Vol. 8 Issue 4 (2015)

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Original Articles

Changes in cardiac hemodynamics depending on method of surgical myocardial revascularization. Abzalov G.F., Mayanskaya S.D.,Teregulov Yu.E., Abashin I.O., Khayrullin R.N.

Comparative effect of metabolic therapy in different forms of chronic ischemic heart disease. Amirov N.B., Tsibulkin N.A., Morozova A.A., Mikhoparova O.Ju., Oschepkova O.B.

Predictors of mortality from community-acquired pneumonia in the modern conditions of pulmonology center. Borodulina E.A., Borodulin B.E., Povaljaeva L.V., Chernogaeva G.Yu., Vdoushkina E.S.

Modern nutrition in patients with late onset asthma. Goremykina M.S., Kupaev V.I., Sazonova O.V., Gorbachev D.O., Yakunova E.M., Galitskaya A.V.

Development of organizational and economic approaches for pharmacy manufacture of medicines (pharmacy № 361 of state enterprise «Tattechmedpharm» as the example). Tukhbatullina R.G., Davletova G.R., Galeeva Z.M.

Influence of radio frequency electromagnetic radiation on the tissues of heart and vessels in the experiment. Khamidova G.M.

Application of complex influence of several physiotherapy methods for increase of treatment efficacy in newly diagnosed destructive forms of pulmonary tuberculosis. Khanin A.L., Pilnik G.V., Nicotina G.L.

Clinical-pathogenetic reasoning of multimodal analgesia adequacy in peryoperative period in long-termed traumatic abdominal operative interventions. Sharipova V.Kh.

Experience Exchange

Experience of treatment maxilla fractures and deformations by laboratory manufactured splints. Raff A.I.

Help For Practitioner

Functional method of temporomandibular joint dysfunction treatment. Raff A.I.

Reviews

Immune disorders in children with atopic dermatitis combinated with chronic diseases. Davletbaeva G.R.

Diagnosis and treatment the diabetic comas according to recent recommendations of the management of patients with diabetes mellitus. Maiorova E.M., Garipova A.F.

Respiratory support of patients in acute period of subarachnoid hemorrhage. Shpaner R.Ya.

 

Original Articles

PDF downloadChanges in cardiac hemodynamics depending on method of surgical myocardial revascularization 

Abzalova Guzel F., graduate student of the Department of hospital therapy of Kazan State Medical University, Kazan, Russia, tel. 7 (906)-320-70-79, e-mail: guzelka88@bk.ru

Mayanskaya Svetlana D., D.Med.Sci., Professor of the Department of hospital therapy of Kazan State Medical university, Kazan, Russia, tel. +7(905)-316-99-66, e-mail: Smayanskaya@mail.ru

Teregulov Yuriy E., C.Med.Sci., Head of the Department of functional diagnostic of Republican Clinical Hospital, Kazan, Russia, tel. 8(917)-264-70-04, e-mail: tereg2@mail.ru

Abashin Igor O., cardiologist, Head of the Department of cardiology of Republican Clinical Hospital № 2, Kazan, Russia, tel. 8(937)-299-39-36, e-mail: guzelka88@bk.ru

Khayrullin Rustem N., D.Med.Sci., Director of Interregional Clinical and Diagnostic Center, Kazan, Russia, tel. +7(843)-291-11-04, e-mail: icdc.science@gmail.com

  1. Aim. To compare the changes of cardiac hemodynamics during recovery period in patients undergone coronary artery bypass surgery depending on methods of surgical treatment and in the existence of postinfarction cardiosclerosis. Material and methods. 104 people suffering from IHD were examined (25 women and 79 men), aged from 39 to 85 years. All patients had coronary artery bypass surgery (CABG) or mammo-coronary bypass surgery (MCBS) with the imposition of 1—2 or more than 3 shunts. All patients were divided into 4 groups: the first group consisted of patients with postinfarction cardiosclerosis (PIC), which CABG was performed with extracorporeal circulation and pharmaco-cold cardioplegia (PCC) (47 patients); the second group consisted of 27 patients without PIC, which CABG was performed with extracorporeal circulation and PCC too; the third group consisted of 14 patients with PIC, who had CABG with off-pump coronary artery bypass (OPCAB) using; the fourth group consisted of 16 patients without PIC, with OPCAB using too. All patients before, 7 days and 4 months after CABG had studied cardiac hemodynamic parameters by volume compression oscillometry, analyzers of blood circulation APCO-8-RIP (the company «Seth», Kazan). Results and discussion. The method of surgical revascularization significantly affect the stabilization of cardiac hemodynamics in the postoperative period. Myocardial infarction significantly slowed heart inotropic function recovery in both methods CABG. By the 4th month after CABG was observed positive dynamics in both groups of patients. However, in patients after CABG under OPCAB these changes are more pronounced than in the comparison group. Conclusion. The results will optimize rehabilitation activities in the postoperative period, depending on the method of surgical treatment, and these indicators will serve as a cardiac hemodynamic indicators of the effectiveness of these measures.

Key words: coronary artery bypass grafting (CABG) with extracorporeal circulation and pharmaco-cold cardioplegia, off pump coronary artery bypass (OPCAB), postinfarction cardiosclerosis infarction; cardiac hemodynamics, the volume compression oscillometry.

 

For reference: Abzalova GF, Mayanskaya SD, Teregulov UE, Abashin IO, Khayrullin RN. Changes in cardiac hemodynamics depending on method of surgical myocardial revascularization. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 7—12.

 

References

  1. Bokerija LA, Gordeev ML, Avaliani VM. Aortokoronarnoe shuntirovanie na rabotajushhem serdce: sovremennyj vzgljad na problem [Off Pump Coronary Artery Bypass: a modern view on the problem]. Grudnaja i serdechno-sosudistaja hirurgija [Thoracic and Cardiovascular Surgery]. 2013; 4: 4-15.
  2. Emmert MY, Salzberg SP, Seifert B, Rodriguez H, Plass A, Hoerstrup SP et al. Is off-pump superior to conventional coronary artery bypass grafting in diabetic patients with multivessel disease? Eur J Cardiothorac Surg. 2011; 40: 233–239.
  3. Bokerija LA, Merzljakov VJu, Kljuchnikov IV. Otdalennye rezul'taty i kachestvo zhizni pacientov posle operacii revaskuljarizacii miokarda na rabotajushhem serdce [Long-term results and the quality of life of patients after Off Pump Coronary Artery Bypass]. Serdechno-sosudistaja hirurgija [Cardiovascular Surgery]. 2007; 4: 3-11.
  4. Bokerija LA, Avaliani VM, Merzljakov VJu. Aortokoronarnoe shuntirovanie na rabotajushhem serdce [Off Pump Coronary Artery Bypass]. M:NCSSH im. A.N. Bakuleva RAMN; 2008.
  5. Akchurin RS, Shirjaev AA. Aktual'nye problemy koronarnoj hirurgii [Actual problems of coronary surgery]. M: GEOTAR-MED. 2004; 86 р.
  6. Akchurin RS, Shirjaev AA, Brand JaB, Korolev SV, Galjautdinov DM, Vasil'ev VP. Rekonstruktivnaja mikrohirurgija koronarnyh arterij: opyt pervyh 2000 operacij [Reconstructive microsurgery of the coronary arteries: the experience of the first 2,000 transactions]. Sbornik statej po Materialam Vserossijskoj nauchnoprakticheskoj konferencii «Sovremennye tehnologii hirurgii ishemicheskoj bolezni serdca» [Collection of articles on scientific and practical Proceedings of the conference «Modern technologies of surgery for coronary heart disease»]. M, 2001; 1315.
  7. Lynn GM, Stefanko K, Reed JF, Gee W, Nicholas G. Risk factors for stroke after coronary artery bypass. Journal of Thoracic and Cardiovascular Surgery. 2000; 104 (6): 1518-1523.
  8. Halkos ME, Vassiliades TA, Douglas JS, Morris DC, Rab ST, Liberman HA et al. Hybrid coronary revascularization versus off-pump coronary artery bypass grafting for the treatment of multivessel coronary artery disease. Ann Thorac Surg. 2011; 92: 1695–1701; discussion 1701–1702; 2155–2160.
  9. John R, Choudhri AF, Weinberg AD, Ting W, Rose EA, Smith CR. Multicenter review of preoperative risk factors for stroke after coronary artery bypass grafting. Annals of Thoracic Surgery. 2000; 69: 30-35.

 

PDF downloadComparative effect of metabolic therapy in different forms of chronic ischemic heart disease 

Amirov Nail B., D.Med.Sci., Professor of the Department of general medical practice of Kazan State Medical University, Kazan, Russia, e-mail: namirov@mail.ru

Tsibulkin Nikolay A., C.Med.Sci., associate professor of the Department of functional diagnostics of Kazan State Medical Academy, Kazan, Russia

Morozova Anastasia A., therapist of the Department of therapy of Bugulma Central Regional Hospital, Bugulma, Russia

Mikhoparova Olga J., Head of the Department of functional diagnostics of Hospital MVD, Kazan, Russia

Oschepkova Olga B., Head of the Department of cardiology of Hospital MVD, Kazan, Russia

  1. Aim. Assessment of metabolic therapy effect in patients with various forms of chronic ischemic heart disease based on trimetazidin study. The assessment of clinical effect of treatment, influence of treatment on condition of myocardium and its function, structural parameters of heart, and on dosed physical activity. Material and methods. Patients took part in research with the diagnosis confirmed according to clinical, technical and laboratory data. Patient’s characteristics varied from stable angina as isolated form to its combination with other forms of chronic heart diseases. Research was conducted according to the following protocol. The first inspection included an assessment of clinical symptoms, a standard electrocardiography, Holter monitoring, an echocardiography under the standard protocol with left ventricle function assessment, the 6-minute walking test. Frequency of angina attacks, breathlessness, and heart intermittence were assessed. The sizes of heart cameras, thickness of walls and integral function of left ventricle were defined. Also arrhythmia, conductivity disorders, symptoms of myocardium ischemia were checked. During treatment control examinations were conducted. Results and discussion. Application of metabolic therapy in complex with standard drug treatment at patients with various forms of chronic ischemic heart disease leads to improvement various functional indicators. Trimetazidin introduction decreased angina attacks and physical activity breathlessness episodes. The received results confirm validity of inclusion this treatment in complex therapy of patients with chronic ischemic heart disease. Conclusion. Demonstrated, that even medium-term metabolic therapy in patients with various forms of chronic ischemic heart disease reduces symptoms of a disease, improves a functional condition of a myocardium and increases exercise tolerance.

Key words: metabolic therapy, chronic ischemic heart disease, echocardiography, 6 minute walk test.

 

For reference: Amirov NB, Tsibulkin NA, Morozova AA Mihoparova OJ, Oschepkova OB. Comparative effect of metabolic therapy in different forms of chronic ischemic heart disease. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 12—19.

 

References

  1. Oganov RG, Maslennikova GJa. Profilaktika serdechnososudistyh i drugih neinfekcionnyh zabolevanij — osnova uluchshenija demograficheskoj situacii v Rossii [Prevention of cardiovascular and other noninfectious diseases — a basis of improvement of a demographic situation in Russia]. Kardiovaskuljarnaja terapija i profilaktika [Cardiovascular therapy and prevention]. 2005; 3: 4-9.
  2. Nacional'nye rekomendacii po diagnostike i lecheniju stabil'noj stenokardii [National recommendations about diagnostics and treatment of stable angina]. Kardiovaskuljarnaja terapija i profilaktika [Cardiovascular therapy and prevention]. 2008; 7(6); 4.
  3. Metelica VI. Spravochnik po klinicheskoj farmakologii serdechno-sosudistyh sredstv [Reference book on clinical pharmacology of cardiovascular medicines]. M : Medpraktika. 1996: 784 р.
  4. Okorokov AN. Lechenie boleznej vnutrennih organov [Treatment of diseases of internals]. Lechenie zabolevanij serdechno-sosudistoj sistemy [Treatment of diseases of cardiovascular system]. Mn: Vysh shk. 1997; 3 (1): 464 р.
  5. Chuchalina AG, Belousova JuB, Jasnecova VV editors. Federal'noe rukovodstvo po ispol'zovaniju lekarstvennyh sredstv (formuljarnaja sistema) [Federal operating instructions of medicines (official system)]. 2nd ed. M.: OOF «Zdorov'e cheloveka». 2008; 9: 998 р.
  6. Denisova IA, Shevchenko JuL editors. Klinicheskie rekomendacii — Farmakologicheskij Spravochnik [Clinical recommendations — Pharmacological Reference book]. M : GJeOTAR-MED. 2004:1184 р.
  7. Chоukhnin EV, Amirov NB. The heart rate variability: method and clinical application/ The Bulletin of Contemporary Clinical Medicine. 2008; 1: 72-78.

 

PDF downloadPredictors of mortality from community-acquired pneumonia in the modern conditions of pulmonology center 

Borodulina Elena A., D.Med.Sci., Professor, Head of the Department of tuberculosis and pulmonology of Samara State Medical University, tel. +7(846)-332-57-35, e-mail: borodulinbe@yandex.ru

Borodulin Boris E., D.Med.Sci., Professor the Department of tuberculosis and pulmonology of Samara State Medical University, tel. +7(846)-332-57-35, e-mail: borodulinbe@yandex.ru

Povaljaeva Ljudmila V., associate professor of the Department of tuberculosis and pulmonology of Samara State Medical University, tel. +7(846)312-55-18, e-mail: povalyaevalv8@rambler.ru

Chernogaeva Galina Yu., assistant of professor of the Department of tuberculosis and pulmonology of Samara State Medical University, e-mail: gali-c@yandex.ru

Vdoushkina Elizaveta S., clinical resident of the Department of tuberculosis and pulmonology of Samara State Medical University, tel. +7(987)-945-18-22, e-mail: vdoushkina@rambler.ru

  1. Aim — to study the predictors of mortality from community-acquired pneumonia in Samara pulmonology center from 2004 to 2014. Material and methods. The study included 879 patient records over the study period, hospitalized through the emergency department and intensive care units. Study group made up the patients who died, the control group were recovering patients transferred to the general ward and transferred to outpatients. Results and discussion. The analysis showed that there were significant changes: the deaths of community-acquired pneumonia in HIV patients was 36% of all deaths (2004 — 0%), pneumonias occurred as a complication of the pathogenic H1N1 influenza appeare, which led to death in 21,3% of cases; the mortality from tuberculosis was 10?7% (2004 — 0%). Conclusion. The number of late admissions, emergency care admissions increases, man death increased, age of dead patients decreased almost by 8 years.

Key words: community-acquired pneumonia, mortality, hospital, intensive care, HIV-infection/

 

For reference: Borodulina EA, Borodulin BE, Povaljaeva LV, Chernogaeva GJu ,Vdoushkina ES. Predictors of mortality from community-acquired pneumonia in the modern conditions of pulmonology center. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 19—22.

 

References

  1. Bilichenko TN, Chuchalin AG, Son IM. Osnovnye itogi razvitija specializirovannoj medicinskoj pomoshhi bol'nym pul'monologicheskogo profilja na territorii Rossijskoj Federacii za period 2004–2010 gg. [Main results of specialized medical care to patients with pulmonary profile of the Russian Federation for the period of 2004-2010]. Pul'monologija [Pulmonology] 2012; 3: 5-16.
  2. Vizel' AA, Vizel' IJu, Lysenko GV. Vnebol'nichnaja pnevmonija kak rasprostranennoe ostroe infekcionnoe zabolevanie organov dyhanija [Community-acquired pneumonia as a common acute infectious disease of the respiratory system]. Medicinskij sovet [Medical Council] 2014; 16: 44-47.
  3. Chuchalin AG. Klinicheskie rekomendaciii. Pul'monologija [Clinical guidelines. Pulmonology], red. A.G. Chuchalina. M.:GJeOTAR-Media, 2005; 240.
  4. Povaljaeva LV, Borodulin BE, Borodulina EA, Chernogaeva GJu, Chumanova ES. Faktory riska smerti pacientov s vnebol'nichnoj pnevmoniej v sovremennyh uslovijah [Modern death risk factors in patients with community-acquired pneumonia]. Kazanskij medicinskij zhurnal [Kazan Medical Journal] 2012; 93 (5): 816-820.
  5. Povaljaeva LV, Borodulina EA, Borodulin BE, Eremeev AE. Vpervye vyjavlennyj tuberkulez legkih i sposob ego vyjavlenija [Newly diagnosed pulmonary tuberculosis and the method of detection]. Tuberkulez i bolezni legkih [Tuberculosis and Lung Disease] 2011; 88 (5): 113-114.
  6. Sinopal'nikov AI, Fesenko OV, Tihonov JuG, Duganov VK. Tjazhelaja vnebol'nichnaja pnevmonija: jetiologicheskaja struktura [Severe community-acquired pneumonia: etiological structure]. Antibiotiki i himioterapija [Antibiotics and Chemotherapy] 2001; 46 (6): 6–11.
  7. Sinopal'nikov AI, Kozlov RS, Rachina SA, Dehnich NN. Sovremennye rekomendacii po vedeniju bol'nyh vnebol'nichnoj pnevmoniej [Current recommendations for management of patients community-acquired pneumonia]. Farmateka [Pharmateca Journal] 2014; 3: 47-52.
  8. Chuchalin AG, Sinopal'nikov AI, Strachunskij LS, Kozlov RS, Rachina SA, Jakovlev SV. Vnebol'nichnaja pnevmonija u vzroslyh: prakticheskie rekomendacii po diagnostike, lecheniju i profilaktike [Community-acquired pneumonia in adults: practical recommendations for diagnosis, treatment and prevention]. Klinicheskaya mikrobiologiya i antimikrobnaya himoterapiya [Clinical Microbiology and Antimicrobial Chemotherapy] 2006; 8: 54–86.
  9. Nair GB, Niederman MS. Community-acquired pneumonia: an unfinished battle. Med Clin North Am. 2011; 956: 1143-1161.
  10. Pneumonia. In: European lung white book. 2nd ed.            Sheffield, UK: European Resiratory Society. European Lung Foundation. 2003; P. 55-65.

 

PDF downloadModern nutrition in patients with late onset asthma 

Goremykina Maria S., resident of the Department of family medicine of Samara State Medical university, Samara, Russia, tel. 8-917-824-07-79, e-mail: Goremykina_marya@mail.ru

Kupaev Vitalii I., D.Med.Sci., Professor, Head of the Department of family medicine of Samara State Medical University, Samara, Russia, tel. 8-927-256-09-27, e-mail: vk1964sam@rambler.ru

Sazonova Olga V., D.Med.Sci., associate professor, Institute of hygiene and human ecology of Samara State Medical University, Samara, Russia, tel. 9-901-335, e-mail: Ov_2004@mail.ru

Gorbachev Dmitriy O., C.Med.Sci., senior lecturer of the Department of general hygiene of Samara State Medical University, Samara, Russia, tel. 8-927-261-73-02, e-mail: dmitriy-426@rambler.ru

Yakunova Elena M., c.Med.Sci., leading researcher, institute of hygiene and human ecology of Samara State Medical University, Samara, Russia, tel. 8-903-303-45-23, e-mail: lena.my@mail.ru

Galitskaya Anna V., research officer (researcher), Institute of hygiene and human ecology of Samara State Medical University, Samara, Russia, tel. 8-917-818-11-82

  1. There are numerous researches relevant to genetic and environmental influences on asthma, but little is known about dietary risk factors in development of asthma. Aim. This study’s purpose was to analyze the actual nutrition of patients with late onset asthma. Material and methods. We studied 37 patients with late onset bronchial asthma. Age — 54 years (34—75), BMI — 32,1 kg/m2 (28,6—36,4).The control group consisted of 47 people without asthma only, and 44 persons without asthma but with metabolic syndrome. Subjects completed questionnaires by specifying the frequency and amount of food intake. Results. It is revealed that the diet of patients with bronchial asthma have less amounts of vitamins: А — 771,7 mcg, В1 — 0,6 mg, B2 — 1,02 mg, B3 — 9,9 mg, macroelements: Mg — 241,2 mg, Сa — 500,9 mg, P — 1085,9 mg, Fe — 12,2 mg, К — 2575,1 mg and polyunsaturated fatty acids — 9,23 g in comparison with the control group. Conclusions. Nutritional correction of the diet of patients with bronchial asthma should include sufficient amounts of vitamins and dietary fiber.

Key words: asthma, airway health, diet, adult, nutrition.

 

For reference: Goremykina MS, Kupaev VI, Sazonova OV Gorbachev DO, Yakunova EM, Galickaya AV. Modern nutrition in patients with late onset asthma. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 22—26.

 

References

  1. Avcyn AP, Zhavoronkov AA, Rish MA, Strochkova LS. Mikrojelementozy cheloveka: jetiologija, klassifikacija, organopatologija [Human microelementoses: etiology, classification, organophile]. M, 1991; 496.
  2. Ermolova AV, Budnevskij AV, Drobysheva ES. Bronhial'naja astma i metabolicheski jsindrom: kliniko-patogeneticheskie vzaimosvjazi [Bronchial asthma and metabolic syndrome: clinical and pathogenetic relationship]. Molodojuchenyj [young scientist]. 2014; 65 (6): 291-294.
  3. Goremykina MS, Kosmynina MA, Kupaev VI. Vlijanie vitamina D na genez bronhial'noj astmy v sochetanii s metabolicheskim sindromom[The effect of vitamin D in the Genesis of bron-
    chial asthma in combination with metabolic syndrome]. Izvestija Samarskogo nauchnogo centra Rossijskoj akademiinauk [Izvestiya Samara scientific center of the Russian Academy of Sciences]. 2014; 16: 5 (2): 776-778.
  4. Sazonova OV, Jakunova EM, Galickaja AV, Borodina LM. Ocenka pishhevogo statusa zhitelej Samary i Samarskoj oblasti [Assessment of nutritional status of residents of Samara and Samara region]/ Izvestija Samarskogo nauchnogo centra Rossijskoj akademii nauk [Izvestiya Samara scientific center of the Russian Academy of Sciences]. Samara 2014; 16: 5 (2): 940-942.
  5. Bueso AK, Berntsen S, Mowinckel P, Andersen LF, Carlsen KCL, Carlsen KH. Dietary intake in adolescents with asthma – potential for improvement. PediatrAllergy Immunology 2011; 22: 9–24.
  6. Nurmatov U, Devereux G, Sheikh A. Nutrients and foods for the primary prevention of asthma and allergy: systematic review and meta-analysis. J Allergy Clin Immun 2011; 127: 724–733.
  7. Schaub B, E. von Mutius. Obesity and asthma, what are the links? Curr. Opin. Allergy Clin. Immunol. 2005; 5: 185-193.
  8. Tricon S, Willers S, Smit H, Burney P, Devereux G, Frew AJ, Halken S, Host A, Nelson M, Shaheen S, Warner JO. Nutrition and allergic disease. Clin Exp Allergy Reviews 2006; 6: 117–188.
  9. Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG. Manipulating antioxidant intake in asthma: a randomized controlled trial. Am J Clin Nutr. 2012; 96: 534–543.
  10. Yueh-Ying Han, Josh Blatter, John M Brehm, Erick Forno, Augusto A Litonjua, Juan C Celedón. Diet and asthma: vitamins and methyl donors. Lancet Respir Med. 2013; 1: 813–822.

 

PDF downloadDevelopment of organizational and economic approaches for pharmacy manufacture of medicines (pharmacy № 361 of state enterprise «Tattechmedpharm» as the example) 

Tukhbatullina Ruzaliya G., D.Рharm.Sci., Head of the Department of pharmaceutical technology of Kazan State Medical University, Kazan, Russia, tel. 8(917)-266-45-66, e-mail: ruzaliyatuhbatullina@mail.ru

Davletova Golira R., 5-year student of the Department of pharmaceutical technology of Kazan State Medical university, Kazan, Russia, e-mail: golira.92@mail.ru

Galeeva Zulfiya M., pharmacist of the highest category, Head of Pharmacy №361 of State Enterprise «Tattechmedpharm», Kazan, Russia, e-mail: apt361.kzn@tatar.ru

  1. Aim. To develop organizational and economic approaches to pharmacy production of medicines. Material and methods. We analyzed the reports on the formulations of pharmacy №361 SUE «Tattehmedfarm» in 2011—2013. We studied the main financial indicators, prescription journals, laboratory and packing work, requirements of medical institutions, passports of control over 2011—2013 using methods of systemic, economic, retrospective, comparative analysis. Results and discussion. It has been established that the «direct costing» method of management can achieve high integration of accounting and analysis, management decision-making to optimize the prices of pharmacy manufacture of medicines, to minimize costs and maximize profits. Conclusion. Results of the study showed the feasibility of «direct costing» management accounting system in pharmacy organizations.

Key words: pharmacy, individually made medications, management accounting, direct costing.

 

For reference: Tukhbatullina RG Davletova GR, Galeeva ZM. Development of organizational and economic approaches for pharmacy manufacture of medicines (pharmacy №361 of state enterprise «Tattechmedpharm» as the example). The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 26—32.

 

References

  1. Tuhbatullina RG. Organizacionno-jekonomicheskoe obosnovanie povyshenija dostupnosti i kachestva lekarstvennoj pomoshhi naseleniju v Respublike Tatarstan: Avtoref dis na soisk uchen step k farm n : 15.00.01 [Organizational and economic justification for increasing the availability and quality of drugs to the population in the Republic of Tatarstan: author dis on competition exercises step K Pharm N: 15.00.01 ] . [Feder gos uchrezhdenie nauki — Nauch-issled in-t farmacii M-va zdravoohranenija Ros Federacii]. M. 2000; 24.
  2. Leont'eva FR. Razrabotka strukturno-funkcional'noj modeli gosudarstvennoj sistemy lekarstvennogo obespechenija naselenija Respubliki Tatarstan [Development of structural-functional model of the state system of drug provision of the population of the Republic of Tatarstan ]. Avtoref dis na soisk uchen step kand farm n: 15.00.01 / Leont'eva Farida Rizvanovna; [Pjatigorskaja gosudarstvennaja farmacevticheskaja akademija]. Pjatigorsk. 2004; 20.
  3. Dudarenkova MR, Gladunova EP. Analiz jekstemporal'nogo izgotovlenija lekarstvennyh sredstv v aptechnyh organizacijah analysis of the extemporaneous manufacture of medicinal products in pharmacies ]. Izvestija Samarskogo nauchnogo centra Rossijskoj akademii nauk. Special'nyj vypusk «III Vserossijskaja nauchno-prakticheskaja konferencija «Processy, tehnologija oborudovanie i opyt pererabotki othodov i vtorichnogo syr'ja» [Izvestiya Samara scientific center of the Russian Academy of Sciences. Special issue «of the III all-Russian scientific-practical conference «Processes, technology, equipment and experience in the waste and secondary raw materials»]. 2008; 122-125.
  4. Egorova S.N. Aptechnoe izgotovlenie: lekarstvennye formy, ne imejushhie promyshlennyh analogov [Pharmaceutical manufacturing: pharmaceutical form, not having an industrial counterparts ]. Novaja apteka [New pharmacy]. 2007; 6: 39-42.
  5. Tuhbatullina RG. «Direkt-kosting» instrument maksimizacii pribyli i minimizacii zatrat v apteke / R.G.Tuhbatullina [Direct-costing» tool to maximize profits and minimize costs in the pharmacy]. Novaja apteka [New pharmacy]. 2002; 5: 39-45.
  6. Tuhbatullina RG, Safiullin RS. Upravlencheskij uchet v sisteme upravlenija aptechnym uchrezhdeniem [Management accounting in the management system of the pharmacy institution]. Kazan': KGMU [Kazan: Kazan state medical University ]. 2001; 22.

 

PDF downloadInfluence of radio frequency electromagnetic radiation on the tissues of heart and vessels in the experiment 

Khamidova Gulozod M., сompetitor of the Department of Internal Medicine of Tashkent Institute of Postgraduate Medical Education, Tashkent, Uzbekistan, tel. +9(989)350-107-77, e-mail: gulozod@gmail.com

  1. Aim. To study the level of antigen-binding lymphocytes (ABL) to the tissue antigens (TA) of the pericardium, endocardium, myocardium, arteries and veins, as a prognostic criterion of extent and depth of the defeat of the cardiovascular system, depending on the different doses and exposure of radio frequency electromagnetic radiation (RF-EMR) exposition. Material and methods. An experimental study on 36 white rats, which were divided into 4 groups: 1, 2, and 3 experimental groups of 10 animals each with a capacity of influence RF-EMR 50 mW/cm2, 500 mW/cm2 and 1,000 mW/cm2, respectively. Group 4 — Control (6 animals), without affecting RF EMR. Results. The results of research immunocytochemical indicators ABL TA to heart tissue and blood vessels reflect the development of pathological processes in organs and systems of the living organism that occur even at low doses, and increases with increasing dose and confirmed by morphological study. Conclusions. ABL parameters for TA heart tissue and blood vessels can be used to assess the degree of destruction of them; it was confirmed by morphological studies relevant tissues. With increasing dose and duration of exposure RF-EMR in organs and tissues, occurs marked destructive changes of heart tissue and blood vessels, diagnostic and prognostic criterion of this may serve ABL TA.

Key words: lymphocyte antigen, tissue antigen, electromagnetic radiation, immunocytochemical and morphological studies.

 

For reference: Khamidova GM. Influence of radio frequency electromagnetic radiation on the tissues of heart and vessels in the experiment. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 32—36.

 

References

  1. Garib FJu, Gurarij NI, Garib VF. Sposob opredelenija subpopuljacij limfocitov. Rasmij ahborotnoma. 1995; 1: 90.
  2. Capri M, Scarcella E, Fumelli C et al. In vitro exposure of human lymphocytes to 900 MHz CW and GSM modulated radiofrequency: Studies of proliferation, apoptosis and mitochondrial membrane potential. Radiation Research. 2004; 162: 211-218.
  3. Zotti-Martelli L, Peccatori M, Maggini V et al. Individual responsiveness to induction of micronuclei in human lymphocytes after exposure in vitro to 1800-MHz microwave radiation. Mutation Res. 2005; 582: 42-52.

 

PDF downloadApplication of complex influence of several physiotherapy methods for increase of treatment efficacy in newly diagnosed destructive forms of pulmonary tuberculosis 

Khanin Arkady L., D.Med.Sci., Professor, Honoured doctor of the Russian Federation, Head of the Department of phthisiopulmonology of novokuznetsk State institute of Postgraduate Medical, novokuznetsk, Russia, tel. 8(903)-945-2252, e-mail: prof.khanin@yandex.ru

Pilnik Galina V., deputy chief physician of medical work of Prokopevsky tB dispensaries, Prokopyevsk, Russia, tel. 8(905)-068-34-57, e-mail: galinapilnik@yandex.ru

Nicotina Galina L., chief doctor of Prokopevsky tB dispensaries, Prokopyevsk, Russia, tel. 8(960)-907-67-69

  1. The aim of research — to compare the effectiveness of treatment of destructive, bacillary pulmonary tuberculosis in newly diagnosed patients treated with standard chemotherapy and in patients who used complex magnetic-infrared-laser therapy (MIL) on the background of standard treatment of tuberculosis and ultrasonic inhalations (UI) with the Contrykal. Material and methods. 180 patients with pulmonary TB were observed. This group were divided into three subgroups (45 patients in each): (1) patients received MIL-therapy on a background of standard chemotherapy, (2) standard treatment and UI with the Contrykal, (3) UI with the Contrykal and then MIL-therapy on the affected areas after 20 minutes; (4) comparison group, standard chemotherapy. Results and discussion. It was found that intoxication syndrome relief by the end of the first month was observed in 62,8% of patients of the first group, in 69% of patients in the second, 84,8% — third group and in comparison group — 40,6%. Abacillation of mucus (microscopy method of detection) after three months of treatment was observed in 93,3% of patients of the third group, 82,2% and 86,7% — in the first and second group respectively and 51,1% in comparison group. Decay cavities were eliminated after 6 months in 95,6% patients: 57,8%, — third, 77,7% — first and 28,9% — second group, comparison group — only 28,9%. Conclusion. Application of complex therapy enhances the effect of antibiotic treatment of destructive pulmonary tuberculosis due to the multi-faceted, complex effects on the main pathogenetic mechanisms of specific inflammation.

Key words: tuberculosis, complex physiotherapy, the effectiveness of treatment.

 

For reference: Khanin AL, Pilnik GV, Nicotina GL. Application of complex influence of several physiotherapy methods for increase of treatment efficacy in newly diagnosed destructive forms of pulmonary tuberculosis. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 36—42.

 

References

  1. Amirov NB. Mehanizmy terapevticheskogo lazernogo vozdejstvija v klinike vnutrennih boleznej (обзор) [Mechanisms therapeutic laser influence on internal medicine clinic (review)]. Kazanskij medicinskij zhurnal [Kazan Medical Journal]. 2001; 82 (5): 369-372.
  2. Amirov NB, Vizel АА, Oslopov VN. Jeffektivnost' terapii pnevmonii po dannym pokazatelej mikrocirkuljacii i koncentracii mikrojelementov v syvorotke krovi [Pneumonia effectiveness of therapy according to indicators of microcirculation and concentration of trace substances in blood serum]. Zhurnal mezhdunarodnoj mediciny — Pediatrija [International Medical Journal — Pediatrics]. 2013; №2 (3): 96 -99.
  3. Vasil'eva IА, Taran DV. Proekt po sboru i izucheniju luchshih primerov organizacii lechenija i klinicheskogo vedenija bol'nyh s mnozhestvennoj lekarstvennoj ustojchivost'ju vozbuditelja tuberkuleza i sochetannym s VICh-infekciej [The project according to the collecting and studying of the best examples of the organization of treatment and clinical maintaining patients with MDR-TB and HIV-infection. Problemy tuberkuljoza i boleznej ljogkih [Problems of tuberculosis and lung diseases]. 2014; 1: 3 -6.
  4. Balasanjanc GS. Jeffektivnost' primenenija ul'trazvukovogo obluchenija selezjonki u bol'nyh ostroprogressirujushhim tuberkuljozom ljogkih [Efficiency of application of ultrasonic radiation of a lien for patients with an acute progress pulmonary tuberculosis]. Problemy tuberkuljoza [Problems of tuberculosis]. 2002; 6: 24-30.
  5. Levashov AN, Kir'yanova VV, Vinogradov TI. Vlijanie diodnogo izluchenija s dlinoj volny 470 nm na jeffektivnost' lechenija bol'nyh tuberkuljozom ljogkih [Effect of diode radiation with a wavelength of 470 nm on the effectiveness of treatment of patients with pulmonary tuberculosis]. Fizioterapija, bal'neologija, reabilitacija [Physiotherapy, balneology, rehabilitation]. 2008; 4: 15-18.
  6. Mrozova ТI. Jeffektivnost' himioterapii v sochetanii s ingibitorami proteoliza u bol'nyh infil'trativnym tuberkuljozom ljogkih v faze raspada [Efficiency of a chemotherapy in combination with proteolysis inhibitors at patients with an infiltrative destructive pulmonary tuberculosis]: avtoref. Med. Sci. PhD diss., 1986; 24 р.
  7. Nechaeva ОB, Biragova ОК. Jepidemicheskaja situacija po tuberkuljozu v RF [Epidemic TB situation in the Russian Federation]// Soc. Associacija Zdorov'ja naselenija [Soc. Association of public health] [Electron. resource]. 2013; 5 (33). URL: http://vestnik/mednet.ru/content/view/514/27/lang.ru.
  8. Ovsyankina ES, Dobkin VG, Firsov VA et al. Lazeroterapija v kompleksnom lechenii tuberkuljoza ljogkih u podrostkov: Posobie dlja vrachej [Laser therapy in the complex treatment of pulmonary tuberculosis in adolescents: A Manual for Physicians]. Problemy tuberkuljoza i boleznej ljogkih [Problems of tuberculosis and lung diseases]. 2005; 1: 56-61.
  9. Parmon EM, Barshcheuski VS, Kamyshnikov VS. Kombinirovannoe nizkointensivnoe lazernoe izluchenie pri tuberkuljoze pochek [Combined low-intensity laser radiation when renal tuberculosis]. Problemy tuberkuljoza i boleznej ljogkih [Problems of tuberculosis and lung diseases]. 2003; 6: 28-33.
  10. Pilnik GV, Khanin АL, Nicotina GL. Jeffektivnost' kompleksnoj terapii bol'nyh tuberkulezom legkih s primeneniem sovremennyh fizioterapevticheskih metodov [Efficiency of complex therapy of patients with a pulmonary TB with use of modern physiotherapeutic methods]. Cb. materialov nauchno-prakticheskoj konferencii. «Medicina 21 veka» [Coll. of materials of scientific and practical conference «Medicine of 21 centuries»]. Novokuznetsk, 2015: 102-103.
  11. Fizioterapija: nacional'noe rukovodstvo [Physiotherapy: national leadership]. ed GN Ponomarenko. M: GEOTAR Media, 2009. 864 p.
  12. Khanin AL, Long SA. Vlijanie mediko-social'nyh faktorov riska na jeffektivnost' lechenija vpervye vyjavlennyh bol'nyh tuberkulezom [Effect of medical and social risk factors on the effectiveness of the treatment of newly diagnosed TB patients]/ Sb. materialov mezhdunarodnoj nauchno-prakticheskoj konferencii «Social'no — znachimye bolezni». [Proc. International scientific-practical conference «Socio — significant diseases»]. Kemerovo, 2004: 55-57.
  13. Hudzik LB, Morozova ТI. Proteolitichekie sistemy krovi u bol'nyh tuberkuljozom ljogkih [Proteolytic system of blood at Patient with pulmonary TB]. Problemy tuberkuljoza [Problems of tuberculosis]. 1994; 5: 56-58.
  14. Chastnaja fizioterapija / uchebnoe posobie [Private physiotherapy / textbook]. ed GN Ponomarenko. M: «Medicine», 2005; 744.
  15. Best practices in prevention, control and care for drug-resistant tuberculosis. WHO, EURO, Copengagen, 2013. JSBN — №9789289000468.

 

PDF downloadClinical-pathogenetic reasoning of multimodal analgesia adequacy in peryoperative period in long-termed traumatic abdominal operative interventions 

Sharipova Visolat Kh., C.Med.Sci., Сhief of the Department of anesthesiology and operational block in Republic research center of emergency medicine (RRCEM), Tashkent, Uzbekistan, tel.: (998-71)-150-46-10, (998-71)-150-46-00, fax: (998-71)-150-46-05, e-mail: visolat_78@mail.ru

  1. Application of epidural analgesia in combination with general anesthesia promotes a smooth course of intra- and post-operative periods with the minimal tension of hemodynamic indexes and reduced pain symptomatic in post-operative period. It has the economic effect shown up as the decrease narcotic analgetics prescription both in intra- and post-operative periods. Aim. Improvement methods of perioperative multimodal analgesia in long and traumatic abdominal operative interventions with estimation of its efficiency. Material and methods. 86 patients has been examined and divided into 3 groups depending on anesthesia and postoperative pain relief ways. Results. Revealed the efficiency of perioperative multy-modal analgesia affected the pathogenesis of pain in long and traumatic abdominal operative interventions based on central and peripheral hemodynamics indexes study. Conclusion. A scheme of perioperative multimodal analgesia in long and traumatic abdominal operative interventions developed.

Key words: multi-modal analgesia, pain, epidural block.

 

For reference: Sharipova VKh. Clinical-pathogenetic reasoning of multimodal analgesia adequacy in peryoperative period in long-termed traumatic abdominal operative interventions. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 42—49.

 

References

  1. Ovechkin AM, Morozov DV, Jarkov IP. Obesbolivanie i sedatsiya v posleoperationnom periode: realii i vozmojnosti [Pain-relieve and sedation in post-operative period: reality and possibility]. Vestnik intensivnoy terapii [Intensive Care Bulletin]. 2001; 4: 47-60.
  2. Acute Pain Management: Scientific Evidence. Australian and New Zeland College of Anaesthetists, 2-nd edition, 2005 (endorsed Royal College of Anaesthetists, UK); 310.
  3. Bolivar M, Bolivar A, Vargas G. Multimodal postoperative analgesia with nonsteroidal anti-inflammatory drugs and the epidural hematoma “myth”. Book Abstr 9th World Congress on Pain, Vienna, Austria, 1999; 439.
  4. Cousins M. Acute and postoperative pain. In Wall P.and Melzack R. (eds). Textbook of Pain, 3dn, Philadelphia, Churchill-Livingstone, 2004; P. 357-385.
  5. Dolin S, Cashman J, Bland J. Effectiveness of acute postoperative pain management: I. Evidence from published data. Br J Anaesth. 2002; 89: 409-423.
  6. Fu E, Miguel R, Scharf J. Preemptive ketamine decreases postoperative narcotic requirements in patients undergoing abdominal surgery. Anesth Analg. 1997; 84: 1086-1090.
  7. Kehlet H, Holte K. Effect of postoperative analgesia on surgical outcome. Br J Anaesth. 2001; 87: 62-72.
  8. Menigaux C, Guignard В, Fletcher D. Intraoperative small-dose ketamine enhances analgesia after outpatient knee arthroscopy. Anesth Analg. 2001; 93: 606-612.
  9. Postoperative Pain Management – Good Clinical Practice. General recommendations and principles for successful pain management. Produced with the consultations with the Europeans Society of Regional Anaesthesia and Pain Therapy. Project chairman N Rawal, 2005; 57.

 

Experience Exchange

PDF downloadExperience of treatment maxilla fractures and deformations by laboratory manufactured splints 

Raff Alla I., C.Med.Sci., associate professor of the Department of prosthodontics and general dentistry of Kazan State Medical Academy, Russia, Kazan, tel. 9-904-662-42-28, e-mail: ralla1@rambler.ru

  1. The aim of research. To conduct clinical assessment of functional treatment techniques of maxilla injuries and deformities by laboratory manufactured splints with metal spring-loaded elements. To study the possibility of its shape deformation necessary to move the jaw fragments in transversal, sagittal and vertical plane. Material and methods. An analysis of 9 cases of difficult fracture consolidation and reposition of broken maxilla with impossibility of traditional treatment was performed. Results and discussion. Demonstrated that functional treatment of fractures with mobile springy planes transporting fragments of a broken jaw in sagittal, transversal and vertical planes provides the necessary therapeutic effect and speed up the healing process. Combined forms of pathology treated with the same transforming splint reduce treatment time with no need to replace it. Conclusion. Bactericidal nitridide titan gafnium nanocoating 2—5 microns provides additional therapeutic effect in the treatment of pathologies maxilla due to the properties of the coating affecting the microflora of the mouth.

Key words: ion-plasma coating, tooth-gingival splint.

For reference: Raff AI. Experience of treatment maxilla fractures and deformations by laboratory manufactured splints. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 50—52.

 

References

  1. Bajrikov IM. Sravnitel'naja ocenka metodov lechenija bol'nyh s perelomami nizhnej cheljusti i ih kliniko-funkcional'noe obsledovanie [Comparative evaluation of methods of treatment of patients with mandibular fractures and their clinical and functional examination]: avtoref dis kand med nauk: 14.01.14; Kalinin: Kalinin, 1987; 17.
  2. Dmitrieva VS. Perelomy nizhnej cheljusti (ne ognestrel'nye) i ih lechenie: uchebnoe posobie [Mandibular fractures (not gunshot) and their treatment: a tutorial]. M: Un-t Druzhby Narodov, 1984; 84 .
  3. Kuroedov VD, Grigor'eva LP, Siryk VA. Izmenenija v zhevatel'nyh myshcah visochno-nizhnecheljustnom sustave i okolozubnyh tkanjah pri mezial'nom peremeshhenii nizhnej cheljusti v jeksperimente [Changes in masticatory muscles temporomandibular joint and periodontal tissues in the mesial movement of the lower jaw in the experiment]. Kaz Vesti St. 1995; 1: 15-17.
  4. Nazubnaja shina: pat A.S.№1678354 SSSR:MPK4 A61 K 31/21, A 61 P 23/02. [Tooth Splint]/ Kulagin, V.M., Malevich, O.E., Emel'janov, G.I. zajavitel' i patentoobladatel' GOU VPO «Dnepropetrovskij medicinskij institut». - № 4746408/14; zajavl. 03.10.1989; opubl. 23.09.1991, Bjul. №35. – 2 р.
  5. Studenikina FG, Mironov MM, Denisov VP et al. Issledovanie antimikrobnyh svojstv nekotoryh metallov i pokrytij dlja medicinskih izdelij [Investigation of antimicrobial properties of some metals and coatings for medical devices]. sb. «Medicinskaja tehnika»: Moskva, 1993; 5: 6-8.
  6. Shina dlja lechenija perelomov al'veoljarnogo otrostka verhnej cheljusti: pat. 2290146 Ros. Federacija: MPK8 A61 K 31/21, A 61 P 23/02. [Splint for the treatment of fractures of the alveolar process of maxilla]/ Abdullin, I.Sh., Mironov, M.M., Raff, A.I., Jamashev, I.G. zajavitel' i patentoobladatel' GOU VPO «Kazanskij gosudarstvennyj tehnologicheskij universitet». - № 2005111501; zajavl. 18.04.2005; opubl. 27.12.2006, Bjul. № 36. – 4 р.
  7. Shina dlja lechenija perelomov tela verhnej cheljusti: pat. 56170 Ros. Federacija: MPK8 A61 K 31/21, A 61 P 23/02.[Splint for the treatment of fractures of the body of the maxilla]/ Abdullin, I.Sh., Mironov, M.M., Raff, A.I., Jamashev, I.G. zajavitel' i patentoobladatel' GOU VPO «Kazanskij gosudarstvennyj tehnologicheskij universitet». - № 2005111500; zajavl. 18.04.2005; opubl. 10.09.2006, Bjul. № 25. – 4 р.
  8. Jamashev IG, Raff AI. Nazubno-desnevye shiny dlja lechenija perelomov cheljustej [Tooth-gingival splints for the treatment of fractures of the jaws]. Akt. voprosy cheljustno-licevoj hirurgii i stomatologii [Topical issues of Maxillofacial Surgery and Dentistry]. S.Peterburg, 1997; 66-67.

 

Help For Practitioner

PDF downloadFunctional method of temporomandibular joint dysfunction treatment 

Raff Alla I., C.Med.Sci., associate professor of the Department of prosthodontics and general dentistry of Kazan State Medical Academy, Russia, Kazan, tel. 9-904-662-42-28, e-mail: ralla1@rambler.ru

  1. Aim. To conduct and evaluate the procedure of the functional treatment of temporomandibular joint dysfunctions. Material and methods. The analysis of treatment of 20 patients with temporomandibular joint disorders occured in connection with violations of the bite and teeth. Therefore it became necessary to create the constructions that would solve the problem to eliminate the causes that create this kind of disease. Results and discussion. Demonstrated that the application of spring elements allows move the teeth simultaneously, which leads to disruption of occlusal relations of vertical, sagittal and transversal planes, and an effective therapeutic result and cure of this disease. It is important to note the fact that the devices for treatment of the temporomandibular joint dysfunctions are made individually, according to the existing pathology. Conclusion. Bactericidal coating provides additional therapeutic effect in the treatment of temporomandibular joint dysfunctions due to the properties of the coating.

Key words: corrosion resistance of ion-plasma coating, treatment of dysfunctions of the temporomandibular joint.

For reference: Raff AI. Functional method of temporomandibular joint dysfunction treatment. The Bulletin of
Contemporary Clinical Medicine. 2015; 8 (4): 53—55.

 

References

  1. Borovskij EV, Leont'ev VK. Biologija polosti rta [Oral Biology]. «Medicina»: Moskva. 1991; 83-85.
  2. Egorov PM, Puzin MN, Kushlinskij NE. Miofascial'nyj bolevoj sindrom lica [Myofascial face pain syndrome]. M: Iz-vo Rossijskogo Universiteta Druzhby Narodov; 1991. 48 p.
  3. Mirza AI. Diagnostika i osnovnye napravlenija v lechenii bolevogo sindroma disfunkcii visochno-nizhnecheljustnogo sustava [Diagnosis and main trends in the treatment of pain dysfunction of the temporomandibular joint]. M: «Sovremennaja stomatologija».1999; 187-190.
  4. Puzin MN, Shubina OS, Marulidi RG. Biopovedencheskaja terapija rasstrojstva visochno-nizhnecheljustnogo sustava [Biobehavioral therapy disorders of the temporomandibular joint]. M: «Rossijskij stomatologicheskij zhurnal» . 2001; 1: 23-25.
  5. Raff AI. Opyt ortopedicheskogo lechenija bol'nyh s cheljustno-licevoj patologiej [Practice orthopedic treatment of patients with maxillofacial pathology].Vestnik sovremennoj klinicheskoj mediciny [The Bulletin of Contemporary Clinical Medicine]. 2015; 8 (3): 25-28.
  6. Ustrojstvo dlja lechenija disfunkcij visochno-nizhnecheljustnogo sustava: pat. 87079 Ros. Federacija: MPK8 A61 K 31/21, A 61 P 23/02. [The device for the treatment of Temporomandibular joint dysfunction] / Abdullin I.Sh., Raff A.I., Shajmieva N.I. zajavitel' i patentoobladatel' GOU VPO «Kazanskij gosudarstvennyj tehnologicheskij universitet». — № 2009121042; zajavl. 2.06.2009; opubl. 27.09.2009, Bjul. № 35. — 4 р.
  7. Ustrojstvo dlja lechenija disfunkcij visochno-nizhnecheljustnogo sustava: pat. 88935 Ros. Federacija: MPK8 A61 K 31/21, A 61 P 23/02. [The device for the treatment of Temporomandibular joint dysfunction]/ Abdullin, I.Sh., Raff, A.I., Shajmieva, N.I. zajavitel' i patentoobladatel' GOU VPO «Kazanskij gosudarstvennyj tehnologicheskij universitet». — № 2009121043; zajavl. 2.06.2009; opubl. 27.11.2009, Bjul. № 26. — 4 р.

 

Reviews

PDF downloadImmune disorders in children with atopic dermatitis combinated with chronic diseases 

Davletbaeva Giuzel R., pediatrician of Childrens Republican Clinical Hospital, Kazan, Russia, tel. +7(917)-392-87-37, e-mail: davletbaeva.giuzel@yandex.ru

  1. Aim. Analysis the current data on combination of atopic dermatitis and chronic (including inflammatory) diseases in children. Material and methods. A review of domestic and foreign publications, devoted to immune disorders in children with atopic dermatitis combinated with chronic inflammatory diseases. The current view of the pathophysiological mechanisms of combination of allergic diseases with inflammatory diseases was analyzed. Results and discussion. During the analysis of the literature founded significant correlation between allergic and inflammatory diseases. Particular attention is paid to childhood atopic dermatitis in combination with chronic gastroduodenitis, hypovitaminosis of vitamin D, connective tissue dysplasia, mental disorders. Conclusion. Analysis of the problem of combined atopic dermatitis with chronic inflammatory diseases justifies the need for further study. The findings can serve as a basis for the development of new treatments.

Key words: atopic dermatitis, chronic gastroduodenitis, vitamin D, connective tissue dysplasia, mental disorders.

For reference: Davletbaeva GR. Immune disorders in children with atopic dermatitis combinated with chronic diseases. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 56—64.

 

References

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  3. Varlamov EE, Pampura AN.Znachenie filaggrina v razvitii atopicheskogo dermatita [The value of filaggrin in the development of atopic dermatitis]. Rossijskij allergologicheskij zhurnal [Russian Allergy zhurnal]. 2011; 5: 26-30.
  4. Halovit EA, Galova EA, Sazanova NE. Novye mehanizmy patogeneza hronicheskogo gastroduodenita u detej doshkol'nogo vozrasta (immunologicheskie aspekty) [New mechanisms of pathogenesis of chronic gastroduodenitis in children of preschool age (immunological aspects)] / // Klinicheskaja medicina [Clinical medicine].2010; 1: 49-55.
  5. Goryunova MM, Petrovsky AN, Melnikov IY. Osobennosti formirovanija hronicheskogo gastroduodenita u detej s atopicheskim dermatitom [Features of formation of chronic gastroduodenitis in children with atopic dermatitis]. Klinicheskaja gastrojenterologija [Clinical Gastroenterology]. 2010; 1: 137-140.
  6. Davletbaeva GR. Recidivirujushhie infekcii mochevyh putej u detej s atopicheskim dermatitom [Recurrent urinary tract infections in children with atopic dermatitis]. Sbornik nauchnyh trudov po itogam mezhdunarodnoj nauchno-prakticheskoj konferencii «Problemy mediciny v sovremennyh uslovijah» [Collection of scientific papers on the results of the international scientific-practical conference «Problems of medicine in modern conditions»]. Kazan. 2014: 132-134.
  7. Denisov M, Kaznacheeva LF. Strategija patogeneticheskoj terapii pri zabolevanijah organov pishhevarenija u detej s atopicheskimi zabolevanijami i ocenka ee jeffektivnosti [Strategy pathogenetic therapy in diseases of the digestive system in children with atopic diseases and evaluation of its effectiveness]. Allergologija [Allergology]. 2002; 3: 46-53.
  8. Znamenskaya LK. Sostojanie mikrobiocenoza kishechnika u pacientov s atopicheskim dermatitom v zavisimosti ot stepeni tjazhesti zabolevanija [Microbiocenosis bowel in patients with atopic dermatitis, depending on the severity of the disease]. Tavricheskij mediko-biologicheskij vestnik [Tauride Medical and Biological vestnik]. 2013; 16 (1): 3 (61): 80-82.
  9. Ilina NI, Fedoskova TG.Rol' allergicheskih zabolevanij v obshheklinicheskoj praktike [The role of allergic diseases in general clinical practice]. Russkij medicinskij zhurnal [Russian Medical Journal].2004; 4: 876-879.
  10. Karpov EB, Chemodanov VV. Pokazateli mikrovjazkosti jeritrocitov u bol'nyh atopicheskim dermatitom na fone soedinitel'notkannoj displazii [Indicators microviscosity of erythrocytes in patients with atopic dermatitis during the connective tissue dysplasia]. Vestnik Ivanovskoj medicinskoj akademii [Bulletin of the Ivanovo Medical Academy]. 2007; 12 (1-2): 91-92.
  11. Keniksfest YuV. Zabolevaemost' atopicheskim dermatitom detej i podrostkov v Ural'skom, Sibirskom i Dal'nevostochnom federal'nyh okrugah [The incidence of atopic dermatitis children and adolescents in the Urals, Siberian and Far Eastern Federal Districts]. Vestnik dermatologii i venerologii [Journal of Dermatology and Venereology]. 2011; 4: 8-13.
  12. Korotkij NG, Tihomirov AA, Taganov AV et al. Atopicheskij dermatit u detej [Atopic dermatitis in children] . Tver': Triada. 2003: 238 р.
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  18. Sentsova TB, Denisova SN, Belitskaya MYu. Osobennosti citokinovogo statusa u detej rannego vozrasta s atopicheskim dermatitom [Features cytokine status in infants with atopic dermatitis]. Rossijskij allergologicheskij zhurnal [Russian Journal of Allergy]. 2011; 6:
    33-41.
  19. Tour II, Savenkova ND, Nazarov PG et al. Sravnitel'noe issledovanie IgE-antitel, IFN -ɣ i IL-4 u detej s nefroticheskim sindromom s minimal'nymi izmenenijami i atopicheskim dermatitom [A comparative study of IgE-antibodies, IFN -ɣ and IL-4 in children with nephrotic syndrome with minimal changes and atopic dermatitis] . Nefrologija [Nefrology]. 2007; 4: 69-74.
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PDF downloadDiagnosis and treatment the diabetic comas according to recent recommendations of the management of patients with diabetes mellitus 

Maiorova Elena M., C. Med. Sci., associate professor of the Department of therapy of Kazan State Medical Academy, tel. (843)-236-21-70, e-mail: lena2912@list.ru

Garipova Alsu F., assistant of professor of the Department of therapy of Kazan State Medical Academy, tel. (843)-236-21-70, e-mail: garalsu@bk.ru

  1. The aim of research — analysis of the diagnostic and treatment of diabetes mellitus comas according to the latest guidelines and algorithms for the management of patients with diabetes mellitus. Material and methods. We reviewed diabetic ketoacidosis, hyperosmolar nonketotic and hypoglycemic comas. Results and discussion. We described the etiology, mechanisms and stages of development of these states. Described complaints, clinical and laboratory data of patients with diabetic ketoacidosis precoma. A clinical picture of diabetic comas presented. Disclosed the issues of laboratory diagnostics. Particular attention is paid to the treatment of patients in a coma according to the latest guidelines and algorithms for the management of patients with diabetes mellitus. Conclusions. The conception of diagnosis and treatment of diabetic comas constantly changing, so is particularly important to review and analyze the new recommendations and algorithms of management of patients with diabetes mellitus.

Key words: diabetes mellitus, diabetic ketoacidosis, hyperosmolar nonketotic coma, hypoglycemic coma.

For reference: Maiorova EM, Garipova AF. Diagnosis and treatment the diabetic comas according to the recent recommendations of the management of patients with diabetes mellitus. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 64—68.

 

References

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PDF downloadRespiratory support of patients in acute period of subarachnoid hemorrhage 

Shpaner Roman Ya., Head of the Department of anesthesiology and intensive care unit 3 of Interregional clinic-diagnostic center, associate professor of the Department of anesthesiology and critical care medicine, disaster medicine of Kazan State Medical University, Kazan, Russia, tel. 8(917)-927-85-28, e-mail: rshp@bk.ru

  1. Aim. Analysis of recent publications on the problem of mechanical ventilation in patients with subarachnoid hemorrhage was performed. Material and methods. A review of recent years devoted to the subject. Results and discussion. Implementation of mechanical ventilation is one of the components in the provision of intensive care in intensive care units. Indications for mechanical ventilation in patients with and without brain damage are different. Patients with severe brain damage need to have a special approach to respiratory support. Presented the modern principles of respiratory support in patients with acute subarachnoid hemorrhage. The selection of optimal parameters and regimens that are used during mechanical ventilation were presented. Conclusions. In patients with subarachnoid hemorrhage conducting adequate respiratory support, if necessary, (depression of consciousness to coma), is required and it is essential part of intensive care complex. Ensuring adequate oxygen demand improves outcome.

Key words: subarachnoid hemorrhage, anapnotherapy.

For reference: Shpaner RYa. Respiratory support of patients in acute period of subarachnoid hemorrhage. The Bulletin of Contemporary Clinical Medicine. 2015; 8 (4): 68—73.

 

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