturbed, which led to its excessive production and consequent increase in thrombogenicity. Long-term anticoagulant therapy (during 6 month) with dabigatran-etexilate helped to achieve high positive clinical results. Conclusions. In order to prevent the development of thrombotic complications in patients with thrombotic history, before prescribing warfarin is expedient to determine the level of physiological anticoagulants in the blood including the level of protein C.

Key words: warfarin-induced thrombosis, joint replacement, dabigatran etexilate, protein C.

 

References

1. Vasil'ev, S.A. Trombozy i trombofilii: klassifikaciya, diagnostika, lechenie, profilaktika [Thrombosis and thrombophilia: classification, diagnosis, treatment, prevention] / S.A. Vasil'ev, V.L. Vinogradov, A.N. Smirnov [i dr.] // Russkii medicinskii zhurnal [Russian medical journal]. — 2013. — № 17. — S.896.
2. Chan, Y.C.2. Warfarin induced skin necrosis / Y.C. Chan, D. Valentini, A.O. Mansfield, G. Stensby // Br. J. Surg. — 2000. — Vol. 87(3). — P.266—272.
3. Essex, D.W.3. Late-onset warfarin- induced skin necrosis: case report and review of the literature / D.W. Essex, S.S. Wynn, D.K. Jin // Am. J. Hematol. — 1998. — Vol. 57(3). — P.233—237.
4. Geerts, W.H.4. Prevention of venous thromboembolism: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy / W.H. Geerts, G.F. Pineo, J.A. Heit [et al.] // Chest. — 2004. — Vol. 126 (suppl. 3). — P.338S—400S.
5. Haas, S.5. Deep vein thrombosis. Beyond the operating table / S. Haas // Orthopedics. — 2000. — Vol. 23, № 6. — P.629—632.
6. Heit, J.A. 6.    Prevention of venous thromboembolism: Sixth American college of chest physiciane consensus conference on antithrombotic therapy / J.A. Heit, G.P. Clagett // Chest. — 2001. — Vol. 119. — P.1325—1755.
7. Ikezoe, T. Trombomodulin/activated protein C system in septic disseminated intravascular coagulation / T. Ikezoe // J. Intensive Care. — 2015. — Vol. 3(1). — URL: 1.doi: 10.1186/s40560-014-0050-7.eCollection 2015
8. Irwin, R.S. Warfarin induced skin necrosis / R.S. Irwin, J.M. Rippe // Irwin and Rippe is Intensive Care Medicine. — 6th ed. — Philadelphia: Lippincott Williams, 2007. — P.2267.
9. Warkentin, T.E. Multicentric warfarin-induced skin necrosis complicating heparin-induced thrombocytopenia / T.E. Warkentin, W.M. Sikov, D.P. Lillicrap // Am. J. Hematol. — 1999. — Vol. 62(1). — P.44—48.
10. White, R.H. Incidence and time course of thromboembolic outcomes following total hip or knee arthroplasty / R.H. White, P.S. Romano, H. Zhou [et al.] // Arch. Intern. Med. — 1998. — Vol. 158, № 14. — P.1525—1531.

 

Monitoring the quality of life using a questionnaire SF-36 as a leading indicator prediction epidemiological situation tuberculosis 

Alexey N. Danilov, Candidate of Medical Science, associate professor of the Department of epidemiology of SBEI HPE «Saratov State Medical university of named after v.i. razumovsky» of Russian Ministry of Health, Russia, Saratov, tel. 8-845-2-26-16-90, e-mail: dispans@san.ru

Abstract. Aim. To analyze the possibility of using the index of quality of life as a leading indicator when assessing the epidemiological situation of tuberculosis in a particular area. Material and methods. With use the SF-36 were studied quality of life of 4861 residents of the Saratov region in period 2010—2013. Results. Found that reducing the quality of life increases the incidence of tuberculosis. It was found that, according to SF-36 of 2451 people living in the six districts of the Saratov region reduced quality of life to one conventional unit this year, predicts growth of tuberculosis on 0,53% thereafter. Discrepancies between predicted in the current year and the actual incidence of tuberculosis in the future in a particular area of the Saratov region by the developed technique is ranged 25,3—6,7% and averaged 15,8%. Revealed regularities allow us to recommend this method for use in medical practice. Conclusion. Monitoring the quality of life using the SF-36 may act as a leading indicator in predicting the epidemiological situation of tuberculosis in a particular area.

Key words: tuberculosis, epidemiology, prognosis, quality of life.

 

References

1. Barinboim, O.N. Mediko-ekonomicheskie vozmozhnosti optimizacii lecheniya tuberkuleza u bol'nyh s lekarstvennoi ustoichivost'yu: dis. … kand. med. nauk [Clinical and economic opportunities to optimize the treatment of tuberculosis in patients with drug-resistant] / Barinboim Ol'ga Nikolaevna. — M., 2009. — 143 s.
2. Belilovskii, E.M. Zabolevaemost' tuberkulezom v Rossiiskoi Federacii [The incidence of tuberculosis in the Russian Federation] / E.M. Belilovskii, S.E. Borisov, I.M. Son, O.B. Nechaeva // Tuberkulez v Rossiiskoi Federacii v 2011 g. Analiticheskii obzor statisticheskih pokazatelei, ispol'zuemyh v Rossiiskoi Federacii i v mire [Tuberculosis in the Russian Federation, 2011. Analytical review of the statistical indicators used in the Russian Federation for tuberculosis]. — M., 2013. — S.27—38.
3. Gnezdilova, E.V. Kachestvo zhizni u invalidov po tuberkulezu legkih [Quality of life of persons with disabilities to pulmonary tuberculosis] / E.V. Gnezdilova // Vos'moi Nacional'nyi kongress po boleznyam organov dyhaniya: sb. rezyume [8 National Congress on Respiratory Diseases: Proceedings resume]. — M., 1998. — S.481.
4. Guryleva, M.E. Kachestvo zhizni bol'nyh tuberkulezom na sanatornom etape lecheniya [Quality of life of patients with tuberculosis on sanatorium stage of treatment] / M.E. Guryleva, L.A. Gorbunova, O.V. Lovacheva, Z.H. Kornilova // Problemy tuberkuleza i boleznei legkih [Problems of Tuberculosis and Lung Disease]. — 2005. — № 7. — S.17—22.
5. Doktorova, N.P. Kliniko-ekonomicheskaya effektivnost' lecheniya molodyh bol'nyh infil'trativnym destruktivnym tuberkulezom legkih s raznoi stepen'yu social'noi adaptacii: dis. … kand. med. nauk [Clinical and economic effectiveness of treatment of young patients with infiltrative pulmonary tuberculosis with lung destruction and different level of their social adaptation] / Doktorova Natal'ya Petrovna. — M., 2007. — 152 s.
6. Kazimirova, N.E. Ekologo-epidemiologicheskaya harakteristika lekarstvenno-ustoichivyh form vozbuditelya tuberkuleza [Ecological and epidemiological characteristics Mycobacterium tuberculosis of drug-resistant] / N.E. Kazimirova, L.E. Parolina // Vestnik Rossiiskoi voenno-medicinskoi akademii [Bulletin of the Russian Academy of Military Medicine]. — 2008. — № 2(22), ch. 2. — S.408—409.
7. Morozova, T.I. Kriterii ocenki effektivnosti himioterapii v protivotuberkuleznom stacionare [Criteria for assessing the effectiveness of chemotherapy in a tuberculosis hospital] / T.I. Morozova, L.E. Parolina, N.P. Doktorova // Problemy tuberkuleza i boleznei legkih [Problems of Tuberculosis and Lung Disease]. — 2007. — № 6. — S.13—15.
8. Morozova, T.I. Tuberkulez legkih: social'nye problemy [Pulmonary tuberculosis: social problems] / T.I. Morozova, L.E. Parolina, V.I. Zavalev. — Saratov: SGMU, 2003. — 150 s.
9. P'yanzova, T.V. Kachestvo zhizni bol'nyh s vpervye vyyavlennym tuberkulezom legkih, poluchayuschih protivotuberkuleznuyu terapiyu na stacionarnom etape [Quality of life in patients newly diagnosed with pulmonary tuberculosis receiving TB treatment at a stationary stage] / T.V. P'yanzova, N.V. Luzina, O.A. Belikova [i dr.] // Tuberkulez i bolezni legkih [Tuberculosis and Lung Disease]. — 2011. — № 5. — S.130—131.
10. Suhovskaya, O.A. Ispol'zovanie obschih i special'nyh oprosnikov izucheniya kachestva zhizni v pul'monologii [The use of questionnaires of general and special study of quality of life in pulmonology] / O.A. Suhovskaya // Desyatyi Nacional'nyi kongress po boleznyam organov dyhaniya: sb. rezyume [10 National Congress on Respiratory Diseases: Proceedings resume]. — SPb., 2000. — S.187.

 

Result of total dissociation of gastroesophageal collector in patients with portal hypertension  

Feruz G. Nazyrov, Doctor of Medical Science, Professor, Director of Republican Specialized Center of Surgery of named after acad. V.Vahidov, Tashkent, Uzbekistan, tel. 8-371-233-49-09, e-mail: cs75@mail.ru

Andrey V. Devyatov, Doctor of Medical Science, Professor, chief researcher of the Department of surgery of portal hypertension and pancreatoduodenal zone of Republican Specialized Center of Surgery of named after acad. V.Vahidov, tashkent, uzbekistan, tel. 8-371-277-06-17, e-mail: avdevyatov1777@gmail.com

Azam Kh. Babadzhanov, Candidate of Medical Science, senior research fellow of the Department of surgery of portal hypertension and pancreatoduodenal zone of Republican Specialized Center of Surgery of named after acad. V.Vahidov, Tashkent, Uzbekistan, tel. 8-371-277-06-17, e-mail: azam747@mail.ru

Zhasur D. Zhamilov, surgeon of the Department of surgery of portal hypertension and pancreatoduodenal zone of Republican Specialized Center of Surgery of named after acad. V.Vahidov, Tashkent, Uzbekistan, tel. 8-371-277-06-17, e-mail: jasurdavronovich@gmail.com

Abstract. Aim. To study long-term results of the modified technique of total dissociation of gastroesophageal collec­tor (TDGEC) in patients with portal hypertension. Material and methods. A modified version of the operation carried out to 73 patients with the PH syndrome. In 36 patients the cause of PH was liver cirrhosis, 30 patients diagnosed with extrahepatic form of PH, 8 patients established a mixed form of PH. The age of patients ranged from 13 to 65 years, thus the mean was (31,6±1,7) years. Patients were distributed by gender as follows: men — 44, women — 29. 53 patients hospitalized in a planned order, and 20 patients delivered urgently with the clinic of gastroesophageal bleeding. Results and discussion. Remote period was followed up in 46 patients with primary procedure and 66 pa­tients with a modified technique of TDGEC. Rebleeding was observed in 15,2% of patients, and among them 6,5% were on anastomositis. Gastrostasis phenomenon was observed in 3 of 46 patients. The phenomenon of liver failure occurred in 23,9% of patients. On a background of these complications 15,2% patients died. In the group with a modified procedure bleeding observed in 6,0% of cases. Bleedings from erosion in the area of ligature transection were stopped conservatively. Mortality in long-term period of observation was 7,6% (5 patients). Overall mortality for the near and distant periods in the comparison groups was 22,2% and 16,4%, respectively. Conclusion. Interruption of gastroesophageal venous reservoir by ligature transection on synthetic prosthesis, unlike previously proposed methods of TDGEC not only alleviate technique of operation, but also provides prevention of early postoperative complications associated with traumatism of previous methods, as well as gross functional disorders of the stomach in the long term.

Key words: liver cirrhosis, portal hypertension, dissociative operations, technique of ligature transection, bleeding from esophageal varices.

 

References

1. Varianty tehnicheskogo sovershenstvovaniya razobschayuschih operacii u bol'nyh s portal'noi gipertenziei [Technical improvement of options of dissociative operations in patients with portal hypertension] / A.V. Devyatov, A.A. Mansurov, Sh.H. Hashimov [i dr.] // Hirurgiya Uzbekistana [Uzbekistan Surgery]. — 2002. — № 1. — C.19—22.
2. Taktika vedeniya bol'nyh s vnepechenochnoi portal'noi gipertenziei posle proshivaniya varikozno-rasshirennyh ven pischevoda i zheludka [Clinical management of patients with extrahepatic portal hypertension after suturing of esophageal varices and gastric] / A.K. Eramishancev, E.A. Kicenko, A.M. Nechaenko, R.S. Grigoryan // Annaly hirurgicheskoi gepatologii [Annals of Surgical Hepatology]. — 2002. — T. 10, № 1. — S.27—32.
3. Mansurov, A.A. Takticheskie aspekty i novye tehnologii razobschayuschih i rekonstruktivnyh shuntiruyuschih operacii u bol'nyh s portal'noi gipertenziei: avtoref. dis. … d-ra med. nauk [Tactical aspects and new technologies of dissociative and reconstructive bypass surgery in patients with portal hypertension] / A.A. Mansurov. — Tashkent, 2004. — 115 s.
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5. Endoscopic Hemostasis in Acute Esophageal Variceal Bleeding. / A. Cardenas, A. Baiges, V. Hernandez-Gea, J.C. Garcia-Pagan // Gastroenterol Clin. North Am. — 2014. — Vol. 43(4). — P.795—806.
6. Elkrief, L. Prospective Comparison of Spleen and Liver Stiffness by Using Shear-Wave and Transient Elastography for Detection of Portal Hypertension in Cirrhosis / L. Elkrief, P.E. Rautou, M. Ronot [et al.] // Radiology. — 2014. — Vol. 28. — P.141210—141214.
7. Fung, J.7. Management of chronic hepatitis B in severe liver disease / J. Fung, C.L. Lai, M.F. Yuen // World J. Gastroenterol. — 2014. — Vol. 20(43). — P.16053—16061.
8. Stefanescu, H8. Noninvasive assessment of portal hypertension in cirrhosis: Liver stiffness and beyond / H. Stefanescu, B. Procopet // World J. Gastroenterol. — 2014. — Vol. 20(45). — P.16811—16819.
9. Tandon, P9. Risk of Bacterial Infection in Patients with Cirrhosis and Acute Variceal Hemorrhage, Based on Child-Pugh Class, and Effects of Antibiotics / P. Tandon, J.G. Abraldes, A. Keough [et al.] // Clin. Gastroenterol. Hepatol. — 2014. — Vol. S1542. — P.3565—3569.

 

 

Practice orthopedic treatment of patients with maxillofacial pathology  

Alla I. Raff, Candidate of Medical Science, associate professor of the Department of prosthodontics and general dentistry of SBEI APE «Kazan State Medical Academy» of Russian Ministry of Health, Kazan, Russia, tel. 9-904-662-42-28, e-mail: ralla1@rambler.ru

Abstract. The purpose of the study was to conduct a clinical evaluation the effectiveness of treatment by functional devices with springy planes and its capability to move a deformed jaw fragments and teeth. As dysfunction of the temporomandibular joint in three mutually intersecting planes: vertical, sagittal and transversal. Material and methods. There was performed an analysis and treatment of 15 patients aged 16 to 30 years old with post-traumatic and postoperative maxillary deformities and diseases of the temporomandibular joint with fluoroscopic guidance, assessment of the state of the oral mucosa. Observed movements at 7th day with special meter scale: in vertical plane to 2 mm, in sagittal to 2 mm and from 1,5 to 2 mm in transversal plane. The decrease of pathological symptoms in temporomandibular joint dysfunction was demonstrated. Results and discussion. It was found that the application of functional equipment with springy planes can move deformed parts of the jaw and teeth in three mutually intersecting planes: vertical, sagittal, transversal which creates a significant therapeutic effect and rehabilitation of patients.

Key words: functional devices, springy planes.

 

References

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9. Patent 56170. Ros. Federaciya, MPK8 A61 K 31/21, A 61 P 23/02. Shina dlya lecheniya perelomov tela verhnei chelyusti [Splint for the treatment of fractures of the body of the maxilla] / I.Sh. Abdullin, M.M. Mironov, A.I. Raff, I.G. Yamashev; zayavitel' i patentoobladatel' GOU VPO «Kazanskii gosudarstvennyi tehnologicheskii universitet». — № 2005111500; zayavl. 18.04.2005; opubl. 10.09.2006, Byul. № 25. — 4 s.
10. Yаmashev, I.G. Nazubno-desnevye shiny dlya lecheniya perelomov chelyustei [Tooth-gingival splints for the treat­ment of fractures of the jaws] / I.G. Yаmashev, A.I. Raff // Aktual'nye voprosy chelyustno-licevoi hirurgii i stoma­tologii. — SPb., 1997. — C.66—67.

 

Nature association of polymorphism gene apolipoprotein B-100 with lipid metabolism in patients with cholelithiasis  

Aliya A. Sagdatova, graduate student of the Department of internal medicine propaedeutics of SBEI HPE «Bashkir State Medical university» of russian Ministry of Health, ufa, russia, tel. 8-917-772-59-60, e-mail: aliyasg@rambler.ru

Alfia Kh. Nurgalieva, Candidate of Medical Science, associate professor of the Department of genetics and fundamental medicine of FSBEI HPE «Bashkir State University», tel. (347) 2-299-671, e-mail: Alfiyakh83@gmail.com

Elsa K. Khusnutdinova, Doctor of Biological Science, Professor, Head of the Department of genetics and fundamental Medicine of FSBEI HPE «Bashkir State University», Head of the Department of genomics and human genetics laboratory of molecular of FSBDS «Institute of Biochemistry and Genetics, Ufa Scientific Center, Russian Academy of Sciences», Ufa, Russia, tel. (347) 2-299-671, e-mail: biodekanat@yandex.ru

Shamil Z. Zagidullin, Doctor of Medical Science, Professor, Head of the Department of internal medicine propaedeutics, of SBEI HPE «Bashkir State Medical University» of Russian Ministry of Health, Ufa, Russia, tel. (347) 246-53-97, e-mail: zshamil@inbox.ru

Abstract. Aim — analysis of the relationship of the polymorphic variant gene rs693 APOB-100 with lipid metabolism in patients with gallstone disease and healthy individuals residing in the Republic of Bashkortostan, Ufa. Material and methods. 54 patients with gallstone disease were divided into 2 groups: group 1 — patients with chronic calculous cholecystitis (21 patients), 2 group — patients with acute calculous cholecystitis (33 patients). Analysis of the lipid profile of blood serum of patients and typing of polymorphic gene locus rs693 APOB-100. Results. It was found that for gallstone disease marker of increased risk of disease is X+X-genotype of a polymorphic variant gene rs693 APOB-100. In the serum of patients with this pathology is set elevated levels of low density lipoprotein cholesterol and a high risk of atherosclerosis. It was established relationship between disorders of lipid metabolism and gallstone disease. Conclusion. The effect of the polymorphic variant gene rs693 APOB-100 on lipid metabolism and its disorders in patients with cholelithiasis.

Key words: cholelithiasis, gene polymorphism of apolipoprotein B-100, lipoproteins.

 

References

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14. Yoo, E.-H. The prevalence and risk factors for gallstone disease / E.-H. Yoo, S.-Y. Lee // Clin. Chem. Lab. Med. — 2009. — Vol. 47, № 7. — P.795—807.

 

Depression in neurological practice (in cases of pain syndromes and stroke)  

Dinara R.Teregulova, neurologist of City Clinical Hospital № 5, Ufa, Russia, tel. 8-987-249-15-35, e-mail: dinamail@mail.ru

Mansur A.Kutlubaev, Candidate of Medical Science, neurologist of Republican Clinical Hospital, assistant of professor of the Department of neurology, neurosurgery and medical genetics of SBEI HPE «Bashkir State Medical University» of Russian Ministry of Health, Ufa, Russia, tel. 8-347-228-75-00, e-mail: mansur.kutlubaev@yahoo.com

Leila R. Akhmadeeva, Doctor of Medical Science, Professor of the Department of neurology, neurosurgery and medical genetics of SBEI HPE «Bashkir State Medical University» of Russian Ministry of Health, Ufa, Russia, tel. 8-347-272-56-64, e-mail: la@ufaneuro.org

Abstract. Aim. To study the frequency and correlates of depression among inpatients with pain syndromes and after stroke. Material and methods. Two groups of patients were recruited: 125 patients with pain syndromes and 227 patients after stroke. Pain intensity was assessed by the questionnaire and Numerical Rating Scale (NRS), symptoms of depression were estimated using Hospital Anxiety and Depression Scale (HADS), Beck Depression Inventory and criteria of Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM–IV). Severity of neurological deficit and disability was assessed by National Institutes of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRs) respectively. Results and discussion. The results showed a high frequency of the symptoms of depression in both groups. In the group of patients with pain syndromes clinically significant depression according to HADS was observed in 34 (27,2%) cases, depression according to Beck Depression Inventory was diagnosed in 98 cases (78,4%). In the group of patients after stroke, depression according to DSM-IV criteria was detected in 49 (27,4%) patients. The severity of the symptoms of depression correlated with the intensity of pain and severity of neurological deficit after stroke. Conclusions. Depression often develops in patients with pain syndromes and after stroke. Its severity is associated with the severity of the main disorder. The development of depression in neurological disorders is likely to result in the formation of a vicious cycle: neurological symptoms lead to functional limitations and to the development of depression, whilst the latter in turn hampers the recovery process.

Key words: depression, pain syndrome, stroke.

 

 

References

1. Smulevich, A.B. Depressii v obschei medicine [Depression in general medicine] / A.B. Smulevich. — M.: Medicina, 2007. — S.100—107, 191—233.
2. Depressiya v nevrologicheskoi praktike [Depession in neurological practice] / A.M. Vein, T.G. Voznesenskaya, V.L. Golubev, G.M. Dyukova. — M.: Medicina, 2002. — S.20—30, 66-84.
3. Suslina, Z.A. Insul't: ocenka problemy (15 let problemy) [Stroke: assessment of the problem (15 years of challenges)] / Z.A. Suslina, M.A. Piradov, M.A. Domashenko // Zhurnal nevrologii i psihiatrii [Journal of Neurology and Psychiatry]. — 2014. — № 11. — S.5—13.
4. Kutlubaev, M. Part II: predictors of depression after stroke and impact of depression on stroke outcome: an updated systematic review of observational studies / M. Kutlubaev, M. Hackett // Int. J. Stroke. — 2014. — № 9. — P.1026—1036.
5. Vorob'eva, O.V. Klinicheskie osobennosti depressii v obschemedicinskoi praktike (po rezul'tatam program-my «Kompas») [Clinical features of depression in general practice (results of the program «Compass»)] / O.V. Vorob'eva // Consilium-Medicum [Consilium-medicum]. — 2004. — T. II, № 6. — S.9—56.
6. An inventory for measuring depression / A. Beck, C. Ward, M. Mendelson [et al.] // Arch. Gen. Psychiatry. — 1961. — № 4. — P.61—71.
7. D'yakonov, I.F. Psihologicheskaya diagnostika v praktike vracha [Psychological diagnosis in the practice] / I.F. D'yakonov, B.V. Ovchinnikov. — CPb.: SpecLit, 2008. — S.6—54.
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11. Orlov, A.I. Prikladnaya statistika: uchebnik [Applied Statistics. Tutorial] / A.I. Orlov. — M.: Ekzamen, 2006. — 671 s.
12. Validity of the Beck Depression Inventory, Hospital Anxiety and Depression Scale, SCL-90, and Hamilton Depression Rating Scale as Screening Instruments for Depression in Stroke Patients / I. Aben, F. Verhey, R. Lousberg [et al.] // Psychosomatics. — 2002. — Vol. 43. — P.386—393.
13. Furlanettoa, M. The Validity of the Beck Depression Inventory — Short form as a screening and diagnostic instrument for moderate and severe depression in medical inpatients / L. Furlanettoa, M. Mendlowiczbc, J. Buenob // J. of Affective Disorders. — 2005. — Vol. 86, № 1. — P.87—91.
14. Ahmadeeva, L.R. Trevozhnye i depressivnye sostoyaniya i ih svyaz' s bolevym sindromom u pacientov, nahodyaschihsya na stacionarnom lechenii [Anxiety and depressive states and their relation to the pain syndrome in hospitalized patients] / L.R. Ahmadeeva, D.R. Teregulova // Problemy zhenskogo zdorov'ya [Problems of women’s health]. — 2012. — T. 7, № 2. — S.23—28.
15. Kutlubaev, M.A. Neiroimmunnye mehanizmy v razvitii postinsul'tnoi depressii [Neuroimmune mechanisms in the development of poststroke depression] / M.A. Kutlubaev, L.R. Ahmadeeva // Zhurnal nevrologii i psihiatrii [Journal of Neurology and Psychiatry]. — 2013. — T. 113, № 2. — S.76—79.
16. Selective serotonin reuptake inhibitors for stroke recovery: a systematic review and meta-analysis / G. Mead, C. Hsieh, R. Lee [et al.] // Stroke. — 2013. — Vol. 44. — P.844—850.

 

Lipid metabolism in patients with coronary artery disease and comorbidities depending on stenosis of the left main coronary artery  

Gulnaz Z. Khalimova, candidate for a degree of the Department of faculty therapy and cardiology of SBEI HPE «Kazan State Medical university» of russian Ministry of Health, cardiologist of cardiology department № 1 of interregional clinical Diagnostic Center, Kazan, Russia, tel. 8-917-225-51-95, e-mail: gulnazm85@mail.ru

Albert S. Galyavich, Doctor of Medical Scienc, Professor, Head of the Department of faculty therapy and cardiology of SBEI HPe «Kazan State Medical university» of russian Ministry of Health, Kazan, russia, tel. 296-16-43, e-mail: agalyavich@mail.ru

Mikhail V. Panasyuk, Doctor of geographic Science, Professor, leading specialist of the Department of science and innovation of interregional clinical Diagnostic center, Kazan, russia, tel. 8-919-639-71-91, e-mail: mp3719@yandex.ru

Abstract. Aim. The study of lipid metabolism in patients with coronary heart disease (CHD) and comorbid disorders depending on stenosis of the left main coronary artery (LMCA). Material and methods. 138 people with CHD, defeat of the LMCA more than 50% and concomitant hypertension were included to the study. We separated groups with diabetes mellitus (DM) — 44 patients and without DM —94 patients. The comparative analysis between the groups and subgroups in order to planned coronary artery bypass surgery (CABG) and the degree of stenosis LMCA was held. Results. In the group without DM, subgroups awaiting CABG surgery (CABG +) and not awaiting CABG surgery (CABG–) differed significantly by sex and functional class of angina. In group with DM was found significant differences in levels of low density lipoprotein cholesterol (LDL). For patients without DM were determined subgroups with a relatively high (85,51%) and low stenosis (63,68%). The averages of total cholesterol (TC) and LDL differed slightly. In group with DM we had the subgroups with 78,9% and 60,6% stenosis respectively, where was showed significant differences. Comparing subgroups with relatively low stenosis of LMCA (63,7% in the group without DM and 60,6% in the group with DM) did not identified significant differences of LDL and TC. In subgroups with relatively high stenosis (85,5% and 78,9% respectively) there were found significant differences. Conclusion. DM, degree of stenosis LMCA significantly affects on lipid metabolism in patients with CHD and a significant stenosis of the LMCA.

Key words: the left main coronary artery, coronary heart disease, coronary artery bypass graft, diabetes mellitus.

 

References

1. Zhuk, M.Yu. Pokazateli aterotrombogennosti pri sochetanii arterial'noi gipertonii i dislipidemii u bol'nyh s raznoi vyrazhennost'yu koronarnogo ateroskleroza [Indicators of aterothrombogenicity in combination of hypertension and dyslipidemia in patients with varying severity of coronary atherosclerosis]: avtoref. dis. … kand. med. nauk / M.Yu. Zhuk. — M., 2004. — URL: http://www.dissercat.com/content/pokazateli-aterotrombogennosti-pri-sochetanii-arterialnoi-gipertonii-i-dislipidemii-u-bolny-0 (data obrascheniya: 18.04.2015).
2. Yarkov, V.I. Vliyanie narushenii lipidnogo obmena i trombocitarno-sosudistogo zvena gemostaza na disfunkciyu koronarnyh shuntov u bol'nyh IBS v sochetanii s essencial'noi arterial'noi gipertenziei [Influence of lipid metabolism and platelet-vascular hemostasis on coronary bypass grafts dysfunction in patients with coronary artery disease in combination with essential arterial hypertension]: avtoref. dis. … kand. med. nauk / V.I. Yarkov. — Novosibirsk, 2009. — URL: http://www.dissercat.com/content/vliyanie-narushenii-lipidnogo-obmena-i-trombotsitarno-sosudistogo-zvena-gemostaza-na-disfunk (data obrascheniya: 18.04.2015).
3. Gyenes, G.T. Should all patients with asymptomatic but significant (>50%) left main coronary artery stenosis undergo surgical revascularization / G.T. Gyenes, W.A. Ghali // Circulation. — 2008. — Vol. 118. — P.422—425.
4. Fajadet, J. Current management of left main coronary artery disease / J. Fajadet, A. Chieffo // Oxford Journals Medicine European Heart Journal. — 2011. — Vol. 33. — P.36—50.
5. Left main coronary angioplasty: early and late results of 127 acute and elective procedures / J.Jr. O'Keefe, G.O. Hartzler, B.D. Rutherford [et al.] // Am. J. Cardiol. — 1989. — Vol. 64. — P.144—147.
6. Left Main Coronary Artery Stenosis: factors predicting cardiac events in patients awaiting coronary surgery / S.S. Virani, C.E. Mendoza, A.C. Ferreira, E. de Marchena // Tex. Heart Inst. J. — 2006. — Vol. 33(1). — P.23—26.
7. Coronary Artery Bypass Graft Surgery vs Percutaneous Interventions in Coronary Revascularization: A Systematic Review / S. Deb, H.C. Wijeysundera, D.T. Ko [et al.] // JAMA. — 2013. — Vol. 310(19). — P.2086—2095.
8. Revascularisation for unprotected left main stem coronary artery stenosis: stenting or surgery / D. Taggart, S. Kaul, W.E. Boden [et al.] // J. Am. Coll. Cardiol. — 2008. — Vol. 51. — P.885—892.

 

Results of using magnetic-infrared-laser therapy in complex treatment of patients with new-onset destructive pulmonary tuberculosis  

Arkady L. Khanin, Doctor of Medical Science, Professor, Head of the Department of phthisiopulmonology of SEI APE «Novokuznetsk State Institute of Postgraduate Medical» of Russian Ministry of Health, honoured doctor of the Russian Federation, Novokuznetsk, Russia, tel. 384-345-48-73, 8-903-945-22-52, e-mail: prof.khanin@yandex.ru

Galina V. Pilnik, deputy chief physician of medical work of SAiH «Prokopevsky tB dispensaries», the highest category doctor, Prokopyevsk, Russia, tel. 384-662-62-94, 8-905-068-34-57, e-mail: galinapilnik@yandex.ru

Galina L. Nicotina, chief doctor of SAiH «Prokopevsky tB dispensaries», the highest category doctor, Prokopyevsk, russia, tel. 384-6-62-26-14, 8-960-907-67-69

Abstract. Aim. To compare the effectiveness of treatment of destructive, bacillary pulmonary tuberculosis in new-onset patients treated with standard chemotherapy and in patients who used complex magnetic-infrared-laser therapy (MIL-therapy) on the background of standard treatment of tuberculosis. Material and methods. The main group of 45 people received MIL-therapy on a background of standard chemotherapy, comparison group, 45 people received chemotherapy and vitamin therapy. Results and discussion. It was found that intoxication syndrome relief by the end of the first month was observed in 62,8% of patients of the main group, and in 40,6% of patients in the control group. Expressed or moderate resorption of infiltrative changes by the end of 2 months treatment was observed in 53,3% of patients in study group, and 24,4% in control group. Abacillation of mucus after three months of treatment was observed in 82,2% of patients of main group, and 51,1% of patients in control group. Cavities of decay were eliminated from 57,8% in study group and 8,8% of patients in control group after 6 months of treatment. Conclusion. Application of MIL-therapy on the affected lung’s projection enhances the effect of antibiotic treatment of destructive pulmonary tuberculosis due to the multi-faceted, complex effects on the main pathogenetic mechanisms of specific inflammation.

Key words: tuberculosis, bacterial excretion, the effectiveness of treatment, magnetic-laser therapy, abacillation, cavities of decay.

 

References

1. Vasil'ev, I.G. Rezul'taty kompleksnogo lecheniya hronicheskogo destruktivnogo tuberkuleza legkih s vklyucheniem v shemu MIL-terapii [Results of treatment of chronic destructive pulmonary tuberculosis with the inclusion in the scheme of MIL-therapy] / I.G. Vasil'ev // Aktual'nye voprosy tuberkuleza i drugih granulematoznyh zabolevanii: sb. materialov nauch.-prakt. konf. molodyh uchenyh [Actual problems of tuberculosis and other granulomatous diseases: collection of materials of scientific and practical conference of young scientists]. — M., 2001. — S.148—149.
2. Vasil'ev, A.P. Klinicheskii effekt nizkointensivnogo lazernogo izlucheniya kak rezul'tat formirovaniya adaptacii organizma [The clinical effect of low-intensity laser radiation as a result of the formation of the organism adaptation] / A.P. Vasil'ev, H.H. Strel'cova, M.A. Sekisova // Voprosy kurortnoi fizioterapii i lechebnoi fizkul'tury [Questions of resort physiotherapy and medical physical culture]. — 1999. — № 4. — S.49—51.
3. Gryaznova, D.A. Effektivnost' elektromagnitnogo izlucheniya kraine vysokoi chastoty v kompleksnoi terapii bol'nyh tuberkulezom legkih [The effectiveness of the electromagnetic radiation of extremely high frequency in the treatment of patients with pulmonary tuberculosis] / D.A. Gryaznova, A.A. Pozolotin, S.P. Hanina // Problemy tuberkuleza [Problems of tuberculosis]. — 1999. — № 4. — S.40—42.
4. Levchenko, G.I. Fizioterapiya v lechenii tuberkuleza legkih [Physiotherapy in the treatment of pulmonary tuberculosis] / G.I. Levchenko // Voenno-medicinskii zhurnal [Military Medical Journal]. — 2002. — № 5. — S.49—51.
5. Levashov, A.N. Vliyanie diodnogo izlucheniya s dlinoi volny 470 nm na effektivnost' lecheniya bol'nyh tuberkulezom legkih [Effect of diode radiation with a wavelength of 470 nm on the effectiveness of treatment of patients with pulmonary tuberculosis] / A.N. Levashov, V.V. Kir'yanova, T.I. Vinogradova // Fizioterapiya, bal'neologiya, reabilitaciya [Physiotherapy, balneology, rehabilitation]. — 2008. — № 4. — S.15—18.
6. Lomanchenkov, V.D. Fizioterapiya pri tuberkuleze legkih [Physiotherapy with pulmonary tuberculosis] / V.D. Lomanchenkov, A.K. Strelis. — M.: Medicina, 2000. — 136 s.
7. Lazeroterapiya v kompleksnom lechenii tuberkuleza legkih u podrostkov: posobie dlya vrachei [Laser therapy in the complex treatment of pulmonary tuberculosis in adolescents: A Manual for Physicians] / E.S. Ovsyankina, V.G. Dobkin, V.A. Firsova [i dr.] // Problemy tuberkuleza i boleznei legkih [Problems of tuberculosis and lung diseases]. — 2005. — № 1. — S.56—61.
8. Osnovnye pokazateli protivotuberkuleznoi deyatel'nosti v Sibirskom i Dal'nevostochnom federal'nyh okrugah [Key indicators of TB activities in the Siberian and Far Eastern Federal Districts] / O.V. Revyakina, T.V. Alekseeva, G.S. Murashkina [i dr.]. — Novosibirsk, 2012. — 87 s.
9. Parmon, E.M.9.Kombinirovannoe nizkointensivnoe lazernoe izluchenie pri tuberkuleze pochek [Combined low-intensity laser radiation when renal tuberculosis] / E.M. Parmon, V.S. Borschevskii, V.S. Kamyshnikov // Problemy tuberkuleza i boleznei legkih [Problems of tuberculosis and lung diseases]. — 2003. — № 6. — S.28—33.
10. Ftiziatriya: nacional'noe rukovodstvo [Physiotherapy: national leadership] / pod red. M.I. Perel'mana. — M.: GEOTAR-Media, 2007. — 512 s.
11. Fizioterapiya: nacional'noe rukovodstvo [Physiotherapy: national leadership] / pod red. G.N. Ponomarenko. — M.: GEOTAR-Media, 2009. — 864 s.
12. Hanin, A.L. Vliyanie mediko-social'nyh faktorov riska na effektivnost' lecheniya vpervye vyyavlennyh bol'nyh tuberkulezom [Effect of medical and social risk factors on the effectiveness of the treatment of newly diagnosed TB patients] / A.L. Hanin, S.A. Dolgih // Social'no znachimye bolezni: cb. materialov Mezhdunar. nauch.-prakt. konf. [Social significant diseases: Proc. International scientific-practical conference]. — Kemerovo, 2004. — S.55—57.
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14. Shilova, M.V. Tuberkulez v Rossii v 2012—2013 gg. [Tuberculosis in Russia in 2012—2013] / M.V. Shilova. — M., 2014. — 244 s.
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Healthcare organisation

State disability population city of Kazan in 1995—2011  

Nurikhan N. Shamsiyarov, Candidate of Medical Science, Honored doctor of the Republic of Tatarstan, deputy director of the organizational and methodical work of ICC, Kazan, Russia, tel. +7(927)-442-78-70, e-mail: kybm@mail.ru

Afgat N. Galiullin, Doctor of Medical Science, Professor of the Departmen of health management of SBEI HPE «Kazan State Medical University» of Russia Ministry of Health, Kazan, Russia, tel. +7(987)296-87-64, e-mail: kybm@mail.ru

Abstract. Aim. Provide data on disability population of the city of Kazan. Material and methods. It shows the extent and structure of primary disability of the adult population and persons of working age. Results and discussion. For the 1995—2011 biennium. are given information about the presence of growth primary disability in 2005 to 172,5±0,01 per 1,000 population due to the increase of diseases of the circulatory system and respiratory system, a significant reduction of disability in the population of the city of Kazan to 65,7±0,008 (1,000 of the population) occurred in 2011. The information about the reasons for the growth and reduce the levels of disability in the different periods of observation. The decrease in disability due to a decrease in the incidence of cases of diseases of the musculoskeletal system (90,6%), nervous system (60,7%), eyes (59,6%), circulatory system (38,4%), digestive (31,3%), malignant neoplasms (27,0%), a prognostic factor decrease of primary disability until 2016 will amount to 37,3%. Conclusion. The data obtained as a result of the study, it is recommended to use for predicting disability, planning treatment and prevention and rehabilitation measures.

Key words: primary exit to disability, disability, incidence, structure, dynamics.

 

References

1. Sistemnyi analiz razvitiya mediko-demograficheskih processov v megapolise v period social'no-ekonomicheskih reform: monografiya [System analysis of development of medico-demographic processes in the megalopolis during social and economic reforms: monograph] / A.N. Galiullin, N.N. Shamsiyarov, A.V. Glushakov [i dr]. — Kazan': Medicina, 2013. — 122 s.
2. Grishina, L.P. Osnovnye pokazateli pervichnoi invalidnosti v Rossiiskoi Federacii / L.P. Grishina // Statisticheskii sbornik. — M.: Federal'noe byuro mediko-social'noi ekspertizy, 2013. — 222 s.
3. Ihsanov, H.V. Mediko-social'nye aspekty invalidnosti trudosposobnogo naseleniya v Respublike Tatarstan [Medical and social aspects of disability of the working population in the Republic of Tatarstan] / H.V. Ihsanov // Mediko-social'naya ekspertiza i reabilitaciya. — 2007. — № 1. — S.5—8.
4. Kardakov, N.L. Zakonomernosti formirovaniya kontingenta invalidov molodogo vozrasta po obraschaemosti v byuro mediko-social'noi ekspertizy Rossiiskoi Federacii [Laws of formation of a contingent of young disabled uptake in the Bureau of Medical and Social Expertise of the Russian Federation] / N.L. Kardakov // Mediko-social'naya ekspertiza i reabilitaciya [Medical-social examination and rehabilitation]. — 2006. — № 3. — S.28—32.
5. Naumenko, L.L Analiz faktorov, vliyayuschih na pokazateli invalidnosti detskogo naseleniya [Analysis of factors affecting the performance of disability of the child population] / L.L. Naumenko. — 2012. — URL: http://iroddi28.ucoz.ru/publ/sotrudnikam/interesnye_stati/analiz_faktorov_vlijajushhikh_na_pokazateli_invalidnosti_detskogo_naselenija/10-1-0-12 (data obrascheniya: 15.12.2013).
6. P'yankova, I.V. Mediko-social'naya ekspertiza pri boleznyah organov dyhaniya [Medical and social expertise in diseases of the respiratory system] / I.V. P'yankova // Mediko-social'naya ekspertiza i reabilitaciya [Medical-social examination and rehabilitation]. — 2007. — № 3. — S.23—24.
7. Shlykova, M.V. Vozrastnye osobennosti pervichnoi invalidnosti vzroslogo naseleniya vsledstvie boleznei sistemy krovoobrascheniya v Rossiiskoi Federacii [Age characteristics of primary disability of the adult population as a consequence of diseases of the circulatory system in the Russian Federation] / M.V. Shlykova // Mediko-social'naya ekspertiza i reabilitaciya [Medical-social examination and rehabilitation]. — 2008. — № 8. — S.23—25.

 

Help for practitioner

New tool and method of tying surgical units in laparoscopic gynecological surgery  

Oleg V. Galimov, Doctor of Medical Science, Professor, Head of the Department of surgical diseases and new technologies of SBEI HPE «Bashkir State Medical University» of Russian Ministry of Health, Ufa, Russia, tel. +7 (347) 223-11-92, e-mail: kbgmu@rambler.ru

Elina Yu. Dmitrieva, obstetrician-gynecologist, a graduate student of the Department of surgical diseases and new technologies of SBEI HPE «Bashkir State Medical University» of Russian Ministry of Health, Ufa, Russia

Vladislav O. Khanov, Doctor of Medical Science, Professor of the Department of surgical diseases and new technologies of SBEI HPE «Bashkir State Medical University» of Russian Ministry of Health, Ufa, Russia, tel. +7-917-755-62-82, e-mail: khanovv@mail.ru

Oksana A. Filippova, obstetrician-gynecologist, a graduate student of the Department of surgical diseases and new technologies of SBEI HPE «Bashkir State Medical University» of Russian Ministry of Health, Ufa, Russia

Abstract. Aim. Implementation the devices for extracorporal knots setting in endoscopic operations in gynecologic practice. Material and methods. The Author's method was applied in clinic of BGMU in laparoscopic gynecologic interventions at 79 patients. Results and its discussion. During the observation of trial patients with applied technique of setting of extracorporal knots, we did not observe any complications bound to the offered way. Thus, we always observed adequate setting and a tightening of the ligature knots in hard-to-reach spots, and reached convenience in work when carrying out laparoscopic operations. Conclusion. We also noticed that use of the offered way allowed to increase convenience of formation of knots, to reduce time and injury of operation, to improve short-term results of treatment.

Key words: gynecology, laparoscopic surgery, the device for tying knots.

 

References

Fedorov, I.V. Oslozhneniya endoskopicheskoi hirurgii, ginekologii i urologii [Complications of Endoscopic Surgery, Gynecology and Urology] / I.V. Fedorov, E.I. Sigal, M.V. Burmistrov. — M.: Triada-H, 2012. — 283 s.

Panniculectomy and abdominoplasty in patients undergoing gynecologic surgery: a single center case series of 15 combined procedures / S.A. Wallace, A.F. Mericli, P.T. Taylor, D.B. Drake // Ann. Plast. Surg. — 2013. — № 71(1). — P.88—92.

 

The complex approach in treatment of children with congenital labium and palate clefts in Tatarstan Republic practice  

Pavel V. Tokarev, doctor fhighest category, maxillare facial surgeon, Head of the Department of maxillary facial surgery of SAIH «Children Republic Clinical Hospital», Kazan, Russia, e-mail: facesurg@yandex.ru

Alexey V. Shulaev, Doctor of Medical Science, Professor, Pro-rector of SBei HPe «Kazan State Medical university» of Russian Ministry of Health, Kazan, Russia

Ludmila V. Plaksina, Candidate of Medical Science, pediatrician, Head of the Department of SAIH «Children Republic Clinical Hospital», Kazan, Russia, e-mail: milaplax76@yandex.ru

Abstract. Introduction. The problem of treatment children with congenital maxillofacial region failure of development is actual nowadays, because of lack in complex specialized care system. Aim. To systemize the complex approach system in rehabilitation of children with this congenital defect, which was developed on previous rehabilitation scheme. Clinical-anatomical forms of clefts, patients somatic and neurological status, using own diagnostic and treatment methods were taken into account. This complex approach system in rehabilitation of children with congenital labium and palate clefts can allow to qualitatively prepare children to operative treatment in early period. It can reduce postoperative complications, improve function results. Conclusion. Full medical and social adaptation can be achieved only if the continuity and stages of treatment.

Key words: congenital maxillofacial region failure of development, congenital labium superior cleft, palate cleft, rehabilitation children with labium and palate cleft, psychological support to children with congenital maxillofacial region failure of development, congenital failures.

 

References

1. Blohina, S.I. Mediko-social'naya reabilitaciya bol'nyh s vrozhdennymi rasschelinami lica i nyoba v usloviyah specializirovannogo centra [Medical and social rehabilitation of patients with congenital facial cleft and palate in a specialized center]: avtoref. dis. … d-ra med. nauk / Blohina Svetlana Ivanovna. — M., 1992. — 49 s.
2. Gonchakov, G.V. Kompleksnaya reabilitaciya detei s vrozhdennymi rasschelinami verhnei guby i nyoba v NPC medicinskoi pomoschi detyam [Comprehensive rehabilitation of children with congenital cleft lip and palate in the NPC health care for children] / G.V. Gonchakov // Vrozhdennaya i nasledstvennaya patologiya golovy, lica i shei u detei: aktual'nye voprosy kompleksnogo lecheniya: materialy II Vseros. nauch.-prakt. konf. [Congenital and hereditary diseases of the head, face and neck in children: current issues of comprehensive treatment: Materials II All-Russia. scientific and practical. conf.]. — M., 2006. — S.48—49.
3. D'yakova, S.V. Sovremennyi podhod k dispanserizacii detei s vrozhdennoi patologiei chelyustno-licevoi oblasti [The modern approach to clinical examination of children with congenital pathology of maxillofacial area] / S.V. D'yakova, S.V. Yakovleva, M.A. Pershina // Vrozhdennaya i nasledstvennaya patologiya golovy, lica i shei u detei: aktual'nye voprosy kompleksnogo lecheniya: materialy II Vseros. nauch.-prakt. konf. [Congenital and hereditary diseases of the head, face and neck in children: current issues of comprehensive treatment: Materials II All-Russia. scientific and practical. conf.]. — M., 2006. — S.85—88.
4. Kobrynski, L.J. Velocardiofacial syndrome, DiGeorge syndrome: the chromosome 22q11.2 deletion syndromes / L.J. Kobrynski, K.E. Sullivan // Lancet. — 2007. — Vol. 370(9596). — P.1443—1452.
5. Stickler syndrome: clinical characteristics and diagnostic 5.           criteria / P.S. Rose, H.P. Levy, R.M. Liberfarb [et al.] // Am. J. Med. Genet. — 2005. — Vol. 138(3). — P.199—207.

 

Reviews

Closed heart injury on the prehospital

Alsu I. Abdrakhmanova, Candidate of Medical Science, associate professor of the Department of cardiology, roentgen-endovascular and cardiovascular surgery of SBEI APE «Kazan State Medical Academy» of Russian Ministry of Health, Kazan, Russia, tel. 8-917-922-66-29, e-mail: alsuchaa@mail.ru

Nail B. Amirov, Doctor of Medical Science, Professor of the Department of general medical practice of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, Kazan, Russia, e-mail: namirov@mail.ru

Nikolai A. Tsibulkin, Candidate of Medical Science, associate professor of the Department of functional diagnostics of SBEI APE «Kazan State Medical Academy» of Russian Ministry of Health, Kazan, Russia

Abstract. Aim. To analyze the last publications on the closed heart injury. Material and methods. To review the publications on etiology, pathogenesis, diagnostics, differential diagnostics and conservative treatment of closed heart injury. We analyzed the current state of this pathology: the leading mechanisms of signs and symptoms development. The most widespread clinical options of the closed heart injury were given: post-traumatic myocardial dystrophy, main vessels damage, sharp valve insufficiency, a myocardium rupture, a traumatic myocardial infarction, a heart bruise and heart concussion. Much attention was paid to classification by stages and clinical state, and by morphological disorders. We reviewed the state control measures and restoration of normal functioning of a cardiac muscle after the postponed trauma including rapid pain relief, arrhythmia attack and abnormal conductivity treatement, normalization of hemodynamic, restoration of contraction function of myocardium, myocardium metabolism improvement, and also prognosis for outcome. Conclusions. The closed heart injury often accompanies thorax injuries. Unconsciousness and traumatic shock complicate diagnosis. High frequency of late diagnostics delays the treatment and raise lethality. The closed heart injury has various clinical manifestations at different stages of the disease.

Key words: heart, closed trauma, diagnostics, treatment.

 

References

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10. Manykin, I.E. Ocenka funkcional'nogo sostoyaniya miokarda pri zakrytoi travme serdca [Assessment of a functional condition of a myocardium at the closed heart injury] / I.E. Manygin // Medicina kriticheskih sostoyanii [Medicine of critical conditions]. — 2005. — № 6. — S.16—20.
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18. Pimenov, L.T. Kliniko-funkcional'noe sostoyanie serdechno-sosudistoi sistemy pri zakrytoi travme grudnoi kletki [Clinical and functional condition of cardiovascular system at the closed thorax injury] / L.T. Pimenov, D.V. Korotaeva, N.N. Solov'eva [i dr.]// Prakticheskaya medicina [Practical medicine]. — 2011. — № 4. — S.90—92.
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24. Tumanov, E.V. Teorii povrezhdeniya serdca pri tupoi travme grudnoi kletki [Theories of injury of heart at blunt injury of a thorax] / E.V. Tumanov, Z.Yu. Sokolova // Cudebnaya medicinskaya ekspertiza [Judicial medical examination]. — 2010. — № 6. — S.44—48.
25. Federal'nye klinicheskie rekomendacii po diagnostike i lecheniyu narushenii ritma i provodimosti serdca [Federal clinical recommendations on diagnostics and treatment of disorders of rhythm and conductivity of heart]. — M., 2013. — URL: http://www.acutecardio.ru/article/21/federalnyie-klinicheskie-rekomendatsii-po-diagnost (data obrascheniya: 13.05.2015).
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27. Chepen', A.I. Kliniko-elektrokardiograficheskaya harakteristika sotryasenii serdca [Clinical and electrocardiographic characteristic of concussions of heart] / A.I. Chepen', V.G. Marchuk, V.V. Chizh // Zdorov'e. Medicinskaya ekologiya. Nauka [Health. Medical ecology. Science]. — 2012. — № 1/2 — S.54.
28. Shepelenko, A.F. Diagnostika i lechenie sochetannoi patologii legkih i serdca pri travme v usloviyah terapevticheskogo stacionara [Diagnostics and treatment of the combined pathology of lungs and heart at a trauma in the conditions of a therapeutic hospital] / A.F. Shepelenko, N.D. Shepelenko, M.M. Kirillov // Pul'monologiya [Pulmonology]. — 2004. — № 4. — S.81—86.
29. Shepelenko, A.F. Patologiya vnutrennih organov pri travme v terapevticheskoi klinike [Pathology of internal organs at a trauma in therapeutic clinic] / A.F. Shepelenko, M.M. Kirillov, N.D. Shepelenko. — M.: MIA, 2007. — 333 s.

 

Cardioprotective effect of ischemic conditioning  

Aydar Z. Sharafeev, Doctor of Medical Science, Head of the Department of cardiology, endovascular
and cardiovascular surgery of SBEI APE «Kazan State Medical Academy» of Russian Ministry of Health, Head of cath-lab of SAIH RCH № 2, Kazan, Russia, e-mail: aidarch@mail.ru

Vilay A. Bayazitova, graduate student of the Department of cardiology, endovascular and cardiovascular surgery of SBEI APE «Kazan State Medical Academy» of Russian Ministry of Health, Kazan, Russia, tel. 8-905-349-15-03, e-mail: vilionora@yandex.ru

Aliya R. Iskhakova, functional diagnostic’s doctor of diagnostic department of SAIH RCPH
of name after acad. V.M. Bekhterev, Kazan, Russia, e-mail: al-rust@mail.ru

Abstract. Aim. To analyze the recent publications on the problem of cardioprotection in acute myocardial infarction (AMI). Material and methods. A review the recent publications on the various methods of cardioprotection which reduce the infarct size compared to placebo. Results and discussion. Despite the progress in the treatment of acute myocardial infarction, mortality from this disease persists the leading place. The current standard therapy does not reduce the size of myocardial necrosis. In this article we review current issues of cardioprotection: mechanical and physical methods based on the recent clinical trials. Throw light upon main aspects of ischemic conditioning, mild hypothermia and supersaturated oxygen therapy. Analyzed last two recent large randomized trials RAPID-MI-ICE and AMIHOT II published in 2010 and 2009, respectively. Conclusions. Ischemic conditioning proved its cardioprotective properties in several clinical trials.

Key words: acute myocardial infarction, cardioprotection, ischemic conditioning.

 

References

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Correspondence

Electronic cigarettes — «way of smoking» or quit smoking devices? Commentary article on V.D. Mendelevich  

Peter K. Yablonsky, Doctor of Medical Science, Professor, Director of FSBI «Saint Petersburg Research Institute for Phthisiopulmonology» of Russian Ministry of Health, Saint Petersburg, Russia, tel. 8-812-579-25-54, e-mail: spbniif_all@mail.ru

Olga A. Sukhovskaya, Doctor of Medical Science, Head of the advisory call center for tobacco consumption quitting of FSBI «Saint Petersburg Research Institute for Phthisiopulmonology» of Russian Ministry of Health, Saint Petersburg, Russia, tel. 8-800-200-02-00, e-mail: ktc01@mail.ru

Abstract. The article is a comment on V.D. Mendelevich’s article published in Bulletin of modern clinical medicine Vol. 8 Issue 2 [7]. International statements, as the basis of the fight against tobacco smoking in the world are presented. The authors believe that electronic cigarettes (ES) and electronic nicotine delivery systems (ENDS) can not be recommended for tobacco addiction treatment. Also noted, that our country has registered medications for tobacco addiction treatment with higher efficiency. Doctor or health care worker trained in carrying out cognitive behavioral therapy and assistance in quitting smoking, is capable to increase the chances of long-term smoking cessation in 1,84 times at individual counseling for smoking cessation. We disputed the conception ES as a therapeutic agent, and that’s why they can not be recommended by physicians.

Key words: electronic cigarettes, smoking cessation, tobacco addiction.

 

References

1. Zhu, S.-H. Four hundred and sixty brands of e-cigarettes and counting: implications for product regulation / S.-H. Zhu, J.Y. Sun, E. Bonnevie [et al.] // Tobacco Control. — 2014. — Vol. 23. — P.iii3—iii9. — doi:10.1136/tobaccocontrol-2014-051670
2. Grana, R. E-cigarettes: a scientific review / R. Grana, N. Benowitz, S.A. Glantz // Circulation. — 2014. — Vol. 129. — P.e490–e492. — doi:10.1161/ CIRCULATIONAHA. 114.008545
3. Doklad VOZ «Electronic nicotine delivery systems». — URL: http://apps. who.int/gb/fctc/PDF/cop6/FCTC_COP6_10-en.pdf?ua=1
4. Global'nyi opros vzroslogo naseleniya o potreblenii tabaka (GATS) [A global survey of the adult tobacco consumption (GATS)]; Rossiiskaya Federaciyay. — M., 2009. — 171 s.
5. Suhovskaya, O.A. Social'nye aspekty tabakokureniya zhenschin [Social aspects of female tobacco consumption] / O.A. Suhovskaya, O.V. Lavrova, E.A. Shapovalova // Zhurnal akusherstva i zhenskih boleznei. — 2011. — № 2. — C.115—119.
6. Amirov, N.B. Tabachnaya epidemiya: farmakologicheskie vozmozhnosti bor'by [Tobacco epidemic: pharmacological possibilities of struggle] / N.B. Amirov, T.I. Andreeva // Vestnik sovremennoi klinicheskoi mediciny [Bulletin of Contemporary Clinical Medicine]. — 2011. — T. 4, vyp. 3. — S.28—33.
7. Mendelevich, V.D. Pol'za i vred elektronnyh sigaret skvoz' prizmu raznyh terapevticheskih metodologii [Benefits and harm of electronic cigarettes through the prism of different therapeutic methodologies] / V.D. Mendelevich // Vestnik sovremennoi klinicheskoi mediciny [Bulletin of Contemporary Clinical Medicine]. — 2015. — T. 8, № 2. — C.61—73.
8. Suhovskaya, O.A. Pomosch' pri otkaze ot kureniya [Help with smoke quitting] / O.A. Suhovskaya // Doktor.ru. — 2010. — T. 6, № 57. — S.41—44.
9. Stead, L.F. Physician advice for smoking cessation / L.F. Stead, G. Bergson, T. Lancaster // The Cochrane Library. — 2008. — Issue 4.
10. Yablonskii, P.K. Organizaciya konsul'tativnoi telefonnoi pomoschi pri otkaze ot tabakokureniya v Rossiiskoi Federacii [Organization of telephone advisory help in smoking cessation in the Russian Federation] / P.K. Yablonskii, O.A. Suhovskaya // Zdravoohranenie Rossiiskoi Federacii. — 2014. — № 1. — C.30—33.

 

When the issue was in press

Publication ethics and editorial policy of journal «The bulletin of contemporary clinical medicine»  

Nail B. Amirov, D.Med.Sci., Prof. of the Department of general medicine practice of SBEI HPE «Kazan State Medical university» of russian Ministry of Health, Honored Science and education Worker, Acad. of rAnH, tr Honored Doctor, State Honoree of TR in Science and Technics, Editorial Board of journal «The bulletin of contemporary clinical medicine», Kazan, Russia, e-mail: namirov@mail.ru

Alexander A.Vizel, D.Med.Sci., Prof., Head of the Department of phthisiopulmonology of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, Honored Doctor of TR, State Honoree of TR in Science and Technics, Deputy Editor in chief of journal «The bulletin of contemporary clinical medicine», Kazan, Russia, e-mail: lordara@inbox.ru

Maria A. Daminova, C.Med.Sci., assistant of professor of Department of pediatrics and neonatology of SBEI APE «Kazan State Medical Academy» of Russian Ministry of Health, Responsible Secretary of journal «The bulletin of contemporary clinical medicine», Kazan, Russia, tel. +7-917-262-47-79, e-mail: daminova-maria@yandex.ru

Renata N. Amirova, doctor-expert of Open joint-stock company ICGI, Chief of Marketing department of journal «The bulletin of contemporary clinical medicine», Kazan, Russia, tel. +7-903-307-99-47, e-mail: renata1980@mail.ru

Rustem I. Shaymuratov, graduate student of the Department of phthisiopulmonology of SBEI HPE «Kazan State Medical university» of russian Ministry of Health, computer support and web version of journal «the bulletin of contemporary clinical medicine», Kazan, Russia, tel. +7-917-900-55-10, e-mail: russtem@gmail.com

Abstract. In the modern era of scientific communication journals must declare publication ethics and editorial policy to be included in international databases. To develop specified up-to-date recommendations we studied the latest publications and international statements. In current article we discussed ethical aspects of biomedical research, publications transparency. Autorship criteria, conflict of interest and editorial board conflict of interest (when members of the editorial board publish in own journal) were described. Reviewer’s ethics was also declared. We gave the definition of autoplagiarizm and provided instructions to avoid it. Retraction guidelines were also showed and information about how we treat articles that are ready to be retracted.

Key words: publication ethics, editorial policy, peer-review, transparency.

 

References

1. Guidance for Editors: Research, Audit and Service Evaluations.— URL: http://publicationethics.org/resources/guidelines URL: www.singaporestatement.org
2. A short guide to ethical editing for new editors.— URL: http://publicationethics.org/resources/guidelines
3. Retraction guidelines.— URL: http://publicationethics.org/ resources/guidelines
4. Croat Med. J. 2013;54:600-8; doi: 10.3325/cmj.2013.54.600 Armen Yuri Gasparyan, Lilit Ayvazyan, Nurbek A. Akazhanov, George D. Kitas a.gasparyan@gmail.com Conflicts of interest in biomedical publications: considerations for Authors, peer reviewers and editors.