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СОNTENTS

ORIGINAL ARTICLES

Questionnaire survey of the social and hygienic stomatologic status of citzens of tatarstan republic. A.K. Salakhov, E.M. Silagadze, R.F. Baykeev, S.S. Ksembayev, M.V. Ovechkina. P. 7-11

Opinion of clients of private ophtalmologic clinics about patient’s rights. D.A. Lipinski, M.Y. Abrosimova. P. 11-15

Condition of vegetative nervous system in patients with atopic dermatitis. O.I. Aksenova, V.N. Marchenko, K.N. Monakhov. P. 15-18

Drug addiction, HIV-infection, tuberculosis. Features of multi-comorbidity in modern conditions. E.A. Borodulina, I.L. Tsygankov, B.E. Borodulin, E.S. Vdoushkina, E.V. Borodulina. P. 18-22

Diagnostic methods of sistemic osteoporosis in psychiatric patients. R.Yu. Iljina, L.R. Mukhamedzhanova. P. 22-26

Potential of ultrasound in dermal neoplasms diagnostic. I.V. Klyushkin, Ju.A. Klyushkina. P. 26-30

Optimisation of treatment reactive arthritis patients. M.G. Nogayeva. P. 30-33

Contamination by parodontopatogenic oral microflora in patients with parkinson's disease. G.R. Ruvinskaya, L.R. Mukhamedzhanova, M.S. Mommaeva. P. 33-37

About prevention of psychological consequences in military personnel located in radiation hazard zone. P.A. Suin, D.A. Zemlyannikov. P. 37-42

The possibility to predict the course of hospitalization period of acute coronary syndrome with immune inflammation markers. M.A. Shalenkova, E.T. Manyukova, Z.D. Mikhailova, P.F. Klimkin. P. 42-46

Physical rehabilitation for COPD. L.A. Ergeshova. P. 46-49

The frequency of dyslipidemia in HIV-patients and its correlation with markers of microbial translocation and inflammation. G.R. Khasanova.49- 53

REVIEWS

Practice of antibacterial treatment for community acquired pneumonia. From the literature review to own data. G.V. Lysenko. P. 53-58

DISCUSSION

Definition of the health concept within the bounds of quality of life study in dental patients. N.S. Fyodorova, R.A. Saleev. P. 58-63

HELP FOR PRACTITIONER

Diagnosis and treatment of sarcoidosis. Summary of Federal Conciliative Clinical Recommendations. Part I. Classification, etiopathogenesis, clinic. A.G. Chuchalin, A.A. Vizel, M.M. IlkovIch, S.N. Avdeev, N.B. Amirov, O.P. Baranova, S.E. Borisov, I.Yu. Vizel, O.V. Lovacheva, N.V. Ovsyannikov, D.V. Petrov, V.V. Romanov, M.V. Samsonovа, I.P. Solovyova, I.E.Stepanian, I.E. Tyurin, A.L. Cherniayev, E.I. Shmelev, N.M. Shmeleva. P. 63-71

WHEN THE ISSUE WAS IN PRESS

Behavioral regulation level of tobacco smokers. O.A. Sukhovskaya, S.S. Ivanova, M.A. Smirnova. P. 71-75

________

ORIGINAL STUDIES

Questionnaire survey of the social and hygienic stomatologic status of citzens of Tatarstan Republic

Albert K. Salakhov, candidate of medical sciences, assistant to chair of maxillofacial surgery of SBei HPe «Kazan State Medical university» of Ministry of Health of russia, Kazan, russia, tel. 8-903-342-78-18, e-mail: albert-salahov@yandex.ru

Elena M. Silagadze, competitor of chair of stomatology of children's age of SBei HPe «Kazan State Medical university» of Ministry of Health of russia, Kazan, russia, tel. 8-903-313-30-99, e-mail: silok@list.ru

Rustem F. Baykeev, doctor of medical sciences, professor of chair of biochemistry of SBei HPe «Kazan State Medical university» of Ministry of Health of russia, Kazan, russia, tel. 8-905-314-11-76, e-mail: baykeev@mail.ru
Said S. Ksembayev, the doctor of medical sciences, professor of chair of stomatology of children's age of SBei HPe «Kazan State Medical university» of Ministry of Health of russia, Kazan, russia, tel. 8-905-020-68-86, e-mail: ksembaev@rambler.ru

Maria V. Ovechkina, the candidate of medical sciences, the doctor of clinic of Plasmoclinic, Kazan, russia, tel. 8-926-539-83-58, e-mail: ovechckina-maria@ynadex.ru

Abstract. Aim. To investigate the stomatologic status of citizens of Tatarstan according to city/village (3/1) distribution and to develop technology on prediction dental fillings loss on the 1 year. Material and methods.Atotalof772persons(random sampling) 238 men (30,87%) and 533 women (69,13%) at the age of 20—79 years and 20—82 years respectively were interrogated. Kazan citizens (572 persons) and Tatarstan villagers (200 people) participated in research as respondents. In our work, we used specially developed author's questionnaire consisting of 25 points with subparagraphs, covering the main aspects of activity of the person. We used descriptive statistics and the discriminant analysis. As informative indicators we used classification accuracy (number of the respondents described by the corresponding equation) and value of conanial function as criterion of dental fillings loss prediction. Results. Demonstrated that citizens of RT regions had better individual hygiene of an oral cavity. They visit the stomatologist more often; manage preventive measures for the prevention of caries, give preferences to foreign toothpastes, toothbrushes and light-setting dental fillings. However, the tooth brushing regularity, fluoration of teeth and correct diet with restriction of consumption of easily fermented carbohydrates are characteristic for residents of Kazan. The technology of forecasting of safety of seals on term in 59,1% of cases is developed 1 year.

Key words: questioning, predicting loss fillings, dental hygiene and social status.

 

References

1. Silagadze, E.M. Social'no-gigienicheskii stomatologicheskii status zhitelei goroda Kazani [Social and hygienic stomatologic status of residents of Kazan] / E.M. Silagadze, A.K. Salahov, R.F. Baikeev, S.S. Ksembaev // Obschestvennoe zdorov'e i zdravoohranenie [Public Health and Health Care]. — 2010. — № 2. — S.32—36.
2. Axelsson, P. Diagnosis and Risk Prevention of Dental Caries / P. Axelsson // Quintessence Publishing Co, Inc. — 2000. — Vol. 2.— P.7—36.
3. Barnett, E.D. For the GeoSentinel Surveillance Network. Spectrum of IIIness in Internacional Migrants Seen at GeoSentinel Clinics in 1997—2009. Part 1: US-Bound Migrants Evaluated by Comprehensive Protocol-Based Health Assessment / E.D. Barnett, L.H. Weld, A.E. McCarthy [et al.] // Clin. Infect. Dis. — 2013. — Vol. 56(7). — P.913—924.
4. Garton, B. Root caries: a survey of Queensland dentists / B. Garton, P. Ford // Int. J. Dent. Hyg. — 2013. — Vol. 11(3). — P.216—225.
5. Kaur, A. Evaluation of non-microbial salivary caries activity parameters and salivary biochemical indicators in predicting dental caries / A. Kaur, K.S. Kwatra, P. Kamboj // J. Indian. Soc. Pedod. Prev. Dent. — 2012. — Vol. 30(3). — P.212— 307.
6. Kramer, P.F. Exploring the impact of oral diseases and disorders on quality of life of preschool children / P.F. Kramer, C.A. Feldens, S. Helena Ferreira [et al.] // Community Dent. Oral. Epidemiol. — 2013. — Vol. 41. — P.327—235.
7. Lampert, L.M. Limited evidence for preventing childhood caries using fluoride supplement s/ L.M. Lampert, D. Lo // Evid. Based. Dent. — 2012. — Vol. 13(4). — P.112—203.
8. Mai, X. Associations between smoking and tooth loss according to the reason for tooth loss: The Buffalo OsteoPerio Study/ X. Mai, J. Wactawski-Wende, K.M. Hovey [et al.] // J. Am. Dent. Assoc. — 2013. — Vol. 144(3). — P.252—365.
9. Nakonieczna-Rudnicka, M. Selected risk factors for diseases of hard tooth tissues in tobacco smokers-preliminary study / M. Nakonieczna-Rudnicka, T. Bachanek // Przegl. Lek. — 2012. — Vol. 69(10). — P.756—809.
10. Sudhir, R. Assessment of the effect of probiotic curd consumption on salivary pH and streptococcus mutans counts / R. Sudhir, P. Praveen, A. Anantharaj [et al.] // Niger. Med. J. — 2012. — Vol. 53(3). — P.135—209.

 

Opinion of clients of private ophtalmologic clinics about patient’s rights

Dmitri A. Lipinski, Нead doctor of ltd. Medical research center «the third eye+», competitor the Department of biomedicine, medical law and medical history of SBei HPe «Kazan State Medical university», Kazan, russia, tel. 8-917-296-11-91, e-mail: biopravo@yandex.ru

Marina Y. Abrosimova, doctor of medical science, professor, head the Department of biomedicine, medical law and medical history of SBei HPe «Kazan State Medical university», Kazan, russia, tel. 8-904-670-56-78, e-mail: marabro@yandex.ru

Abstract. Aim. The purpose of the research was to study awareness and opinion of clients of private ophtalmologic clinic about patient’s rights and their observance during the process of medical care. Material and methods. By the method of anonymous survey, we interviewed 108 patients who were seeking medical care. Results and discussion. In most cases, patients received information about their rights in health care sphere from their doctor, but only in a half of cases, the information has been provided in an accessible and understandable form. Even less patients were informed about the responsibility of health workers for damage to the patient’s health during medical intervention. Private clinics clients signed consent often didn’t read it because of the small font of the document, a large amount of the text and lack of time to study its contents, which are quite avoidable causes. Not all interviewed respondents recognize the need of abidance of medical confidentiality in ophtalmic practice and the patient’s consent to disclose information about his health to third parties. Conclusion. Significant proportion of patients (45,4%) are not ready to relationship model between physician and patient based on the principle of cooperation, preferring to trust implicity in the knowledge and experience of the doctor.

Key words: patient’s rights, ophthalmic care, private medicine.

 

References

1. Ivanyushkin, A.Ya. Istoriya i etika sestrinskogo dela [History and ethics nursing business] / A.Ya. Ivanyushkin, A.K. Hetagurova. — M.: GOU VUNMC MZ RF, 2003. — 320 s.
2. Litvinov, A.N. Kontrol' kachestva medicinskoi pomoschi i obespechenie prav pacienta [Quality control of medical care and ensuring rights of patient] / A.N. Litvinov, A.S. Fuks // Byulleten' GU NNII obschestvennogo zdorov'ya RAMN. — 2007. — Vyp. 2. — S.84—88.
3. Togunov, I.A. K voprosu ob evolyucii vzaimootnoshenii vracha i pacienta v otechestvennoi sisteme zdravoohraneniya [To a question of evolution of relationship of the doctor and the patient in domestic health system] / I.A. Togunov // Upravlenie zdravoohraneniem: organizaciya, planirovanie, ekonomika: materialy nauch.-prakt. konf., 14—15 noyab. 2000 g., Moskva // Byulleten' NII SGE i UZ im. N.A. Semashko. — M., 2000. — S.76—81.
4. Federal'nyi zakon ot 21.11.2011 № 323-FZ «Ob osnovah ohrany zdorov'ya grazhdan v RF» s kommentariyami yuristov kompanii «Garant» [The federal law of November 21, 2011 No. 323-FZ «About bases of health protection of citizens in the Russian Federation» with comments of lawyers of the Garant company]. — M.: Eksmo, 2012. — 160 s.
5. Filatov, V.N. Udovletvorennost' klientov kachestvom platnoi medicinskoi pomoschi v gosudarstvennyh uchrezhdeniyah zdravoohraneniya ambulatornogo zvena [Customer satisfaction with the quality of paid medical care in public health facilities outpatient] / V.N. Filatov, O.A. Mahova // Menedzher zdravoohraneniya [Manager of health care]. — 2006. — № 7. — S.30—36.
6. Filippov, Yu.N. Pravo pacienta na avtonomiyu v zakonodatel'stve RF [The patient's right to autonomy in the legislation of the Russian Federation] / Yu.N. Filippov, O.P. Abaeva. — M.: Miklosh, 2010. — 64 s.

 

Condition of vegetative nervous system in patients with atopic dermatitis

Olga I. Aksenova, the senior laboratory assistant of chair of a dermatovenereology with clinic SBei HPe «Pavlov State Medical university of St. Petersburg» of Ministry of Health of the russian federation, St. Petersburg, russia, tel. 8-905-275-96-32, e-mail: akseonova_olga@mail.ru

Valery N. Marchenko, MD, professor of chair of hospital therapy with an allergology and immunology course of M.V.chernorutsky with clinic SBei HPe «Pavlov State Medical university of St. Petersburg» of Ministry of Health of the russian federation, St. Petersburg, russia

Konstantin N. Monakhov, MD, professor of chair of a dermatovenereology with clinic SBei HPe «Pavlov State Medical university of St. Petersburg» of Ministry of Health of the russian federation, St. Petersburg, russia

Abstract. Aim. The purpose of our study was to estimate condition of vegetative nervous system in patients with atopic dermatitis by spectral analysis of the variability of heart rhythm (VHR). Material and methods. The method allows to evaluate the activity of both sympathetic and parasympathetic parts of vegetative nervous system (VNS) concerning to heart rhythm regulation. Functional tests with adjustable mode of breathing display reserve regulatory abilities of VNS. A total of 45 patients having atopic dermatitis took part in research. 267 healthy volunteers were examined as a control group. Results. Patients with atopic dermatitis demonstrated the initial heterogeneity on indicators of sympathovagalis balance: normo- and sympathico-tonia prevailed. Breathing tests of patients with atopic dermatitis detected relative functional deficiency of sympathetic and parasympathetic parts of VNS. Conclusion. Spectral analysis of the variability of heart rhythms using functional tests allows estimate quantitatively not only a vegetative orientation, but also reserve regulatory abilities of each parts of VNS.

Key words: vegetative nervous system, variability of heart rhythm, atopic dermatitis.

 

References

1. 1. Monakhov, K.N. Funkcional'naya aktivnost' vegetativnoi nervnoi sistemy pri atopicheskom dermatite [Functional activity of vegetal nervous system at atopic dermatitis] / K.N. Monakhov, V.L. Poleschuk // Zhurnal dermatovenerologii i kosmetologii [Dermatovenereology and cosmetology magazine]. — 2003. — № 1. — S.10—13.
2. Atopicheskii dermatit: rekomendacii dlya prakticheskih vrachei // Rossiiskii nacional'nyi soglasitel'nyi dokument po atopicheskomu dermatitu [Russian national conciliatory document on atopic dermatitis] / pod red. akad. RAMN R.M. Haitova, prof. A.A. Kubanovoi. — M.: Farmarus Print, 2002. — 192 s.
3. Grebenyuk, V.N. Atopicheskii dermatit kak termin i zabolevanie [Atopic dermatitis as term and disease] / V.N. Grebenyuk, V.G. Akimov // Vestnik dermatologii i venerologii [Messenger of dermatology and venereology]. — 1992. — № 8. — S.47—49.
4. Potockii, I.I. Neirodermit [Neurodermatitis] / I.I. Potockii. — Kiev, 1986. — 215 s.
5. Balabolkin, I.I. Atopicheskii dermatit u detei [Atopic dermatitis at children] / I.I. Balabolkin, V.N. Grebenyuk. — M.: Medicina, 1999. — 240 s.
6. Sergeeva, Yu.V. Atopicheskii dermatit [Atopic dermatitis] / Yu.V. Sergeeva. — M.: Medicina dlya vseh [Medicine for all], 2002. — 234 s.
7. Ruksin, V.V. Standartizaciya i monitorirovanie pokazatelei variabel'nosti serdechnogo ritma [Standardization and monitoring of indicators of variability of a heart rhythm] / V.V. Ruksin, V.V. Pivovarov, V.H. Kudashev, E.I. Fedchenko // Terramedica. — 1998. — № 1. — S.2—7.
8. Marchenko, V.N. Mehanizmy neirovegetativnoi regulyacii kardiorespiratornoi sistemy u bol'nyh bronhial'noi astmoi i puti korrekcii vyyavlennyh narushenii: avtoref. dis. ... d-ra med. nauk [Mechanisms of neurovegetative regulation of cardiorespiratory system at patients with bronchial asthma and ways of correction of the revealed violations. The thesis abstract on competition of a scientific degree of the doctor of medical sciences] / V.N. Marchenko. — SPb., 2004. — 38 s.
9. Marchenko, V.N. Ocenka vegetativnoi nervnoi sistemy u bol'nyh atopicheskim dermatitom metodom analiza variabel'nosti serdechnogo ritma [Estimates of vegetative nervous system at patients with atopic dermatitis with a method of the analysis of variability of a heart rhythm] / V.N. Marchenko, K.N. Monahov, V.L. Poleschuk, A.V. Savich // Allergologiya. — 2002. — № 4. — S.11—13.

 

Drug addiction, hiv-infection, tuberculosis. Features of multi-comorbidity in modern conditions

Elena A. Borodulina, Igor L. Tsygankov, Boris E. Borodulin, Elizaveta S. Vdoushkina, Elvira V. Borodulina

Abstract. The purpose of this work is to reflect the problem of comorbidity of tuberculosis, HIV and drug addiction in one patient. The features of TB/HIV in people who use drugs accessed. This group of patients has been jailed 2,5 times more likely, 79,8% were not working, and 20% were homeless. Tuberculosis often took with a high-grade clinical picture, disseminated tuberculosis and multiple organ failure and systems were dominating. Adherence to antiretroviral therapy (ART) was 17%, this patients 3 times more likely to discontinue therapy, AIDS were three times more likely. During the observation period in the group TB/HIV drug users, 78% died, which is 3 times more than in the TB/HIV, who were not taking drugs. Tuberculosis among HIV-infected drug users is a problem not only phthisiology but more likely society problem.

Key words: tuberculosis, HIV infection, drug addiction.

 

References

1. Shilova, M.V. Tuberkulez v Rossii v 2011 godu: monografiya [Tuberculosis in Russia in 2011: monography] / M.V. Shilova. — M., 2013. — S.188—191.
2. Frolova, O.P. Tuberkulez u bol'nyh VICH-infekciei kak nacional'naya problema [Tuberculosis in HIV-infected patients as a national problem] / O.P. Frolova, V.A. Polesskii, O.A. Novoselova [i dr.] // Tuberkulez i bolezni legkih [Tuberculosis and Lung Diseases]. — 2013. — № 10. — S.9—12.
3. Shovkun, L.A. Tuberkulez legkih u VICH-inficirovannyh pacientov: klinicheskie proyavleniya i korrelyaciya s koefficientom SD4/SD8 [Pulmonary tuberculosis in HIVinfected patients: clinical manifestations and the correlation coefficient with SD4/SD8] / L.A. Shovkun, N.E. Romanceva, A.V. Konstantinova // Allergologiya i immunologiya [Allergology and immunology]. — 2006. — № 3. — S.303.
4. Borodulin, B.E. Tuberkulez u VICH-inficirovannyh v krupnom promyshlennom centre [Tuberculosis in HIV-infected patients in a large industrial center] / B.E. Borodulin, E.A. Borodulina, I.I. Kulikova [i dr.] // Pul'monologiya [Pulmonology]. — 2007. — № 2. — S.56—59.
5. Cygankov, I.L. Epidemiologiya tuberkuleza v gorode s vysokim rasprostraneniem VICH-infekcii [Epidemiology of tuberculosis in the city with the highest HIV infection] / I.L. Cygankov, O.E. Chernova, E.A. Borodulina // Aktual'nye problemy i perspektivy razvitiya protivotuberkuleznoi sluzhby v Rossiiskoi Federacii: materialy I Kongressa Nacional'noi associacii ftiziatrov [Actual problems of development prospects of TB services in the Russian Federation Proceedings 1st Congress of the National Association phthisiologists] / pod red. P.K. Yablonskogo. — 2012. — S.76—77.

 

Diagnostic methods of sistemic osteoporosis in psychiatric patients

Roza Yu. Iljina, candidate of medical sciences, assistant of maxillofacial surgery and surgical stomatology department of SBei HPe «Kazan State Medical Academy», Kazan, russia, tel. 8-917-255-43-87, ilroza@yandex.ru

Lubov R. Mukhamedzhanova, doctor of medical science of stomatological diseases and new technology department of fSBei HPe «chuvash State university», cheboksary, russia, tel. 8-965-597-11-64, е-mail: lr71@bk.ru

Abstract. Aim. To examine the bone density in psychiatric patients by two various methods. Matherials and methods. 104 psychiatric patients undergone ultrasound and biochemical markers of bone metabolism. Results. Osteoporosis found in 25% cases and osteopenia at 33,7%. This is 1,5 exceed the level of healthy people at the same age and it’s not corresponded the prevalence of osteoporosis in average population. Assessment of bone resorbtion biochemical markers confirmed efficiency of ultrasound attenuation. Patients with osteoporosis had high blood levels of pyridinoline, tartrat-resistant acidic phosphatase and sRANKL in comparison patients with normal bone density. Conclusion. In this research accuracy and comparability of both methods demonstrated and using them for diagnostic of osteoporosis and osteopenia recommended.

Key words: osteoporosis, osteopenia, psychiatric patients, ultrasound attenuation, biochemical bone markers.

 

References

1. Nasonov, E.L. Problemyosteoporoza:izucheniebiohimicheskih markerov kostnogo metabolizma [Problem of osteoporosis: research biochemical markers of bone metabolism] / E.L.Nasonov // Klinicheskaya medicina [Clinical medicine].— 1998. — № 5. — S.20—25.
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3. Riggz Lorens, B. Osteoporoz. Etiologiya, diagnostika, lechenie [Osteoporosis. Etiology, diagnosis, treatment] / B. Riggz Lorens, L.Dzh. Melton; pod obsch. red. prof. E.A Leparskogo. — M.: Binom, 2000. — 560 s.
4. Delmas, P.D. Utility of biochemical markers in osteoporosis / P.D. Delmas // Osteoporosis; eds. R. Marcus [et al.]. — New York, 1996. — P.1075—1088.
5. Eriksen, E.F. New markers of bone metabolism: clinical use in bone disease / E.F. Eriksen, K. Brixen, P. Charles // Europ. J. of Endocrinol. — 1995. — Vol. 132. — P.251—263.
6. Heaney, RP. Osteoporotic bone fragility: detection by ultrasound transmission velocity/ R.P. Heaney // JAMA. — 1989. — № 261. — P.2986—2990.
7. Hummer, M.P. Osteoporosis in patients with schizophrenia / M.P. Hummer, W. Malik, M.D. Rudolf // American J. of Psychiatry. — 2005. — № 162. — P.162—167.
8. Kishimoto, T. Antipsychotic-induced hyperprolactinaemia inhibits the hypothalamo-pituitary-gonadal axis and reduces bone mineral in male patients with schizophrenia/T.Kishimoto // J. Clin. Psychiatry. — 2008. — № 69(3). — P.385—391.
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10. Massic, A. Screening for osteoporosis: comparison between dual energy x-ray absorptiometry and broadband ultrasound attenuation in 1000 perimenopausal women / A. Massic // Osteoporosis Int. — 1993. — № 3. — P.107—110.
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13. Roux, J.P. Automated interactive measurement of resorbtion cavities in transiliac bone biopsies and correlation with deoxypyridinoline/J.P.Roux,M.E.Arlot,E.Gineyts//Bone.— 1995. — Vol. 17. — P.153—156.

 

Potential of ultrasound in dermal neoplasms diagnostic

Ivan V. klyushkin, doctor of medicine, professor of chair of the general surgery of SBei HPe «Kazan State Medical universiti» of Ministry of Health of russia, Kazan, russia, tel. 8-919-624-96-40, e-mail: hirurgivan@rambler.ru

Julia A. Klyushkina, candidate of medical sciences, ultrasonographer of unit of diagnostics of GAuz GKB № 7 of Kazan, assistant to chair of ultrasonic diagnostics of SBei APe «Kazan State Medical Academy» of Ministry of Health of russia, Kazan, russia, tel. 8-919-625-68-25, e-mail: klyushkina_1974@mail.ru

Abstract. Aim. Research objective — to use the combined ultrasound for diagnostic and the differentiated approach to patients with skin new growths. Problem of medical tactics in patients with skin new growths, despite their superficial arrangement, causes many questions among clinical physicians, dermatologists and oncologists. Most of these patients consult in outpatient medical organizations. Material and methods. 39 ambulatory patients from 20 to 67 years, with cosmetic defect and feeling of discomfort in area of skin new growths are surveyed. Results and discussion. Demonstrated that ultrasound allows visualizing with big degree of reliability the size, structure of new growths, its borders and germination in nearby tissues. We estimated pathological processes in the soft tissues of new growth. This processes being accompanied with regionary blood-flow changes, type of vessels changes, and existence or absence of vascularisation. Received information of vessels, allows to determine benign or malignancy processes in a new growth. Nearby tissue changes shows possible inflammatory post-traumatic and infectious components of pathological process. Conclusion. We analyzed ultrasound semiotics of most often skin new growths: a pigmentary nevus, tumors from sebaceous glands, dermatofibromas, skin fibromas and vascular tumors. The most patognomic signs are produced to make the correct decision in a choice of medical tactics. Information on a type of the blood supply, received at ultrasound allows to correct treatment tactics in time. The undoubted advantages of ultrasound are availability, possibility of polyposition survey and a assessment of a vascularisation without contrast. For scanning it is necessary to use superficial high-frequency sensors.

Key words: skin, new growths, ultrasound, blood supply, ultrasound sensors.

 

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4. Zubarev, A.R. Ul'trazvukovoe issledovanie opornodvigatel'nogo apparata u vzroslyh i detei: posobie dlya vrachei / A.R. Zubarev, N.A. Nemenova. — M.: Vidar-M, 2006. — 136 s.
5. Kaminskaya, I.V. Ul'trazvukovaya tomografiya v kompleksnoi diagnostike zlokachestvennyh opuholei myagkih tkanei tulovischa i konechnostei u detei / I.V. Kaminskaya, N.A. Koshechkina // Detskaya onkologiya. — 2004. — № 3/4. — S.19—25.
6. Klyushkina, Yu.A. Ul'trazvukovaya vizualizaciya dermal'nyh obrazovanii: ucheb.-metod. posobie dlya vrachei, aspirantov, ordinatorov, internov, studentov starshih kursov medicinskih vuzov / Yu.A. Klyushkina, I.V. Klyushkin. — Kazan': ID MedDok, 2013. — 28 s.
7. Kurbanova, A.A. Kozhnye bolezni: rukovodstvo dlya vrachei i studentov medicinskih vuzov / A.A. Kurbanova. — M.: GEOTAR-Medicina, 1998. — 178 s.
8. Pugacheva, E.N. Vozmozhnosti kompleksnoi ul'trazvukovoi vizualizacii dobrokachestvennyh myagkotkanyh obrazovanii stopy i golenostopnogo sustava / E.N. Pugacheva, I.V. Varakuta, L.V. Koryshkova // Ul'trazvukovaya i funkcional'naya diagnostika: tezisy VI S'ezda RASUDM. — 2011. — № 5. — S.99.
9. Opti, Dzh. Ul'trazvukovoe issledovanie / Dzh. Opti, E. Houi, S. Vul'stenhul'm [i dr.]; per. s angl. pod red. V.A. Sandrikova. — M.: GEOTAR-Media, 2010. — 256 s.
10. Skripkin, Yu.K. Kozhnye i venericheskie bolezni: rukovodstvo dlya vrachei i studentov medicinskih vuzov / Yu.K. Skripkin. — M.: Triada-farm, 2001. — 656 s.
11. Tuhbatullin, M.G. Sovremennye ul'trazvukovye tehnologii v klinicheskoi praktike / M.G. Tuhbatullin, I.M. Alieva // Prakticheskaya medicina. — 2012. — № 5(60). — S.30 — 35.
12. Fedorova, I.V. Sovremennye vozmozhnosti sonografii v differencial'noi diagnostike opuholei myagkih tkanei / I.V. Fedorova, I.G. Frolova // Sibirskii onkologicheskii zhurnal. — 2004. — № 1. — S.49—50.
13. Fatyhov, R.I. Primenenie ul'trazvukovyh metodov diagnostiki pri vybore sposoba lecheniya sindroma  «diabeticheskoi stopy» / R.I. Fatyhov, I.V. Klyushkin // Transfuziologiya XXI veka: problemy, zadachi, perspektivy razvitiya: Mezhdunar. nauch.-prakt. konf. po organizacionnym i klinicheskim razdelam v transfuziologii; «Den' transfuziologa». — Kazan', 2013. — S.170—172.

 

Optimisation of treatment reactive arthritis patients

Maral G. Nogayeva, PhD., the acting lecturer of faculty outpatient therapy Kazakh national Medical university named after S.D. Asfendiyarov, Almaty city, е-mail: maral.nogaeva@mail.ru

Abstract. Aim. The purpose — to study the efficacy and safety of herbal drug Kanefron®N in the complex treatment of patients with reactive arthritis. Material and methods. The study included 47 patients with ReA aged 18 — 44 years (men), mean age — 26,01±0,86. Patients were divided into two groups: I group (n —27) was obtained etiotropicantibiotic therapy Kanefron®N at a dose of 2 tablets 3 times a day for three months, and nonsteroidal anti-inflammatory drugs (NSAIDs), short-course (Ksefokam at a dose of 8 mg for 7 days per os), II group (n — 20) — antibiotics and NSAIDs short courses (Ksefokam 8 mg for 7 days per os). Results. In the first group of patients treated with Kanefron®N showed a significant decrease (p<0,05) leukocyturia, bacteriuria, and better subjective health assessment in comparison with the second. The normalization of the microflora of urine (I group) was noted at the 2th, and in the II group on the 4th week of treatment. The study revealed the major pathogens — ureaplasma in 40% of cases, and their various combinations with bacterial agents in 25%. Conclusion. The findings suggest that Kanefron®N has antimicrobial and anti-inflammatory action in complex therapyin regard to urinogenous ReA.

Key words: reactive arthritis, urethritis, antibiotic therapy, Kanefron®N.

 

References

1. Agababova, E.R. Kriterii reaktivnyh artritov (proekt) / E.R. Agababova, N.V. Bunchuk, S.V. SHubin [i dr.] // Nauchnaya prakticheskaya revmatologiya. — 2003. — № 3. — S.82—83.
2. Asner, T.V. Urogennye reaktivnye artrity: sovremennye aspekty diagnostiki i lecheniya / T.V. Asner, A.N. Kalyagin // Sovremennaya revmatologiya. — 2010. — № 4. — S.11—15.
3. Babaeva, A.R. Farmakoterapiya artritov, associirovannyh s urogenital'nymi infekciyami / A.R. Babaeva // Antibiotiki i himioterapiya. — 2010. — T. 48, № 3. — S.30.
4. Bermagambetova, G.N. Zdorov'e naseleniya Respubliki Kazahstan i deyatel'nost' organizacii zdravoohraneniya / G.N. Bermagambetova, R.G. Brozovskaya, A.K. Bekzhanova [i dr.] // Statisticheskii sbornik. — Astana; Almaty, 2010. — S.17—19.
5. Zherebkin, V.V. Reaktivnye artrity / V.V. Zherebkin // Bolezni i antibiotiki. — 2012. — № 1(6). — S.14—17.
6. Lokshin, K.L. Puti sovershenstvovaniya antimikrobnoi terapii uretrita u muzhchin / K.L. Lokshin, V.V. Rafal'skii, S.V. Korolev // Vrach. — 2008. — № 6. — S.41—45.
7. Revmatologiya: nacional'noe rukovodstvo / pod red. akad. RAMN E.L. Nasonova, akad. RAMN V.A. Nasonovoi. — M., 2010. — 720 c.
8. Ceban, E. Effektivnost' kompleksa travy zolototysyachnika, kornya lyubistoka i list'ev rozmarina (kanefron®N) pri mochekamennoi bolezni / E. Ceban // Zhurnal dlya fitoterapii. — 2012. — T. 1, vyp. 33. — S.19—23.
9. Combination antibiotics as a treatment for chronic Chlamydiainduced reactive arthritis / J.D. Carter, L.R. Espinoza, R.D. Inman [et al.] // Arthritis and Rheumatism. — 2010. — Vol. 62, iss. 5. — P.1298—1307.

 

Contamination by parodontopatogenic oral microflora in patients with parkinson's disease

Guzel R. Ruvinskaya, PhD, Assistant Professor of Department of therapy pediatric and orthodontic dentistry
of Kazan State Medical Academy, Kazan, Russia, tel. 8-917-278-98-34, e-mail: guzelruv@mail.ru

Lubov R. Mukhamedzhanova , MD, Professor of Department of propaedeutic dentistry and new technology
of Chuvash State University, Cheboksary, Russia, e-mail: lr71@bk.ru

Meriam S. Momaeva, biologist clinico-diagnostic laboratory of Republican Clinical Oncology Center,
Kazan, Russia, e-mail: m.mery@list.ru

Abstract. Aim — to explore the range of dominant conditionally pathogenic microorganisms in oral cavity microflora in patients with Parkinson's disease. Material and methods. We analyzed the qualitative composition of parodontopatogenic microflora of the oral cavity in 38 patients with Parkinson's disease by PCR diagnostics. Results and discussion. Found that the dominant microflora of periodontal pockets were bacteria of the genus Tannerella forsythensis (sown in 73,6% of cases), the incidence of Prevotella intermedia and Porphyromonas gingivalis was 63,2%, Acinobacillus actinomycetemcomitans — 60,5%, revealed less often (and only in the associations with 3—5 bacteria), Treponema denticola — in 55,3% of cases. A positive correlation in «periodontal pocket depth» and «frequency of the isolation of microbial strains parodontopatogennyh» (r=0,785) demonstrated.

Key words: Parkinson's disease, parodontopatogenic microflora status of periodontal tissues, PCR diagnostics.

 

References

1. Gavrilova, O.A. Mikroekologiya polosti rta i ee rol' v epiopatogeneze stomatologicheskih zabolevanii u detei s hronicheskim gastroduodenitom: principy kompleksnogo lecheniya i profilaktiki: avtoref. dis. ... d-ra med. nauk [Microecology of the oral cavity and its role in epiopatogeneze dental disease in children with chronic gastroduodenitom: principles of integrated treatment and prevention. Dr. Medicine sci. Diss] / O.A. Gavrilova. — Tver', 2010. — 48 s.
2. Grudyanov, A.I. Zabolevaniya parodonta [Periodontal disease] / A.I. Grudyanov. — M.: MIA, 2009. — 336 s.
3. Grudyanov, A.I. Metody diagnostiki vospalitel'nyh zabolevanii parodonta: rukovodstvo dlya vrachei [Methods of diagnosis of inflammatory periodontal diseases: Guide for Physicians] / A.I. Grudyanov, O.A. Zorina. — M.: MIA, 2009. — 112 s.
4. Zalyalova, Z.A. «Zolotoi standart» terapii bolezni Parkinsona [«The gold standard» treatment of Parkinson's disease] / Z.A. Zalyalova // Prakticheskaya medicina [Practical Medicine]. — 2009. — № 6(38). — S.136—138.
5. Zalyalova, Z.A. Nastoyaschee i buduschee okazaniya pomoschi bol'nym s ekstrapiramidnymi zabolevaniyami v g. Kazani [The present and the future to help patients with extrapyramidal disorders in the city of Kazan] / Z.A. Zalyalova, E.I. Bogdanov, L.V. Zabustova, G.R. Latypova // Nevrologicheskii vestnik [Neurological herald]. — 2007. — T. XXXIX, vyp. 4. — S.91—93.
6. Matisova, E.V. Kolonizaciya uslovno-patogennymi mikroorganizmami slizistoi obolochki polosti rta pri hronicheskom parodontite: avtoref dis. ... kand. med. nauk [Colonization of opportunistic infections of the oral mucosa in chronic periodontitis: Dr. Medicine sci. Diss] / E.V. Matisova. — Volgograd, 2010. — 46 s.
7. Lebedev, D.V. Mikrobiocenozy polosti rta u bol'nyh generalizovannym parodontitom, sposob diagnostiki i korrekcii: avtoref. dis. ... kand. med. nauk [Microbiocenoses oral cavity in patients with generalized periodontitis, the method of diagnosis and correction: Dr. Medicine sci. Diss] / D.V. Lebedev. — M., 2011. — 25 s.
8. Ruvinskaya, G.R. Osobennosti stomatologicheskoi kuracii pacientov s bolezn'yu Parkinsona [Features dental followup of patients with Parkinson's disease] / G.R. Ruvinskaya, Z.A. Zalyalova // Rossiiskii stomatologicheskii zhurnal. — 2012. — № 6. — S.30—32.
9. Carev, V.N. Parodontopatogennaya mikroflora polosti rta i principy antibakterial'nogo lecheniya / V.N. Carev. — M., 2008. — 81 s.
10. Berezow, A.B. Microbial shift and periodontitis / A.B. Berezow, R.P. Darveau // Periodontology. — 2011. — Vol. 55. — P.36—47.
11. Cloud, L.J. Gastrointestinal features of Parkinson's disease / L.J. Cloud, J.G. Greene // Curr. Neurol. Neurosci Rep. — 2011. —Vol. 11(4). — P.379—84.
12. Dexter, D.T. Parkinson disease from pathology to molecular disease mechanisms / D.T. Dexter, P. Jenner// Free Radic. Biol. Med. — 2013. — Vol. 62. — P.132—144.
13. Oral microflora and periodontal disease: new technology for diagnosis in dentistry / F. Carinci, L. Scapoli, A.Girardi [et al.] // Ann. Stomatol. (Roma). — 2013. — Vol. 4(2). — P.170—173.
14. Fritsch, T. Parkinson disease research update and clinical management / T. Fritsch, K.A. Smyth, M.S. Wallendal [et al.] // South Med. J. — 2012. — Vol. 105(12). — P.650—656.
15. Gazewood, J.D. Parkinson disease: an update / J.D. Gazewood, D.R. Richards, K. Clebak // Am. Fam. Physician. — 2013. — Vol. 15, № 87(4). — P.267—273.
16. Mineoka, T. Site-specific development of periodontal disease is associated with increased levels of Porphyromonasgingivalis, Treponema denticola, and Tannerella forsythia in subgingival plaque / T. Mineoka, S. Awano, T. Rikimaru [et al.] // J. Periodontol. — 2008. — Vol. 79. — P.670—676.
17. Noyce, A.J. Meta-analysis of early nonmotor features and risk factors for Parkinson disease / A.J. Noyce, J.P. Bestwick, L. Silveira-Moriyama [et al.] // Ann. Neurol. — 2012. — Vol. 72(6). — P.893—901.
18. Savage, A. A systematic review of definitions of periodontitis and methods that have been used to identify this disease / A. Savage, K.A. Eaton, D.R. Moles, I. Needleman // J. Clin. Periodontol. — 2009. — Vol. 36. — P.458—467.
19. Sauerbier, A. Non-motor symptoms: the core of multi-morbid Parkinson's disease / A. Sauerbier, K. Ray Chaudhuri // Br. J. Hosp. Med. (Lond). — 2013. — Vol. 8, № 75(1). — P.18—24.
20. Scapoli, L. Microflora and periodontal disease / L. Scapoli, A. Girardi, A. Palmieri [et al.] // Dent. Res. J. (Isfahan). — 2012. — Vol. 9(2). — Р.202—206.

 

About prevention of psychological consequences in military personnel located in radiation hazard zone

Pavel A. Suin, candidate of medical science, chief of branch, Moscow, Russia, tel. 8-906-783-17-33, e-mail: paul-s@bk.ru

Dmitryi A. Zemlyanikov, hospital chief, Lesnoy city of Sverdlovsk Region, Russia, tel. 8-963-674-20-64,
e-mail: semljannikov@mail.ru

Abstract. Arm. To determine the need of psychological consequences prophylaxis of military personnel exposed in an area of high radiation danger. Material and methods. Data on morbidity and labor losses of working population in the Gomel region of Belarus before the Chernobyl accident and after the accident. Results. In the first years after the accident, the growth of mental disorders in the population of the affected areas increase up to 2,5 times. Hypertension, gastric ulcer and duodenal ulcer increased up to 15—35% number of cases. Labor losses of the working population in these nosologies increased by 15—50%. A survey revealed that population productivity decreased by 20—30%, associated with declining health due to stay in the contaminated areas. Conclusions. In suffered individuals psychosomatic illnesses and various mental disorders can occur, most of them need psychological help. Persons with symptoms of emotional and behavioral disorders, different forms of neuropsychiatric diseases, located in the zone of radioactive contamination, medical and psychological correction should be carried out in a timely manner.

Key words: radiation danger, functional state, posttraumatic stress reactions, psychological consequences, ionizing radiation.

 

References

1. Gus'kova, A.K. Kliniko-epidemiologicheskaya harakteristika nablyudeniya za rabochimi predpriyatii atomnoi promyshlennosti Rossii, prinimavshimi uchastie v likvidacii posledstvii avarii na CHAES [Clinikal and epidemiological characteristics of surveillance of the working nuclear industry of Russia, took part in the aftermath of the Chernobyl accident] / A.K. Gus'kova, A.R. Tukov, G.N. Gasteva [i dr.] // Mediko-psihologicheskie posledstviya avarii na Chernobyl'skoi AES i puti ih preodoleniya: sb. tr. konf., SPb., 18—20 aprelya 1996 [Medical and psychological consequences of the Chernobyl accident and ways to overcome them. Conference Proceedings, St.-Peterburg, April 18-20, 1996]. — SPb.: Korona-print, 2002. — S.43—49.
2. Ivashkin, V.T. Organizaciya terapevticheskoi pomoschi priavariyah na ob'ektah yadernoi energetiki [Organization of therapeutic aid in case of accidents at nuclear facilities] / V.T. Ivashkin, Yu.K. Grigor'ev // Voenno-medicinskii zhurnal [Military Medical Journal]. — 1991. — № 9. — S.16— 20.
3. Krasnov, V.N. Terapiya psihicheskih rasstroistv u likvidatorov posledstvii avarii na CHAES [Treatment of mental disorders in liquidators of the Chernobyl accident] / V.N. Krasnov, M.M. Yurkin, V.V. Kryukov, N.Ya. Kurmysheva // Medikobiologicheskie i social'no-psihologicheskie problemy v chrezvychainyh situaciyah [Medico-biological and psychosocial problems in emergencies]. — 2010. — № 2. — S.15—20.
4. Patologiya otdalennogo perioda u likvidatorov posledstvii avarii na Chernobyl'skoi AES [Pathology remote period in liquidators of the Chernobyl accident] / pod red. prof. A.M. Nikiforova. — SPb.: Binom, 2002. — 304 s.
5. Prikaz Ministerstva zdravoohraneniya RF «O vvedenii v deistvie Rukovodstva po organizacii sanitarno-gigienicheskih i lechebno-profilakticheskih meropriyatii pri krupnomasshtabnyh radiacionnyh avariyah» ot 24 yanvarya 2000 g. № 20 [Order the Minister of Health the Russian Federation «On introduction of the guidelines for the organization of sanitary and preventive measures in large-scale radiation accidents» January 24, 2000, Vol. 20].
6. Rumyanceva, G.M. Vozmozhnosti ekspertnoi ocenki vreda psihicheskomu zdorov'yu lic, podvergshihsya nekontroliruemomu vozdeistviyu ioniziruyuschei radiacii [Scope of expertise harm the mental health of persons exposed to ionizing radiation uncontrolled] / G.M. Rumyanceva, O.V. Chinkina, S.N. Shishkov, E.YA. Schukina // Medicina kriticheskih sostoyanii [Critical care medicine]. — 2010. — № 2. — S.39—45.
7. Rybakova, T. L'got bol'she net [Benefits no longer] / T. Rybakova // Izvestiya. — 2004. — 1 sent. — S.12.
8. Timoshevskii, A.A. Medicinskaya protivoradiacionnaya zaschita specialistov avariino-spasatel'nyh formirovanii [Medical radiation protection specialist rescue units] / A.A. Timoshevskii, N.M. Kalinina, A.N. Grebenyuk, V.V. Zacepin // Mediko-biologicheskie i social'no-psihologicheskie problemy v chrezvychainyh situaciyah [Medico-biological and psychosocial problems in emergencies]. — 2008. — № 4. — S.13—18.

 

The possibility to predict the course of hospitalisation period of acute coronary syndrome with immune inflammation markers

Maria A. Shalenkova, MD, consultant, Municipal Clinical hospital № 38, N. Novgorod city, Russia, tel. 8-920-050-63-53, e-mail: mshalenkova@yandex.ru

Elvira T. Manyukova, doctor, Municipal Clinical hospital № 38, N. N ovgorod city, Russia, tel. 8-930-803-48-88, e-mail: elwira.manyukova@yandex.ru

Zinaida D. Mikhailova, PhD, consultant, Municipal Clinical hospital № 38, N. N ovgorod city, Russia, tel. 8-930-803-48-88, e-mail: zinaida.mihailowa@yandex.ru

Pavel F. Klimkin, doctor, Municipal Clinical hospital № 38, N. Novgorod city, Russia, tel. 8-920-058-19-86, e-mail: climckin2009@yandex.ru

Abstract. The purpose of the study is to define the role of immunoinflammatory reactions in predicting possible ACS
development during hospital stay period. Matherial and methods. We studied the following biomarkers: C-reactive protein (hs-CRP), natriuretic peptide (NTproBNP), interleukin-6 (IL-6), interleukin-10 (IL-10) in the blood and IL-6, IL-10 in the saliva of the patients with acute coronary syndrome (ACS) (n=173) and stable angina (SA) (n=57) during 1—3 days of hospitalization. Results. There has been identified a high hs-CRР and IL-6 levels in the blood of the patients suffering from ACS in comparison with SA patients. A higher IL-10 values in the blood has been revealed in patients with unstable angina and non-Q myocardial infarction (non-Q MI), and NTproBNP — for patients with Q-wave myocardial infarction (QMI). Development of complications of ACS patients was preceded by a higher IL-6 and IL-10 in their saliva, in comparison with the blood. Conclusion. The obtained results could be used as supplementary diagnostic criteria, which allow to predict any development of cardiovascular complications throughout the hospital stay period of ACS patients.

Key words: acute coronary syndrome, complications, С-reactive protein, natriuretic peptide, interleukin-6, interleukin-10.

 

References

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Physical rehabilitation for COPD

Leyla A. Ergeshova, Moscow, Russia

Abstract. Aim. To increase the effect of treatment in patients with COPD by developing and introduction a comprehensive physical rehabilitation therapy. A total of 14 patients fully underwent physical rehabilitation. For comparative evaluation of rehabilitation programs, we conducted surveillance of patients who received only pharmacological treatment (8). All patients undergone 6-minute walking test, PFT, ECG, St. George’s questionnaire. In physical rehabilitation group, dyspnea decreased in 8 patients. In the comparison group dyspnea decreased in only one patient. In all groups, PFT parameters and blood gas values remained at the same level approximately. Despite the fact that the parameters of PFT remained at the same level; in physical rehabilitation groups exercise tolerance increased in 12 people. In group 2, traveled distance decreased, indicating that the contribution of rehabilitation methods improve the condition in patients with COPD.

Key words: physical rehabilitation, COPD.

 

References

1. Belevskii, A.S. Reabilitaciya bol'nyh s patologiei legkih / A.S. Belevskii// Atmosfera. Pul'monologiya i allergologiya. — 2007. — № 4. — S.14—17.
2. Leschenko, I.V. Osnovnye polozheniya mezhdunarodnyh klinicheskih rekomendacii po diagnostike i lecheniyu hronicheskoi obstruktivnoi bolezni legkih / I.V. Leschenko, N.A. Esaulova // Pul'monologiya. — 2005. — № 3. — S.101—111.
3. Ob'edinennoe soglashenie po legochnoi reabilitacii: rekomendacii ATS i EPS // Pul'monologiya. — 2007. — № 7. — S.15—16.
4. Pul'monologiya: nacional'noe rukovodstvo / pod red. A.G. Chuchalina. — M.: GEOTAR-Medicina, 2007. — S.644—647.
5. Sinopal'nikov, A.I. Epidemiologiya HOBL: sovremennoe sostoyanie aktual'noi problemy / A.I. Sinopal'nikov, A.V. Vorob'ev // Pul'monologiya. — 2007. — № 6. — S.78—86.
6. Skeletal muscle dysfunction in chronic obstructive pulmonary disease: astatement of the American Thoracic Society and European Respiratory Society / American Thoracic Society, European Respiratory Society // Am. J. Respir. Crit. Care Med. — 1998. — Vol. 158 — P.629—634.
7. Global Initiative for chronic obstructive lung disease // WHO. — 2011. — P.41—43.

 

The frequency of dyslipidemia in HIV-patients and its correlation with markers of microbial translocation and inflammation

Gulshat R. Khasanova, PhD, Associated professor of the Department of Pediatric Infectious Diseases of SBEI HPE «Kazan State Medical University» of Russian Ministery of Health, Kazan, Infectious Diseases Specialist of the Center of AIDS and Infectious Diseases of Ministery of Health of Tatarstan Republic, Kazan, Russia, tel. 8-843-267-80-06, e-mail: gulshatra@mail.ru

Abstract. The lipid profile in association with markers of microbial translocation and inflammation in HIV-patients was investigated. Decreased level of high-density-lipoproteins was observed in 51,6%, increased levels of low-densitylipoproteins — in 35%, triglycerides — in 22,3%, total cholesterol — in 23% of patients. Negative correlation of sCD14 with high-density-lipoproteins and positive correlation with level of triglycerides was noted. Prevalence rates of abnormal levels of high-density-lipoproteins and triglycerides was 1,74 and 9,11, respectively, in group with high (>2,94 μg/ml) levels of sCD14 versus group with low level of sCD14. Level of high-density-lipoproteins was negatively correlated with ferritin concentration (r=–0,32; p=0,00024) and TNF-α (r=–0,63; p=0,000001). Positive correlation of triglycerides with IL-1β was found (r=0,34; p=0,0037). Conclusion: Dyslipidemia in HIV-patients is associated with microbial translocation and inflammation.

Key words: HIV-infection, dyslipidemia, endotoxin, microbial translocation, inflammation.

 

References

1. Antiretroviral Therapy Cohort Collaboration. Cuses of death in HIV-1-infected patients treated with antiretroviral therapy, 1996—2006; collaborative analysis of 13 HIV cohort studies // Clin. Infect. Dis. — 2010. — Vol. 50. — P.1387—1396.
2. Cardiovascular disease risk factors in HIV patients — association with antiretroviral therapy: results from the DAD study / N. Friis-Moller, R. Weber, P. Reiss [et al.] // AIDS. — 2003. — Vol. 17(8). — P.1179—1193.
3. The macrophage: the intersection between HIV infection and atherosclerosis / S.M. Crowe, C.L. Westhorpe, N. Mukhamedova [et al.] // J. Leukoc. Biol. — 2010. — Vol. 87. — P. 589—598.
4. Microbial translocation is a cause of systemic immune activation in chronic HIV / J.M. Brenchley, D.A. Price, T.W. Schacker [et al.] // Nat. Med. — 2006. — Vol. 12. — P.1365—1371.
5. Bacterial endotoxin activity in human serum is associated with dyslipidemia, insulin resistance, obesity, and chronic inflammation / M.I. Lassenius, K.H. Pietilainen, K. Kaartinen [et al.] // Diabetes Care. — 2011. — Vol. 34. — P.1809—1815.
6. Endotoxemia, immune response to periodontal pathogens, and systemic inflammation associate with incident cardiovascular disease events / P.J. Pussinen, K. Tuomisto, P. Jousilahti [et al.] // Arterioscler. Thromb. Vasc. Biol. — 2007. — Vol. 27. — 1433—1439.
7. Hasanova, G.R. Mikrobnaya translokaciya i sistemnyi vospalitel'nyi otvet pri VICH-infekcii [Microbial translocation and systemic inflammatory response in HIV-infection] / G.R. Hasanova, O.I. Bikkinina, V.A. Anohin // Saratovskii nauchno-medicinskii zhurnal [Saratov scientific-medical journal]. — 2013. — № 5. — S.508—512.
8. Diagnostika i korrekciya narushenii lipidnogo obmena s cel'yu profilaktiki i lecheniya ateroskleroza. Rossiiskie rekomendacii, IV peresmotr [Diagnosis and correction of dyslipidemia for prevention and treatment of atherosclerosis. Russian recommendations. 4-th edition, Moscow, 2009]. — M., 2009. — URL: http://athero.ru/Lipids-rus-2009.pdf 

 

REVIEWS

Practice of antibacterial treatment for community-acquired pneumonia. From the literature review to own data

Galina V. Lysenko, post-graduate student of phthisiopulmonology chair SBEI HPE «Kazan State Medical University» of the Ministry of Health of Russia, Kazan, Russia, tel. 8-843-231-79-73, e-mail: galina.lysenko@tatar.ru

Abstract. Aim. To compare domestic and foreign studies of frequency of use of antibacterial drugs with the data obtained in the Republic of Tatarstan, the last 15 years. Material and methods. A review of domestic and foreign publications devoted to implementation community-acquired pneumonia (CAP) guidelines in the last 15 years was performed. Retrospective analysis of 1695 cases of pneumonia treated in Tatarstan hospitals in 2009—2011 was made. Results. Dynamics of changes in prescribing antibiotics for CAP in the last 15 years has the general trends in Russia and abroad. Among them, reduction of aminoglycosides, first generation cephalosporins, sulfonamides, the prevalence of III generation cephalosporins, macrolides and respiratory fluoroquinolones revealed. At the same time, the survey revealed wide use the second generation fluoroquinolones, particularly ciprofloxacin. Transnational studies show that consumption of antibiotics is different in different countries of Europe, and frequency of antibiotic prescription and antibiotic resistance has a direct correlation. In 2011 in Tatarstan most frequently prescribed antibiotics were III generation cephalosporins (81,6%), macrolides (39,9%) and aminopenicillins (17,3%). Conclusion. Analysis of domestic and foreign literature and a comparison with own data showes that the worldwide prescribing pattern of antimicrobials has the general trends. In recent decades, clinical guidelines have been revised and best choice for CAP was the combination therapy of antipseudomonal beta-lactam with modern macrolide or respiratory fluoroquinolone (III—IV generation). Data obtained in Tatarstan, demonstrate a relatively high rate of following this choice at the turn of the first and second decades of the XXI century.

Key words: community-acquired pneumonia, antibiotics, the frequency of application, inpatients.

 

References

1. Sinopal'nikov, A.I. Novye rekomendacii po vedeniyu vzroslyh pacientov s vnebol'nichnoi pnevmoniei: diagnostika, ocenka stepeni tyazhesti, antibakterial'naya terapiya, profilaktika / A.I.Sinopal'nikov, L.S.Strachunskii, O.V.Sivaya // Klinicheskaya mikrobiologiya i antimikrobnaya himioterapiya. —2001. —T.3, № 4. — S.355—375.
2. Sinopal'nikov, A.I. Vnebol'nichnaya pnevmoniya u vzroslyh: podhody k antibakterial'noi terapii s pozicii sovremennyh klinicheskihrekomendacii//Terapevticheskiiarhiv.—2010.— T. 82, № 8. — S.5—10.
3. Chuchalin, A.G. Vnebol'nichnaya pnevmoniya u vzroslyh: prakticheskie rekomendacii po diagnostike, lecheniyu i profilaktike: posobie dlya vrachei / A.G. Chuchalin, A.I. Sinopal'nikov, R.S. Kozlov [i dr.]. — M., 2010. — 106 s.
4. Vizel', A.A. Pnevmoniya kak nereshennaya problema XXIveka / A.A. Vizel'// Healthy Nation. — 2011. — № 3(6). — S.22—23.
5. Gil'manov, A.A. Vliyanie vnedreniya protokolov diagnostiki i lecheniya na kachestvo okazaniya stacionarnoi pomoschi bol'nym vnebol'nichnoi pnevmoniei / A.A. Gil'manov, A.A. Vizel', R.F. Batyrshin [i dr.] // Problemy standartizacii v zdravoohranenii. — 2002. — № 2. — S.59.
6. Hamitov, R.F. Ftorhinolony v lechenii pacientov, gospitalizirovannyhsvnebol'nichnoipnevmoniei/R.F.Hamitov, R.B. Nikitina // Kazanskii medicinskii zhurnal. — 2011. — T. XCII, № 1. — S.1—4.
7. Kozlov, R.S. Farmakoepidemiologicheskii analiz lecheniya vnebol'nichnoi pnevmonii v ambulatornyh usloviyah / R.S. Kozlov, S.A. Rachina, N.P. Domnikova [i dr.] // Klinicheskaya mikrobiologicheskaya antimikrobnaya himioterapiya. — 2000. — T. 2, № 3. — S.74—81.
8. Korsun, L.V. Retrospektivnoe issledovanie lekarstvennoi terapii vnebol'nichnoi pnevmonii u bol'nyh pozhilogo vozrasta s soputstvuyuschei patologiei IBS i HOBL / L.V. Korsun, N.D. Bunyatyan, D.B. Uteshev // Zdorov'e i obrazovanie v XXI veke. — 2009. — T. 11, № 1. — S.40—41.
9. Leschenko, I.V. Vnebol'nichnaya pnevmoniya: faktory riska  neblagopriyatnogo ishoda i rezul'taty vnedreniya territorial'nogo standarta v Sverdlovskoi oblasti /I.V.Leschenko,N.M.Trifanova // Doktor Ru. — 2010. —T. 57, № 6. — S.57—63.
10. Nazarenko, G.I. Antibakterial'naya terapiya vnebol'nichnyh pnevmonii (analiz literatury i sobstvennyh dannyh, klinicheskaya effektivnost' rekomendacii) / G.I. Nazarenko, A.N. Antipin, Yu.K. Novikov // Pul'monologiya. — 2004. — № 4. — S.60—66.
11. ESAC Project Group. European Surveillance of Antimicrobial Consumption (ESAC): quality indicators for outpatient antibiotic use in Europe / S.Coenen, M.Ferech, F.M.Haaijer-Ruskamp[etal.]//Qual.Saf.HealthCare.—2007.—Vol.16, № 6. — P.440—445.
12. Socioeconomic determinants of outpatient antibiotic use in Europe / G. Masiero, M. Filippini, M. Ferech, H. Goossens // Int. J. Public. Health. — 2010. — Vol. 55, № 5. —P.469—478.
13. ESAC Project Group. European Surveillance of Antimicrobial Consumption (ESAC): systemic antiviral use in Europe / N.Adriaenssens,S.Coenen,A.C.Kroes[etal.]//J.Antimicrob. Chemother. — 2011. — Vol. 66, № 8. — P.1897—1905.
14. Exposure to antibacterial agents with QT liability in 14 European countries: trends over an 8-year period / E.Raschi, E.Poluzzi, C. Zuliani [et al.] // Br. J. Clin. Pharmacol. — 2009. — Vol. 67, № 1. — P.88—98.
15. European Survaillance of Antibiotic Comsuption (ESAC) Project Group. Hospital consumption of antibiotics in 15 European countries: results of the ESAC Retrospective Data Collection (1997—2002) / R.H. Vander Stichele, M.M. Elseviers, M. Ferech [et al.] // J. Antimicrob. Chemother. — 2006. — Vol. 58, № 1. — P.159—167.
16. ESAC Project Group. Outpatient antibiotic use in Europe and association with resistance: across-national data base study / H. Goossens, M. Ferech, R. Vander Stichele, M. Elseviers // Lancet. — 2005. — Vol. 365, № 9459. — P.579—587.
17. Hospital antibiotic consumption in Switzerland: comparison of a multicultural country with Europe / C. Plüss-Suard, A. Pannatier, A. Kronenberg [et al.] // J. Hosp. Infect. — 2011. — Vol. 79, № 2. — P.166—171.
18. Ten years of antibiotic consumption in ambulatory care: trends in prescribing practice and antibiotic resistance in Austria / S. Metz-Gercek, A. Maieron, R. Strauss [et al.] // BMC Infect. Dis. — 2009. — Vol. 9. — P.61.
19. Differences in antibiotic prescribing in three university hospitals in the Baltic region revealed by a simple protocol for quality assessment of therapeutic indications / U. Dumpis, J. Gulbinovic, J. Struwe [et al.] // Int. J. Clin. Pharmacol. Ther. — 2007. — Vol. 45, № 10. — P.568—576.
20.  A comparison of antibiotic point prevalence survey data from four Irish regional/general hospitals / C. Naughton, Y. Hennessy, C. Mannion, M. Philbin // Ir. J. Med. Sci. — 2011. — Vol. 180, № 2. — P.457—461.
21. Prescription of antibiotics for adults hospitalized with community-acquired pneumonia in Korea in 2004: a population-based descriptive study / Y.K. Yoon, E.J. Kim, B.C. Chun [et al.] // Respirology. — 2012. — Vol. 17, № 1. — P.172—179.
22. An audit of inpatient management of community-acquired pneumonia in Oman: a comparison with regional clinical guidelines / S.S. Al-Abri, S. Al-Maashani, Z.A. Memish, N.J. Beeching // J. Infect. Public. Health. — 2012. — Vol. 5, № 3. — P.250—256.
23. Factors effecting the duration of hospitalization and mortality in patients with community-acquired pneumonia / N. Pişkin, H. Aydemir, N. Oztoprak [et al.] // Mikrobiyol. Bul. — 2009. — Vol. 43, № 4. — P. 597—606.
24. Critical evaluation of antimicrobial use — a Turkish university hospital example / S. Hosoglu, Z. Parlak, M.F. Geyik, Y. Palanci // J. Infect. Dev. Ctries. — 2013. — Vol. 7, № 11. — P.873—879.
25. Antibiotic therapy for inpatients with community-acquired pneumonia in a developing country / H.T. Trinh, P.H. Hoang, M. Cardona-Morrell [et al.] // Pharmacoepidemiol. Drug Saf. — 2014. — Mar. 19. — Doi: 10.1002/pds.3614 [Epub ahead of print].
26. Adherence to ATS guidelines for hospitalized patients with community-acquired pneumonia /D.C.Malone,H.M.Shaban // Ann. Pharmacother. — 2001. — Vol. 35, № 10. — P.1180— 1185.
27. Antibiotic prescribing rates in the US ambulatory care setting forpatientsdiagnosedwithinfluenza,1997—2001/G.Ciesla, S. Leader, J. Stoddard // Respir. Med. — 2004. — Vol. 98, № 11. — P.1093—1101.
28. Patterns of initial antibiotic therapy for community-acquired pneumonia in U.S. hospitals, 2000 to 2009 / A. Berger, J. Edelsberg, G. Oster [et al.] // Am. J. Med. Sci. — 2014. — Vol. 347, № 5. — P.347—356.
29. On behalf of the Active Bacterial Core Surveillance (ABCs) Team. Outpatient antibiotic prescribing and nonsusceptible Streptococcus pneumonia in the United States, 1996—2003 / L.A. Hicks, Y.W. Chien, T.H.Jr. Taylor [et al.] // Clin. Infect. Dis. — 2011. — Vol. 53, № 7. — P.631—639.

 

DISCUSSION

Definition of the health concept within the bounds of quality of life study in dental patients

Nadezhda S. Fyodorova, Candidate of Medical Science, Associate Professor of the Department of Prosthetic Dentistry of the Medical Faculty in the Federal State Educational Establishment of Higher Professional Education «The Chuvash State University named after I.N. U lyanov», Cheboksary, Russia, tel. 8-905-341-17-49, e-mail: nadegdafedorova@gmail.com

Rinat A. Salev, Doctor of Medicine, Professor of the Department of Prosthetic Dentistry, Dean of the Dental Faculty of SBEI HPE «Kazan State Medical University» of the Ministry of Health of Russia, Kazan, Russia

Abstract. The aim of this research work was to briefly review the foreign literature devoted to the research of concepts of Disease, Oral Health and Quality of Life, and to reveal relationship and complementarities of these concepts. The characteristics of two existing models of Health: medical (biological) and socioenvironmental are given in the bounds of proposed review. We validate necessity for gradual moving from one model of assessing Health conception to the other. We listed some of Health and Disease concepts definitions proposed earlier. Definition examples of the Oral Health concept are made. Some kinds of dental diseases measurements and its consequences are described. A general definition of the Quality of Life concept and its different interpretations considering this concept in medicine, philosophy, ecology and sociology aspects are given.

Key words: dentistry, health, oral health, disease, quality of life.

 

References

1. Novik, A.A. Rukovodstvo po issledovaniyu kachestva zhizni v medicine [Guidelines of Quality of Life Research in Medicine] / A.A. Novik, T.I. Ionova. — M.: ZAO «OLMA Media Grupp», 2007. — C.18.
2. Raizberg, B.A. Sovremennyi ekonomicheskii slovar' [Modern Dictionary of Economics] / B.A. Raizberg, L.Sh. Lozovskii, E.B. Starodubceva. — M.: INFRA-M, 1999. — C.235—240.
3. Loker, D. Indikatory sub'ektivnoi ocenki sostoyaniya stomatologicheskogozdorov'ya/D.Loker//Analizrezul'tatov issledovaniya stomatologicheskogo zdorov'ya: ocenka sostoyaniyazdorov'yaikachestvazhizni:tez.konf. —Cheppel Hill, Severnaya Karolina, 1996. — S.12—23.
4. Patrick, D. Health Status and Health Policy: Quality of Life in Health Care Evaluation and Resource Allocation / D. Patrick, P. Erickson. — New York: Oxford University Press, 1993. — P.416—428.
5. Associations of self-reported oral health with physical and mental health in a nationally representative sample of HIV persons receiving medical care / I.D. Coulter, K.S. Heslin, M. Marcus [et al.] // Quality of Life Research. — 2002. — Vol. 11. — P.57—70.
6. Integrative Health Care Under Review: An Emerging Field / I.D. Coulter, К. Khorsan, C. Crawford [et al.] // Journal of Manipulative and Physiological Therapeutics. — 2010. — Vol. 33. — P.690—710.
7. Measuring oral health status: theoretical and methodological challenges/I.Coulter,M.Marcus,K.Atchison//SocialScience and Medicine. — 1994. — Vol. 38. — P.1531—1541.
8. Nettleton, S. The Sociology of Health and Illness / S. Nettleton. — Cambridge: Polity Press, 1995. — P.56—87.
9. Physician-patient communication about dietary supplements / D.M.Tarn,D.A.Paterniti,J.S.Good[etal.]//PatientEducation and Counseling. — 2013. — Vol. 91. — P.287—294.
10. Linking clinical variables with health-related quality of life: a conceptual model of patient outcomes / I. Wilson, P. Cleary // Journal of the American Medical Association. — 1995. — Vol. 273. — P.59—65.
11. 11. Yewe-Dwyer, M. The definition of oral health / M. Yewe-Dwyer // British Dental Journal. — 1993. — Vol. 174. — P. 224—225.
12. Dolan, T. Identification of appropriate outcomes for an aging population / T. Dolan // Special Care in Dentistry. — 1993. — Vol. 13. — P.35—39.
13. Albrecht, G. A sociological perspective on health-related qualityofliferesearch/G.Albrecht,R.Fitzpatrick//Advances in Medical Sociology. — 1994. — Vol. 5. — P.1—21.
14. Abeles, R. Aging and Quality of Life / R. Abeles, H. Gift, M. Ory. — New York: Springer Publishing Company, 1994. — P.25—37.
15. Raphael, D. Qualityoflifetheoryandassessment:whatarethe implications for health promotion. Issues in Health Promotion Series / D. Raphael, I. Brown, R. Renwick, I. Rootman. — University of Toronto, Centre for Health Promotion, 1994. — P.17—23.

 

HELP FOR PRACTITIONER

Diagnosis and treatment of sarcoidosis. Summary of Federal Conciliative Clinical Recommendations. Part I. Classification, etiopathogenesis, clinic

Alexander G. Chuchalin, Professor, MD, Director FGBI «Institute of Pulmonology» FMBA of Russia, Chairman of the Russian Respiratory Society, Chief Specialist supernumerary therapist pulmonologist the Ministry of Health, Academician, e-mail: chuchalin@inbox.ru

Alexander A. Vizel, Professor, MD, Head of the Department of Phthisiopulmonology of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, Chief supernumerary specialist pulmonologist Ministry of Health of Tatarstan, e-mail: lordara@inbox.ru

Mikhail M. IlkovIch, Professor, MD, Head of the Department of Pulmonology FPO with clinic Medical University PSPbGMU them. IP Pavlova Russian Ministry of Health, Chief supernumerary specialist pulmonologist St. Petersburg, e-mail: mih.ilkovich@yandex.ru

Sergey N. Avdev, Professor, MD, Deputy Director for Science FGBI «Institute of Pulmonology» FMBA of Russia, e-mail: serg_avdeev@list.ru

Nail B. Amirov, Ph. D., Professor of General Practice Medical University «Kazan State Medical University» of Ministry of Health of Russia, professor, Academician of RAE, e-mail: namirov@mail.ru

Olga P. Baranova, MD, senior researcher IL D Institute of Pulmonology, Medical University PSPbGMU them. acad. Pavlov of Russian Ministry of Health, e-mail: dr_baranova@mail.ru

Sergey E. Borisov, Professor, MD, Deputy Director for Research and clinical work of the Moscow City Scientific and Practical Center for Tuberculosis Department of Health in Moscow, e-mail: sebarsik@gmail.com

Irina Yu. Vizel, MD, assistant lecturer therapy and family medicine GBOU DPO «Kazan State Medical Academy» Russian Ministry of Health, e-mail: tatpulmo@mail.ru

Olga V. Lovacheva, MD, Head endoscopy department FGBI «Central Research Institute of Tuberculosis», RAMS, Professor of phthisiology SBEI DPO «Russian Medical Academy», e-mail: lovol@zmail.ru

Nikolay V. Ovsyanikov, Ph. D., Head of Pulmonology BUZ Omsk region «City Clinical Hospital № 1. Kabanov», e-mail: niklajjovs@rambler.ru

Dmitry V. Petrov, pulmonologist pulmonology clinic cabinet BUZ Omsk region «City Clinical Hospital № 1. Kabanov», e-mail: dmitrpetrov@bk.ru

Vladimir V. Romanov, Professor, MD, Leading researcher of the differential diagnosis of pulmonary tuberculosis and extracorporeal therapies FGBI CTRI RAMS, MD, e-mail: romanov@internets.ru

Maria V. Samsonovа, MD, Head of the Laboratory of Pathological Anatomy and Immunology FGBI «Institute
of Pulmonology» FMBA Russia, e-mail: samary@mail.ru

Irina P. Solovyova, MD, Head of the Laboratory of Pathological Anatomy of the First Moscow State Medical University of Sechenov, Professor, e-mail: ripporg@mail.ru

Igor E.Stepanian, Professor, MD, Leading researcher of the differential diagnosis of pulmonary tuberculosis and extracorporeal therapies FGBI CTRI RAMS, MD, e-mail: drstepanyan@mail.ru

Igor E. Tyurin, Professor, MD, Head of the department of radiation diagnosis, radiotherapy and medical physics GBOU DPOR MAPO, Chief Specialist in diagnostic imaging Ministry of Public Health, e-mail: igortyurin@gmail.com

Andrey L. Cherniayev, Professor, MD, Head of the Department of Pathology FGBI «Institute of Pulmonology» FMBA of Russia, e-mail: cheral12@gmail.com

Evgeny I. Shmelev, Professor, MD, Head of the differential diagnosis of pulmonary tuberculosis and extracorporeal therapies FGBI CTRI RAMS, e-mail: eishmelev@mail.ru

Natalia M. Shmeleva, Ph. D., pulmonologist District Northern Administrative District of Moscow, e-mail: eishmelev@mail.ru

Abstract. An abridged adaptation of the Russian federal clinical guidelines for the diagnosis and treatment of sarcoidosis is presented. Material prepared by experts and includes all evidence up to date, the world's achievements in the study of this disease and a huge own clinical experience of the authors. In the first part the etiology, pathogenesis, epidemiology, clinical manifestations of sarcoidosis with various organs and systems involvement is revealed. The second part shows the path of the diagnostic and differential diagnostic search, determining management of patients with sarcoidosis, drug therapy options, prevention, and prognosis. Studying these recommendations allows doctors of all specialties to be qualified to conduct diagnostic search and adequate therapy of the disease, and to identify further management tactics. These guideline is intended for a wide range of practitioners and researchers.

Key words: sarcoidosis, diagnosis, treatment.

 

References

1. Borisov, S.E. Diagnostika i lechenie sarkoidoza organov dyhaniya / S.E. Borisov, I.P. Solov'eva, V.P. Evfim'evskii [i dr.]. — M.: NIIFP MMA, 2006. — 55 s.
2. Vizel', I.Yu. Sostoyanie bol'nyh sarkoidozom v ishodno i 10 let spustya pri razlichnoi taktike ih vedeniya (mul'ticentrovoi analiz) / I.Yu. Vizel', E.I. Shmelev, O.P. Baranova [i dr.] // Pul'monologiya. — 2012. — № 4. — 29—33.
3. Daurov, B.I. Sarkoidoz / B.I. Daurov. — M.: Overlei, 2006. — 264 s.
4. Disseminirovannye zabolevaniya legkih / pod red. prof. M.M. Il'kovicha. — M.: GEOTAR-Mediya, 2011. — 480 s.
5. Il'kovich, M.M. Sarkoidoz organov dyhaniya / M.M. Il'kovich, L.N. Novikova, V.S. Luchkevich. — SPb., 1996. — 66 s.
6. Intersticial'nye bolezni legkih / pod red. N.A. Muhina. — M.: Littera, 2007. — 432 s.
7. Intersticial'nye zabolevaniya legkih: rukovodstvo dlya vrachei / Pod red. M.M.Il'kovicha, A.N.Kokosova. — SPb.: Nordmedizdat, 2005. — 560 s.
8. Porazhenie serdechno-sosudistoi sistemy pri sarkoidoze / A.A. Vizel', N.B. Amirov, F.A. Mingaleev, R.N. Amirova // Vestnik mezhregional'nogo kliniko-diagnosticheskogo centra. — 2004. — T. III, vyp. 1. — S.129—134.
9. Potanin, A.V. Invazivnaya diagnostika pri sindromah vnutrigrudnoi limfadenopatii i disseminacii / A.V. Potanin, I.Yu. Vizel', V.P. Potanin, A.A. Vizel' // Vestnik sovremennoi klinicheskoi mediciny. — 2011. — T. 4, vyp. 3. — S.56—60.
10. Pul'monologiya: klinicheskie rekomendacii / pod red. A.G. Chuchalina. — M.: GEОTAR-Media, 2009. — 336 s.
11. Pul'monologiya. Nacional'noe rukovodstvo. Kratkoe izdanie / pod red. A.G. Chuchalina. — M.: GEОTAR-Media, 2013. — 800 s.
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Behavioral regulation level of tobacco smokers

Olga A. Sukhovskaya, PhD, Head of Advisory Telephone center for smoking cessation Sankt-Petersburg Research Institute of Phthisiopulmonology at Ministry of Health of Russia, Sankt-Petersburg, Russia, tel. 8-905-219-98-06, e-mail: sukhovskaia@mail.ru

Svetlana S. Ivanova, psychologist of Advisory Telephone center for smoking cessation Sankt-Petersburg Research Institute of Phthisiopulmonology at Ministry of Health of Russia, Sankt-Petersburg, Russia, tel. 8-911-845-72-52, e-mail: ktc01@mail.ru

Maria A. Smirnova, physician-therapist of Advisory Telephone center for smoking cessation Sankt-Petersburg Research Institute of Phthisiopulmonology at Ministry of Health of Russia, Sankt-Petersburg, Russia, tel. 8-903-093-89-89, e-mail: ktcniif_smirnova@mail.ru

Abstract. Aim. The purpose is to study behavioral regulation level of smokers. Methods. Under our observation were
328 smokers and 80 nonsmokers 20—70 aged. Determined: number of cigarettes per day, duration of smoking, the degree of nicotine dependence (ND) by the Fagerstrom test, Horn questionnaire for smoking motivation (MS), «Adaptability» questionnaire, which include behavioral regulation (BR), communicative potential (CP), moral norms (MN) and the total range of personal adaptive capacity (PAC). Results. The study showed that smokers had low level of BR (p <0,05) more frequently and had high levels of BR in 3,6 times less in the compared with nonsmokers. Smokers having low level of BR had higher (compared to the group with medium and high values of BR) scales values of MS, especially scales «Support for nervous tension», «Tobacco addiction». BR worsened with increasing number of cigarettes per day (r=0,57, p<0,05) and the lowest level of BR was observed in individuals who started regularly smoking before the age of 11 years. Conclusion. Smokers had significantly more frequently low level of behavioral regulation, especially for case with early start of regular smoking. Smokers with low levels of behavioral regulation had higher values of smoking motivation scales. The presence of a high degree of any factor of smoking motivation was accompanied with low level of behavioral regulation.

Key words: smoking, behavioral regulation, smoking status.

 

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