Vol. 7 Issue 2 (2014)

Обложка журнала

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LEADING ARTICLE

By the 200th anniversary of Kazan State Medical University. A brief history and scientific schools today. N.B. Amirov, A.A. Wiesel, S.D. Mayanskaya

ORIGINAL ARTICLES

Assessment of occupational risk of violations for health of medical workers by results of periodic medical examination. N.Kh. Amirov, Z.M. Berkheeva, R.V. Garipova

Asthma control problems in oupatient hospitals Samara region. A.V. Zhestkov, D.A. Nagatkin

Sensitivity estimates suboptimal health status using a questionnaire SHSQ-25. V.I. Kupaev, E.Yu. Marutina, O.Yu.Borisov

The level of hormones of hypophysis and sexual glands of teenagers with chronic hypertrophic gingivitis. E.V. Mamayeva, D.A. Tsinekker

Research of the dynamic occlusion of the pationts with periodontal disease. R.F. Mustakimova,G.T. Saleeva

Clinical and radiological evaluation of jaw bone augmentation according to the CONE-BEAM CT. G.T. Saleeva, Z.I. Yarulina, Yu.G. Sedov, P.N. Mikhalev

Influence of Trimetazidine МR (Tridukard) on chronic ischemic heart disease. N.B. Amirov, N.A. Tsibulkin, A.A. Morozova, E.B. Frolova, G.A. Muhamet-shina, O.J. Mihoparova, O.B. Oschepkova

Comparison of the effectiveness of articaine local anaesthesia for pulpotomy mandibular primary molars. T.Yu. Shiryak, R.A. Saleev, M.G. Gilyaziev, D.M. Mustaeva

The improved method of determining bile acids in serum by gas-liquid chromatography. Z.Sh. Minnullina

Primary sensitivity to antibacterials among Helicobacter pylori isolates from patients with chronic gastritisis and gastroduodenitis A.O. Pozdeeva, L.G. Morozova, O.K. Pozdeev, A.O. Pozdnyak

HELP FOR PRACTITIONER

Psychiatrist and expert in narcology. The legislationduring realization of preliminary and periodic medical examinations. S.V. Kuzmina

Preliminary clinical and laboratory stages of mana-gement of bruxism. G.T. Saleeva, I.I. Sagitov, L.R. Saleeva, D.B. Valieva

Application of soft chewing test at the electromyography of chewing muscles. M.A. Belousova, A.D. Goncharenko, S.N. Ermolev, N.K. Loginova

Mycobacterium tuberculosis drug resistance forming during the course of TB treatment. Realities of domestic TB management program and medical aspects of drug resistant TB epidemic prevention (part 2). A.L. Khanin, S.A. Dolgikh, I.B. Viktorova

CASE FROM PRACTICE

Clinical example of the effectiveness of antibacterial therapy with sarcoidosis skin. M.V. Listopadova, A.A. Punin, A.Yu. Kuzmenkov

EXPERIMENTAL MEDICINE TO APPLIED HEALTHCARE

Antihypoxic activity of 6-aryl-4-hydroxy-5,6-dihydro-4h-1,3-oxazines. S.S. Zykova

 

LEADING ARTICLE

PDF downloadBy the 200th anniVersary of kazan state medical uniVersity. A brief history and scientific schools today

Nail B. Amirov, MD, professor of the Department of General Practice of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, tel. (843) 291-26-76, e-mail: namirov@mail.ru

Alexander A. Vizel, MD, professor, Head of the Department of Phthisiopneumology of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, tel. (843) 296-25-99, e-mail: lordara@inbox.ru

Svetlana D. Mayansky, MD, professor of the Department of hospital therapy with a course of Endocrinology of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, e-mail: smayanskaya@mail.ru

Abstract. The article gives a brief historical background on the bright work of one of the leading medical universities in Russia — Kazan State Medical University. Kazan State Medical University (KSMU) in 2014 celebrates its bicentennial. KSMU began its history as a faculty of Kazan Imperial University in 1814, he is one of three medical schools, who are the founders of medical education in Russia. During its formation, Kazan State Medical University trained a galaxy of doctors who have made a significant contribution to world medicine, outstanding scientists whose names are known worldwide. And nowadays KSMU continues to stay in the top three leading medical universities in Russia on science activities. KSMU today has a staff of 140 doctors and 303 — candidate of medical sciences. As part of work KSMU 98 professors and 127 associate professors departments. Among them, 1 Academician, 1 Academy of Medical Sciences, 1 corresponding member of RAMS, academician RT 3 and 4 corresponding member of the Academy of Sciences of Tatarstan.

Key words: history KSMU, scientific activity.

 

References

  1. Abramova, T.E. K istorii razvitija pediatrii v Kazani / T.E. Abramova // Kazan. med. zhurnal. — 1964. — № 5. — S.133—136.
  2. Al’bickij, V.Ju. K istorii primenenija perkussii i auskul’tacii v klinikah Kazanskogo universiteta / V.Ju. Al’bickij // Klinicheskaja medicina. — 1976. — № 3. — S.144—145.
  3. Al’bickij, V.Ju. Kazanskij gosudarstvennyj medicinskij universitet: jetapy dvuhvekovogo puti, itogi i zadachi izuchenija istorii: aktovaja rech’ (15 maja 2006 g.) / V.Ju. Al’bickij. — Kazan’, 2006. — 34 s.
  4. Al’bickij, V.Ju. Rol’ kazanskih uchenyh v razvitii otechestvennoj gigieny / V.Ju. Al’bickij, A.B. Galljamov, M.M. Gimadeev // Kazan. med. zhurnal. — 1994. — № 3. — S.161—166.
  5. Amirov, N.H. Pediatricheskomu fakul’tetu KGMU — 70 let / N.H. Amirov, V.Ju. Al’bickij, I.V. Kljushkin // Kazan. med. zhurnal. — 2003. — № 1. — S.67—69.
  6. Guryleva, M.Je. K istorii prepodavanija ftiziatrii v Kazanskom medicinskom universitete / M.Je. Guryleva, A.A. Vizel’, F.T. Krasnopуorov // Problemy tuberkuleza. — 2001. — № 5. — S.60—62.
  7. D’jakonova, I.N. Istorija razvitija nauchnoj nevropatologii i psihiatrii v Kazani / I.N. D’jakonova, Ja.Ju. Popeljanskij, V.S. Chudnovskij. — Kazan’: Tatar. kn. izd-vo, 1974. — 56 s.
  8. Zhuchkova, N.I. Kazanskoe obshhestvo vrachej i obshhest-vennaja medicina v Rossii / N.I. Zhuchkova // Materialy jubilejnoj konferencii KGMI. — Kazan’, 1964. — T. XIV. — S.7—28.
  9. Zhuchkova, N.I. Pervye zubovrachebnye shkoly v Kazani (1899—1918) (k istorii zubovrachebnogo obrazovanija v Rossii) / N.I. Zhuchkova // Stomatologija. — 1996. — № 6. — S.67—69.
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  11. Istorija Kazanskogo gosudarstvennogo medicinskogo universiteta / V.Ju. Al’bickij, N.H. Amirov, A.S. Sozinov, A.B. Galljamov. — Kazan’: Magarif, 2006. — 374 s.: il.
  12. Kazanskij gosudarstvennyj medicinskij universitet (1804—2004 gg.): zavedujushhie kafedrami i professora: biograficheskij slovar’ / V.Ju. Al’bickij, M.Je. Guryleva, N.H. Amirov [i dr.]; pod red. V.Ju. Al’bickogo, N.H. Amirova. — Kazan’: Magarif, 2004. — 47 s.: il.
  13. Mendelevich, D.M. Zasedanie kafedry. Sub’ektivnye zametki na poljah istorii kazanskoj psihiatrii / D.M. Mendelevich. — Kazan’: Shkola, 2004. — 258 s.
  14. Muhamed’jarov, F.G. Kazanskij gosudarstvennyj medicinskij institut za 130 let / F.G. Muhamed’jarov // Tr. Kazan. gos. med. in-ta. — Kazan’, 1946. — Vyp. 2. — S.54—58.
  15. Muhamed’jarov, F.G. Kazanskij gosudarstvennyj medicinskij institut k 30-letiju godovshhiny Tatarskoj ASSR / F.G. Muhamed’jarov // Tr. sanitarno-gigienicheskogo fakul’teta. — Kazan’: Tatgosizdat, 1951. — T. 1.
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  17. Vestnik sovremennoj klinicheskoj mediciny. — 2014. — T. 7, vyp. 1. — S.65—77.

 

ORIGINAL ARTICLES

PDF downloadAssessment of occupational risk of violations for health of medical workers by results of periodic medical examination

Nail Kh. Amirov, MD, professor of the Department of Hygiene and occupational health of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, Kazan, Russia, е-mail: amirovn@yandex.ru

Zukhra M. Berkheeva, MD, professor of the Department of Hygiene and occupational health of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, Kazan, Russia, tel. 8-905-310-74-46, е-mail: kgmu_profpat@mail.ru

Railya V. Garipova, PhD, assistant of the Department of Hygiene and occupational health of SBEI HPE «Kazan State medical university» of russian ministry of Health, Kazan, russia, tel. 8-917-255-38-44, е-mail: railyagaripova@mail.ru

Abstract. The methodology of occupational risk assessment for workers’ health was applied to analysis of medical examination data. Aim. Occupational risk assessment for health care workers. Material and methods. Periodical medical examinations conducted 942 health care workers Age and length of service distributions were similar for all groups [mean age (43,2±0,4) years, mean length of service (15,1±0,3) years].The analysis and grouping of diseases were performed according to ICD-10 (WHO, 1995). The data were processed statistically with calculation of odds ratio, relative risk, and etiological fraction. Results. The elevated relative risk of morbidity was revealed for deforming dorsopathies, diseases of female sexual system and digestive organs.

Key words: health care workers, health, оccupational risk.

 

References

  1. Rukovodstvo po gigienicheskoi ocenke faktorov rabochei sredy i trudovogo processa. Kriterii i klassifikaciya uslovii truda. Rukovodstvo R.2.2.2006-05.
  2. Metodicheskie rekomendacii po ocenke professional’nogo riska po dannym periodicheskih medicinskih osmotrov. — M., 2006. — 24 s.
  3. Denisov, E.I. Professional’no obuslovlennaya zabolevaemost’ i ee dokazatel’nost’ / E.I. Denisov, P.V. Chesalin // Medicina truda i promyshlennaya ekologiya. — 2007. — № 10. — S.1—9.
  4. Rukovodstvo po ocenke professional’nogo riska dlya zdorov’ya rabotnikov. Organizacionno-metodicheskie osnovy, principy i kriterii ocenki. Rukovodstvo R.2.2.1766-03.

 

PDF downloadAsthma control problems in oupatient hospitals samara region

Alexander V. Zhestkov, MD, professor, the head of the chair of clinical microbiology, immunology and allergology of the Samara State Medical University, tel. 260-33-61, e-mail: zhestkovav@yandex.ru

Dmitry A. Nagatkin, the correspondence PhD student of the chair of clinical Microbiology, Immunology and Allergology of the Samara State Medical University, tel. 8-927-689-85-78, e-mail: dmitrynagatkin@gmail.com

Abstract. The purpose of the study — to analyze the level of control the symptoms of bronchial asthma outpatient in the Samara region. Object and methods. The study involved 156 people , average age was (40,66±10,60) years, of which 55,13% of the women (n=86) and 44,87% of men (n=70). Results and discussion. Proved that the lack of use of questionnaires to control asthma symptoms contributes to poor disease control and leads to an overestimation of control. Also proven correlation between the questionnaires ACQ-5 and ACT and revealed the relationship between poor control of the disease and body mass index and the index of a smoker. Conclusion. Insufficient use of questionnaires to control the symptoms of asthma among physicians and narrow specialists leads to a reassessment of control and inadequate management of patients with mild to moderate asthma.

Key words: asthma, asthma management, ACQ-5, ACT.

 

References

  1. Fedoseev, G.B. Sovremennye predstavlenija o prichinah vozniknovenija, osobennostjah techenija i lechenija bronhial’- noj astmy: aktovaja rech’ / G.B. Fedoseev; 1-j Leningradskij med. in-t im. akademika I.P. Pavlova. — L., 1982. — 28 s.
  2. Chikina, S.Ju. Novyj vzgljad na fenotipy bronhial’noj astmy/ S.Ju.Chikina // Pul’monologija i allergologija. — 2012. — № 2. — S.2—6.
  3. Is asthma a sorted out disease? Results of a European survey / R. Walters, К. Annunziata, G. Castillo // EAACI Congress. — 2009. — Abstract 167. — P.78—79.
  4. Severe asthma: from characteristics to phenotypes to endotypes/ S. Wenzel //Clin. Exp. Allergy. — 2012. — Vol.42, №5. — P.650-658.
  5. The cost of persistent asthma in Europe: an international population-based study in adults / S. Accordini, A.G. Corsico, M. Braggion [et al.] // Int. Arch. Allergy Immunol. — 2013. — Vol. 160. — P.93—101.
  6. The global burden of asthma: executive summary of the GINA Dissemination Committee report / M. Masoli, D. Fabian, S. Holt [et al.] // Allergy. — 2004. — Vol. 59, № 5. — P.469—678.
  7. Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organi- zation Consultation on Severe Asthma / J. Bousquet, E. Mantzouranis, A.A. Cruz [et al.] // J. Allergy Clin. Immunol. — 2010. — Vol. 126. — P.926—938.

 

PDF downloadSensitivity estimates suboptimal health status using a questionnaire SHSQ-25

Vitalii I. Kupaev, MD, professor, Head of the Department of General practice of the Samara State medical university of Russian Ministry of Health, e-mail: vk1964sam@rambler.ru

Ekaterina Yu. Marutina, graduate student of the Department of General Practice of the Samara State Medical University of Russian Ministry of Health, e-mail: Ekaterina_m_u@mail.ru

Oleg Yu.Borisov, graduate student of the Department of General Practice of the Samara State Medical University of Russian Ministry of Health, e-mail: lekar1977@yandex.ru

Abstract. The problem of prevention of cardiovascular disease continues to be relevant. Integration of new questionnaires and instrumental techniques in the screening assay system represents to be promising for evaluating the health of the patient. Aim. Establish the relationship between the level of suboptimal health status as measured by the questionnaire SHSQ-25, and risk factors for cardiac disease. Material and methods. Viewed 459 residents of Samara, who had no history of disease and did not receive treatment in the last two weeks. Used a screening questionnaire diagnosis of suboptimal health status SHSQ-25, risk factors for cardiovascular disease, determining indicator of endothelial function (IEF) by computer photopletismography. Results. SHSQ-25 questionnaire showed significant differences between the two groups of factors and without risk factors for cardiovascular disease at 3 scales, fatigue, cardiovascular system, immune system (p<0,05). We compared level index smoker, age BMI, SBP, DBP and IEF between the higher and lower SHS score. Group was defined as the media of the total SHS score (higher SHS score ≥ 14, lower SHS score < 14). IEF showed significant differences between the two groups. Linear regression also showed association between SHS and IEF. Conclusion. Application questionnaire SHSQ-25 and instrumental diagnostics PPE allow us to estimate the risk of heart of vascular disease at the preclinical stage.

Key words: suboptimal health status, endothelial dysfunction, risk factors, cardiovascular disease.

 

References

  1. Shal'nova, S.A. Analiz smertnosti serdechno-sosu- distyh zabolevanii v 12 regionah Rossiskoi Federacii, uchastvuyuschih v issledovanii «Epidemiologiya serdechno-sosudistyh zabolevanii v razlichnyh regionah Rossii» / S.A. Shal'nova, A.O. Konradi, Yu.A. Karpov [i dr.] // Rossii- skii kardiologicheskii zhurnal. — 2012. — № 5 (97). — S.6—11.
  2. 2008—2013 Action plan for the global strategy for prevention and control of non communicable diseases. WHO, 2009.
  3. Yu-Xiang, Yan. Development and Evaluation of a Questionnaire for Measuring Suboptimal Health Status in Urban Chinese / Yan Yu-Xiang, Liu You-Qin, Li Man [et al.] //J. Epidemiol. — 2009. — Vol. 19(6). — P.333—341.
  4. Lebedev, P.A. Diagnostika funkcii sosudistogo endoteliya u bol'nyh s serdechno-sosudistymi zabolevaniyami / P.A. Lebedev, L.I. Kalakutskii, S.P. Vlasova. — Samara, 2004. — 18 s.
  5. Safar, M.E. Current perspectives on arterial stiffness and pulse pressure in hypertension and cardiovascular disease / M.E. Safar, B.I. Levy, H. Struijker-Bouder // Circulation. — 2003. — Vol. 107. — P.2864—2869.
  6. Yu-Xiang, Yan. Association of Suboptimal Health Status and Cardiovascular Risk Factors in Urban Chinese Workers / Yan Yu-Xiang, Dong Jing, Liu You-Qin [et al.] // Journal of Urban Health: Bulletin of the New York Academy of Medicine. — 2012. — Vol. 89, № 2. — P.329—338.

 

PDF downloadThe level of hormones of hypophysis and sexual glands of teenagers with chronic hypertrophic gingivitis

Elena V. Mamayeva, MD, senior lecturer at the chair of children’s stomatology of Kazan State medical university of the Ministry of Health of Russia, Kazan, Russia, tel. 8-917-851-27-45, e-mail: mamaeva49.49@mail.ru

Dina A. Tsinekker, PhD, assistant at the chair of children’s stomatology of Kazan State medical university of the Ministry of Health of Russia, Kazan, Russia, tel. 8-903-341-46-47, e-mail: dzinecker@hotmail.ru

Abstract: Research objective — estimating specific relationship of chronic hypertrophic gingivitis with the level of hormones of hypophysis and sexual glands of teenagers. There has been carried out a complex investigation of 104 schoolchildren of 13—15 years (56 boys, 48 girls) with the analyses for luteinizing and follicle-stimulating hormones, testosterone and estradiol. Results and discussion. For the teenagers of 13—15 years suffering from chronic hypertrophic gingivitis the level of hormones of hypophysis is within the bottom border of physiological norm which strengthens hypertrophy semiology in the presence of factors aggravating its current (small mouth vestibule, vertical incisal disocclusion, close position and position anomalies of some teeth), thus the role of sexual hormones is minimum. Conclusion. There has been established significant correlation of factors aggravating the progress of chronic hypertrophic gingivitis and the level of luteinizing and follicle-stimulating hormones.

Key words: chronic hypertrophic gingivitis, teenagers, hypophysis hormones, sexual hormones.

 

References

  1. Vodolackii, M.P. Harakter i patogenez razvitiya vospalitel’nogo processa v tkanyah parodonta u detei / M.P. Vodolackii, A.A. Pavlov, A.A. Nekrasova // Medicinskii vestnik Severnogo Kavkaza. — 2011. — № 4. — S.18—20.
  2. Grinin, V.M. Kolebaniya gormonal’nogo fona i vliyanie ih na techenie zabolevanii parodonta u zhenschin / V.M. Grinin, A.V. Vinnichenko, Sh.Z. Ataeva // Stomatologiya. — 2012. — № 1. — S.76—78.
  3. Esayan, Z.V. Zabolevaniya parodonta v period polovogo sozrevaniya: epidemiologiya i patogenez / Z.V. Esayan // Vestnik hirurgii Armenii. — 2002. — № 5. — S.3—16.
  4. Zorina, O.A. Mikrobiocenoz polosti rta v norme i pri vospalitel’nyh zabolevaniyah parodonta / O.A. Zorina, A.A. Kulakov, A.I. Grudyanov // Stomatologiya. — 2011. — № 1. — S.73—78.
  5. Lepehina, O.A. Rasprostranennost’ i osobennosti kliniches- kogo techeniya gingivitov u shkol’nikov goroda Voronezha v razlichnye vozrastnye periody: avtoref. dis. ... kand. med. nauk / O.A. Lepehina. — Voronezh, 2011. — 24 s.
  6. Struktura zabolevanii parodonta, vyyavlennyh na terapevticheskom stomatologicheskom prieme / K.I. Ashurov, V.M. Grinin, R.T. Bulyakov [i dr.] // Rossiiskii stomatologicheskii zhurnal. — 2012. — № 2. — S.46—47.
  7. Bacterial and salivary biomarkers predict the gingival in flammatoryprofile / A. Lee, C.B. Ghaname, T.M. Braun [et al.] // J. Periodontol. — 2012. — Vol. 83, № 1. — P.79—89.
  8. Chronic gingivitis: theprevalence of periodont opathogensand therapy efficiency / M. Igic, L. Kesic, V. Lekovic [et al.] // Eur. J. Clin. Microbiol. Infect. Dis. — 2012. — Vol. 31, № 8. — Р.1911—1915.
  9. Hormonal effect on gingiva: pubertal gingivitis / T.R. Chaitra, N. Manuja, A.A. Sinha, A.U. Kulkarni // BMJ Case Rep. — 2012. — Vol. 27. — P.19—23.
  10. Masamatti, S.S. Periodontal diseases in children and adolescents: a clinician’s perspective part / S.S. Masamatti, A. Kumar, M.S. Virdi // Dent. Update. — 2012. — Vol. 39, № 8. — Р.541—544.
  11. Oral health-related perceptions, attitudes, and behavior in relation to oral hygiene conditions in an adolescent population / J.S. Ericsson, A.L. Östberg, J.L. Wennström, K.H. Abrahamsson // Eur. J. Oral. Sci. — 2012. — Vol. 120, № 4. — P.335—341.
  12. Relationship between gingivitis severity, caries experience and orthodontic anomalies in 13—15 year-old adolescents in Brno, Czech Republic / M. Kukletova, L. Izakovicova-Holla, K. Musilova [et al.] // Community Dent Health. — 2012. — Vol. 29, № 2. — Р.179—183.
  13. The level of matrix metalloproteinases and type IV collagen in the gingival mucosa under different clinical forms of periodontitis in pre-and pubertal periods and their prognostic value / Z.G. Tsagareli, T.E. Shishniashvili, L.E. Gogiashvili [et al.] // Georgian. Med. News. — 2012. — Vol. 206. — P.25.

 

PDF downloadResearch of the dynamic occlusion of the pationts with periodontal desease

Rezeda F. Mustakimova, graduate student of prostodontic cathedra, dentistry faculty of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, Kazan, Russia, tel. 8-927-429-49-85, e-mail: rezda@list.ru

GuLshat T. Saleeva, MD, Head of the of prostodontic cathedra, dentistry faculty of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, Kazan, Russia, tel. 8-927-429-49-85, e-mail: rin-gul@mail.ru

Abstract. Aim. Research evaluated premature contacts of patients with periodontal diseases. We considered the following parameters: the mobility of the teeth, pressure of contacts, prioritize contacting teeth Under our observation were 35 patients. We are divided them into 2 groups. In the first group were 10 patients without periodontal disease. In the second — 25 patients with periodontitis . Results. It was revealed that occlusion control of patients with periodontitis, could not find out premature contacts in static occlusion, because of the teeth mobility. Conclusion. Patients with periodontal disease needs correction of premature contacts not only in static occlusion, but also in dynamic occlusion.

Key words: periodontal disease, occlusion.

 

References

  1. Alekseenko, G.V. Klinika, lechenie i aspekty profilaktiki parodontita u bol’nyh nevrasteniei: avtoref. dis. ... kand. med. nauk / G.V. Alekseenko. — Kiev, 1986. — 20 s.
  2. Baevskii, R.I. Prognozirovanie na grani normy i patologii / R.I. Baevskii. — M., 1979. — 295 s.
  3. Bodneva, C.L. Kompleksnaya ocenka faktorov riska pri generalizovannom parodontite: avtoref. dis. ... kand. med. nauk / C.L. Bodneva. — M., 2002. — 24 s.
  4. Borovskii, E.V. Terapevticheskaya stomatologiya / E.V. Borovskii, Yu.D. Barysheva, Yu.M. Maksimovskii. — M.: Medicina, 1998. — 560 s.
  5. Kopeikin, V.N. Rukovodstvo po ortopedicheskoi stomatologii / V.N. Kopeikin [I dr.]; pod red. V.N. Kopeikina. — M.: Medicina, 1993. — 471 s.
  6. Hovat, A.P. Okklyuziya i patologiya okklyuzii / A.P. Hovat, N. Dzhei Kapp, N.V. Dzhei Barrett. — M.; SPb.; Kiev; Almaty; Vil’nyus: Azbuka, 2005. — 235 s.
  7. Glickman, I. Inflammation and trauma from occlusion, co-destructive factors in periodontal disease / I. Glickman // J. Periodontol. — 1963. — Vol. 34. — P.5—10.
  8. Lindhe, J. The influence of trauma from occlusion on the reduced but healthy periodontal tissues in dogs / J. Lindhe, I. Ericsson // J. Clin. Periodontol. — 1976. — Vol. 3. —P.110—122.

 

PDF downloadСlinical and radiological evaluation of jaw bone augmentation according to the CONE-BEAM CT

Gulshat T. Saleeva, MD, Head of Department of Prosthodontics of SBEI HPE «Kazan State Medical University», Russian Ministry of Health, Kazan, Russia, tel. 8-917-393-48-68, e-mail: rin-gul@mail.ru

Zulfiya I. Yarulina, PhD, Assistant Professor Department of Prosthodontics of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, Kazan, Russia, tel. 8-950-311-30-29, e-mail: zulfia.yarulina@yandex.ru

Yuri G. Sedov, Assistant Professor Department of General Dentistry of SBEI HPE «Russian University of Peoples’ Friendship» of Russian Ministry of Education and Science, Moscow, Russia, tel. 8-925-773-34-84, e-mail: sedov135@gmail.com

Pavel N. Mikhalev, PhD, Assistant Professor Department of Prosthodontics of SBEI HPE «Kazan State Medical University» of Russian Ministry of Health, Kazan, Russia, tel. 8-917-393-49-79, e-mail: mihalevpn@mail.ru

Abstract. Aim. The purpose of the study was to analyze the results of the alveolar bone augmentation according to the cone-beam computed tomography. Material and methods. Under our observation were 49 patients aged 28 to 62 years, who had undergone bone-plastic intervention on the upper and lower jaws. Sinus lift with delayed implantation was performed to 20 patients with vertical alveolar bone atrophy of the upper jaw with a residual height of less than 4 mm. Alveolar bone augmentation by GBR was made to 29 patients with mixed or horizontal atrophy. Results. Bone regeneration criteria were formulated according to the clinical data and the results of X-ray examination of patients. Conclusion. Cone-beam computed tomography allowed to give a precise specification and objective criteria of bone regeneration and to adjust the treatment plan.

Key words: dental implantation, jaw bone augmentation, cone-beam computer tomography.

 

References

  1. Garafutdinov, D.M. Eksperimental’no-klinicheskoe obosnovanie vybora metodov luchevoi diagnostiki v klinike dental’noi implantologii: avtoref. dis. ... d-ra med. nauk / D.M. Garafutdinov. — M., 2010. — 28 s.
  2. Kulakov, A.A. Zubnaya implantaciya: osnovnye principy, sovremennye dostizheniya / A.A. Kulakov, F.F. Losev, R.SH. Gvetadze. — M.: OOO «Medicinskoe informacionnoe agentstvo», 2006. — 152 s.
  3. Mirgazizov, A.M. Poisk morfofunkcional’nogo i esteticheskogo optimuma pri planirovanii lecheniya s primeneniem vnutrikostnyh implantatov / A.M. Mirgazizov, M.Z. Mirgazizov, R.M. Mirgazizov // Rossiiskii vestnik dental’noi implantologii. — 2004. — № 3/4(7/8). — S.28—33.
  4. Long-term evaluation of osseointegrated implants placed in sites augmented with sinus floor elevation associated with vertical ridge augmentation: A retrospective study of 38 consecutive implants with 1- to 7-year follow-up / M. Simion [et al.] // Int. J. Periodontics Restorative Dent. — 2004. — № 24. — Р.208—221.
  5. Misch, C.E. Early crestal bone loss etiology and its effective treatment planning for implants / C.E. Misch // Post. Graduate Dent. — 1995. — Vol. 2. — P.3—17.

 

PDF downloadInfluence of trimetazidine МR (Tridukard) on chronic ischemic heart disease

Nail B. Amirov, Nikolay A. Tsibulkin, Anastasia A. Morozova, Elvira B. Frolova, Guzel A. Muhametshina, Olga J. Mihoparova, Olga B. Oschepkova

Abstract. The purpose of the study. Assess the impact of drug metabolic therapy with trimetazidine modified release (Tridukard) for a chronic ischemic heart disease (IHD) when it is included in the scheme of standard therapy (antithrombotics, beta-blockers, lipid-lowering drugs, nitrates, ACE inhibitors). Material and methods. The study involved patients with chronic ischemic heart disease, in some cases, combine with postinfarction cardiosclerosis and heart rhythm disturbances, under the supervision of a clinical hospital NFM Russian Ministry of Internal Affairs in the Republic of Tatarstan. Evaluation of the results of therapy was performed according to the clinical examination, including laboratory and instrumental methods: echocardiography, Holter ECG monitoring and tests with 6-minute walk test. Results. Treatment with trimetazidine MB 35 mg 2 times a day for 4 months as part of standard therapy resulted in a reduction of symptoms of CHD, increased exercise tolerance, based on the results of the sample with a 6-minute walk test, was anti-ischemic and anti-arrhythmic effect on the results of Holter monitoring.

Key words: chronic ischemic heart disease, metabolic therapy, trimetazidine, echocardiography, holter monitoring ECG, test with 6-minute walk.

 

References

  1. Oganov, R.G. Strategii profilaktiki serdechno-sosudistyh zabolevanii v Rossiiskoi Federacii / R.G. Oganov, G.YA. Maslennikova // Klinicheskaya medicina. — 2012. — № 3. — S.4—7.
  2. Nacional’nye rekomendacii po diagnostike i lecheniyu stabil’noi stenokardii // Kardiovaskulyarnaya terapiya i profilaktika. — 2008. — № 7(6). — Pril. 4.
  3. Metelica, V.I. Spravochnik po klinicheskoi farmakologii serdechno-sosudistyh sredstv / V.I. Metelica. — M.: Medpraktika, 1996. — 784 s.
  4. Okorokov, A.N. Lechenie boleznei vnutrennih organov. Lechenie zabolevanii serdechno-sosudistoi sistemy / A.N. Okorokov. — Mn.: Vyshaya shkola, 1997. — T. 3, kn. 1. — 464 s.
  5. Federal’noe rukovodstvo po ispol’zovaniyu lekarstvennyh sredstv (formulyarnaya sistema) / pod red. A.G. CHuchalina, Yu.B. Belousova, V.V. Yasnecova. — M.: OOF «Zdorov’e cheloveka», 2008. — Vyp. IX. — 998 s.
  6. Klinicheskie rekomendacii. Farmakologicheskii spravochnik / pod red. I.A. Denisova, Yu.L. SHevchenko. — M.: GEOTAR-Med, 2004. — 1184 s.

 

PDF downloadComparison of the effectiveness of articaine local anaesthesia for pulpotomy mandibular primary molars

Tatyana Yu. Shiryak, PhD, assistant of department of children’s stomatology of Kazan State Medical University of Russian Ministry of Нealth, Kazan, Russia, tel. 8-904-660-95-24, e-mail: tanya_shiryak@mail.ru

Rinat A. Saleev, MD, professor of department of orthopedic stomatology of Kazan State Medical University of Russian Ministry of Нealth, Kazan, Russia , tel. 8-987-297-88-54, e-mail: rin-gul@mail.ru

Marsel G. Gilyaziev, PhD, assistant of department of children’s stomatology of Kazan State Medical University of Russian Ministry of Нealth, Kazan, Russia, tel. 8-905-375-08-32

Dina M. Mustaeva, ordinator of department of children’s stomatology of Kazan State Medical University of Russian Ministry of Нealth, Kazan, Russia, tel. 8-906-323-73-81

Abstract. Aim.Analyzed the effectiveness of different anaesthetic techniques in the mandible primary teeth. Material and methods. In 180 children aged 3—9 years was189 injections for 207 teeth: inferior alveolar nerve block for 81 teeth (63 injections), mandibular infiltration for 44 primary molars children up to 7 years, and intraseptal injection for 82 primary molars. Used 4% articaine with 1:200 000 epinephrine. Dental procedure included pulpectomies in primary molars. Results.Inferior alveolar nerve blockwas effective in 77,77%, mandibular infiltration in children under 7 years in 61,36%, intraseptal injection was effective in 70,73%. In other cases we had to resort to additional injection, which resulted in a generally positiveresult was obtained in 96,29% of cases. No statistically significant difference was found between the three anaesthetic techniques.

Key words: local analgesia, pulpitis, primary molars, mandible, children, pulpоtomy.

 

References

  1. Vassmanova, E.V. Osobennosti mestnogo obezbolivaniya u detei / E.V. Vassmanova, E.N. Anisimova, E.V. Zoryan [i dr.] // Stomatologiya. — 1996. — № 6. — S.44—49.
  2. D’yakova, S.V. Stomatologiya detskaya. Hirurgiya / S.V. D’yakova. — M.: Medicina, 2009. — 384 s.
  3. Kazakova, L.N. Optimizaciya anesteziologicheskogo posobiya pri lechenii kariesa i ego oslozhnenii u detei: avtoref. dis. ... kand. med. nauk / L.N. Kazakova. — Volgograd, 2005. — 23 s.
  4. Makeeva, I.M. Sravnitel’naya ocenka dopolnitel’nyh mestnyh metodov obezbolivaniya pri ostrom pul’pite / I.M. Makeeva, A.I. Erohin, V.V. Voronkova, A.V. Kuzin // Maestro stomatologii. — № 46. — S.92—96.
  5. Persin, L.I. Stomatologiya detskogo vozrasta / L.I. Persin, V.M. Elizarova S.V. D’yakova. — 5-e izd., pererab. i dop. — M.: Medicina, 2003. — 640 s.
  6. Arrow, P. A comparison of articaine 4% and lignocaine 2% in block and infiltration analgesia in children / P. Arrow // Australian Dental Journal. —2012. — Vol. 7. — Р.1834—1838.
  7. Ashkenazi, M. Effectiveness of computerized delivery of intrasulcular anesthetic in primarymolars / M. Ashkenazi, S. Blumer, I. Eli //Am. Dent. Assoc. — 2005. — Vol. 136(10). — Р.1418—1425.
  8. Daggal, M.S. Lechenie i restavraciya molochnyh zubov / M.S. Daggal, M.E.Dzh. Kerzon, S.A. Feil [i dr.]; per. s angl.; pod red. prof. T.F. Vinogradovoi. — M.: MEDpress-inform, 2006. — 160 s.
  9. Dudkiewicz, A. Effectiveness of mandibular infiltration in children using the local anesthetic Ultracaine / A. Dudkiewicz, S. Schwartz, R. Laliberte // J. Canad. Dent. Assoc. — 1987. — Vol. 1(53). — P.29—31.
  10. Malamed, S.F. Local anesthetic considerations in dental specialties / S.F. Malamed // Handbook of Local Anesthesia. — 5th ed. — P.269.
  11. Oulis, C. The effectiveness of mandibular infiltration compared to mandibular block anesthesia in treating primary molars in children / C. Oulis, G. Vadiakas, A. Vasilopoulou // Pediatr. Dent. — 1996. — Vol. 18, № 4. — P.301—305.
  12. Yassen, G. H. Evaluation of mandibular infiltration versus mandibular block anaesthesia in treating primary canines in children / G.H. Yassen // Int. J. Paediatr. Dent. — 2010. — Vol. 20, № 1. — P.43—49.
  13. Schwartz, S. Local Anesthesia in Pediatric Dentistry. Continuing Education Units. Crest® Oral-B® at dentalcare.com / S. Schwartz // Continuing Education Course. — 2012. — 31 р.

 

PDF downloadThe improved method of determining bile acids in serum by gas-liquid chromatography

Zukhra Sh. Minnullina, postgraduate student of the Departament of therapy of SBEI APE «Kazan State Medical Academy» of Russian Ministry of Health, Kazan, Russia, tel. 8-919-641-77-00, e-mail: zukhra-minnullina@yandex.ru

Abstract. Aim. Evaluation of efficacy, safety and functional method of determining informativeness of bile acids in serum by gas-liquid chromatography. Material and methods. To determine the content of bile acids has been selected by gas-liquid chromatography. The effectiveness of this method is shown by the example of determination of cholic, deoxycholic, ursodeoxycholic, chenodeoxycholic acids having diagnostic value. The uniqueness of this method lies in the fact that for the first time will be shown in the chromatogram relationship qualitative and quantitative composition of bile acids in the blood with clinical manifestations of hepatobiliary tract pathology. Results. Based on the processing of chromatograms calculated relative correction factors of methyl esters of bile acids. The resultant chromatograms were evaluated by the method of internal standardization. Determined by the primary bile acids, such as cholic, chenodeoxycholic and secondary bile acids: deoxycholic and ursodeoxycholic. Their ratio in the blood serum of control subjects averaged 1:1:0,8:0,2 (0,67 mg%:0,66 mg%:0,44 mg%:0,33mg%). Gender and age did not affect the content of bile acids. The total amount of bile acids averaged (1,66±0,27) mg%. Conclusion. Determination of the main bile acids in serum by gas-liquid chromatography is sufficiently accurate, minimally invasive and informative. Represented a direct correlation between the qualitative and quantitative composition of bile acids in the serum with the development of the clinical picture, which would enable earlier diagnosis of diseases.

Key words: GLC, bile acids: cholic, chenodeoxycholic, deoxycholic, cholic acid methyl esters, bile acid conjugates.

 

References

  1. Bogomolov, P.O. Steatoz pecheni i nealkogol’nyi steato- gepatit / P.O. Bogomolov, Yu.O. Shul’pekova // Bolezni pecheni i zhelchevyvodyaschih putei / pod red. V.T. Ivashkina. — 2-e izd. — 2005. — S.205—216.
  2. Ivashkin, V.T. Klinicheskaya gepatologiya segodnya i zav- tra / V.T. Ivashkin, A.O. Bueverov // Rossiiskii zhurnal gastrologii, gepatologii, koloproktologii. — 2002. — № 1. — S.4—9.
  3. Ilyushina, T.V. Diagnosticheskie vozmozhnosti luchevyh metodov issledovaniya v vyyavlenii zhirovoi distrofii pecheni / T.V. Ilyushina, V.A. Ratnikov, A.N. Kovalev [i dr.] // Eksperimental’naya i klinicheskaya gastroenterologiya. — 2004. — № 1. — C.79—80.
  4. Isakov, V.A. Statiny i pechen’: druz’ya ili vragi? / V.A. Isakov // Klinicheskaya gastroenterologiya i gepatologiya. — 2008. — T. 1, № 5. — S.372—374.
  5. Klinicheskie perspektivy v gastroenterologii, gepatologii. — 2010. — № 3. — S.12—15.
  6. Lazebnik, L.B. Aterogennaya dislipidemiya i insulino- rezistentnost’, associirovannye s nealkogol’noi zhirovoi bolezn’yu pecheni (shodstva i razlichiya), differencirovannyi podhod k terapii / L.B. Lazebnik, L.A. Zvenigorodskaya, N.V. Mel’nikova [i dr.] // Kardiovaskulyarnaya terapiya i profilaktika. — 2009. — № 3. — S.69—77.
  7. Mizandari, M.T. Kompleksnaya luchevaya diagnostika diffuznoi patologii pecheni (zhirovoi gepatoz, hronicheskii gepatit, cirroz) / M.T. Mizandari, A.S. Mtvaradze, O.U. Urushadze [i dr.] // Medicinskaya vizualizaciya. — 2009. — № 1. — S.60—65.
  8. Severov, M.N. Biopsiya pecheni: celesoobraznost’, protivo- pokazaniya i oslozhneniya / M.N. Severov, E.R. Namestnikov, V.A. Rameev // Vrach. — 2008. — № 10. — S.36—38.
  9. Homeriki, S.G. Klinicheskaya morfologiya pecheni po materialam punkcionnyh biopsii v CNIIG za poslednie 10 let / S.G. Homeriki, S.D. Shepeleva // Eksperimental’naya i klinicheskaya gastroenterologiya. — 2007. — № 1. — S.136.
  10. Sherlok, Sh.D. Zabolevaniya pecheni i zhelchnyh putei: per. s angl. / Sh.D. Sherlok. — M., 2002. — S.425—426.
  11. Yakovenko, E.P. Metabolicheskie zabolevaniya pe- cheni: nealkogol’nyi steatoz i steatogepatit. Diagnostika i lechenie / E.P. Yakovenko, N.A. Agafonova, V.P. Grigor’eva [i dr.] // Kachestvo zhizni. Medicina. — 2004. — № 2(5). — S.55.
  12. Kichian, K. Nonalcoholic fatty liver disease in patients investigated for elevated liver enzymes / K. Kichian, L.M. Gramlich, V.G. Bain [et al.] // Clin. and Invest. Med. — 2009. — Vol. 4. — P.199—200.
  13. Lefkowitch, J.H. Hepatobiliary pathology / J.H. Lefkowitch // Curr. Opin. Gastroenterol. — 2006. — Vol. 19. — P.185—193.
  14. Moseley, R.H. Liver and biliary tract / R.H. Moseley // Curr. Opin. Gastroenterol. — 2007. — Vol. 19. — P.181—184.

 

PDF downloadPrimary sensitivity to antibacterials among Helicobacter pylori isolates from patients with chronic gastritisis and gastroduodenitis

Adel O. Pozdeeva, Lidiya G. Morozova, Oskar K. Pozdeev, Alexander O. Pozdnyak

Abstract. Aim. The sensitivity to antibacterials among the H.pylori strains isolated from gastric and duoudenal mucous membranes has been studied. Material and methods. 70 patients were examined. 46 patients had gastritis, 24 patients had gastroduodenitis among them. Results. The low rate of resistance to clarithromycin, amoxicillin, ciprofloxacin, tetracycline, furozalidone and high resistance to metronidazole were established. Result was compared to data on resistance in Europe.

Key words: Helicobacter pylori, gastritis, gastroduodenitis, resistance, antibacterials.

 

References

  1. Boyanova, L. Prevalence of multidrug-resistant Helicobacter pylori in Bulgaria / Boyanova L. // J. Med. Microbiol. — 2009. — Vol.58, рt 7. — P.930—935.
  2. O'Connor, A. Treatment of Helicobacter pylori infection 2013 / A. O'Connor, J. Molina-Infante, J.P. Gisbert, C. O'Morain // Helicobacter. — 2013. — Vol. 18, suppl. 1. — P.58—65.
  3. Sierra, F. Commentary: overcoming antibiotic resistance with Helicobacter pylori therapy-optimisation is the way forward; authors' reply / F. Sierra, J.D. Forero, M. Rey, [et al.] // Aliment. Pharmacol. Ther. — 2013. — Vol. 38, № 2. — P.205—206.
  4. Boyanova, L. Prevalence and evolution of Helicobacter pylori resistance to 6 antibacterial agents over 12 years and correlation between susceptibility testing methods / L. Boyanova, G. Gergova, R. Nikolov [et al.] // Diagn. Microbiol. Infect. Dis. — 2008. — Vol. 60, № 2. — P.409—415.
  5. Cui, R. Helicobacter pylori infection: an overview in 2013, focus on therapy / R. Cui, L. Zhou // Chin. Med. J. (Engl). — 2014. — Vol. 127, № 3. — P.568—573.
  6. Selgrad, M. Guidelines for treatment of Helicobacter pylori in the East and West / M. Selgrad, J. Bornschein, P. Malfertheiner // Expert Rev. Anti. Infect. Ther. — 2011. — Vol. 9, № 8. — P.581—588.
  7. Ierardi, E. How antibiotic resistances could change Helicobacter pylori treatment: A matter of geography? / E. Ierardi, F. Giorgio, G. Losurdo [et al.] // World J. Gastroenterol. — 2013. — Vol. 19, № 45. — P.8168—8180.
  8. Mégraud, F. H.pylori antibiotic resistance: prevalence, importance, and advances in testing / F. Mégraud // Gut. — 2004. — Vol. 53, № 9. — P.1374—1384.
  9. De Francesco, V. Worldwide H.pylori antibiotic resistance: a systematic review / V. De Francesco, F. Giorgio, C. Hassan [et al.]// J. Gastrointestin Liver Dis. — 2010. — Vol. 19, № 4 — P.409—414.
  10. Glupczynski, Y. European multicenter survey of in vitro antimicrobial resistance in Helicobacter pylori / Y. Glupczynski, F. Megroud, M. Lopez-Brea, L.P. Andersen // Eur. J. Clin. Microbiol. Infect. Dis. — 2001. — Vol. 20, № 11. — P.820—823.
  11. Megraud, F. Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption / F. Megraud, S. Coenen, A. Versporten [et al.] // Gut. — 2013. — Vol. 62, № 1. — P.34—42.
  12. Siavoshi, F. Increase in resistance rates of H.pylori isolates to metronidazole and tetracycline. Comparison of three 3-year studies / F. Siavoshi, P. Saniee, S. Latifi-Navid [et al.]// Arch. Iran. Med. — 2010. — Vol. 13, № 3. — P.177—187.
  13. Graham, D.Y. Furazolidone in Helicobacter pylori therapy: misunderstood and often unfairly maligned drug told in a story of French bread / D.Y. Graham, H. Lu // Saudi J. Gastroenterol. — 2012. — Vol. 18, № 1. — P.1—2.
  14. Duck, W.M. Antimicrobial resistance incidence and risk factors among Helicobacter pylori-infected persons, United States / W.M. Duck, J. Sobel, J.M. Pruckler [et al.] // Emerg. Infect. Dis. — 2004. — Vol. 10, № 6. — P.1088—1094.
  15. Prechtl, J. Monitoring of antibiotic resistance rates of Helicobacter pylori in Austrian children, 2002—2009 / J. Prechtl, A. Deutschmann, T. Savic [et al.] // Pediatr. Infect. Dis. J. — 2012. — Vol. 31, № 3. — P.312—324.
  16. Li, S. Meta-analysis of randomized controlled trials on the efficacy of probiotics in Helicobacter pylorieradication therapy in children / S. Li, X.L. Huang, J.Z. Sui [et al.] // Eur. J. Pediatr. — 2014 — Vol. 173, № 2. — P.153—161.
  17. Du, Y.Q. Adjuvant probiotics improve the eradication effect of triple therapy for Helicobacter pyloriinfection / Y.Q. Du, T. Su, J.G. Fan [et al.] // World J. Gastroenterol. — 2012 — Vol. 18, № 43. — P.6302—6307.
  18. Cukanov, V.V. Sovremennye aspekty eradikacii Helicobacter pylori /. V.V. Cukanov, O.S. Amel'chugova, N.N. Butorin [i dr.] // Terapevticheskii arhiv. — 2013. — T. 85, № 2. — S.73—75.
  19. Starostin, B.D. Ekspress-metod diagnostiki inficirovannosti Campylobacter pylori zheludka i dvenadcatiperstnoi kishki / B.D. Starostin, A.V. Petrutik // Klinicheskaya medicina. — 1989. — T. 67, № 8. — S.50—52.
  20. Kudryavceva, L.V. Dinamika rezistentnosti shtammov нelikobakter pilori k amoksicillinu, klaritromicinu i metronidazolu v Roscii v 1996—2001 gg. / L.V. Kudryavceva // Pediatriya. — 2002. — № 2 (pril.). — S.63—64.

 

HELP FOR PRACTITIONER

PDF downloadPsychiatrist and expert in narcology. The legislation during realization of preliminary and periodic medical examinations

Svetlana V. Kuzmina, PhD, assistant of the Department of psychiatry sub-faculty with narcology course of SBEI HPE «Kazan State Medical University» of Russia Ministry of Health, Kazan, Russia, tel. 8-987-296-22-49, e-mail: skouzmina21@list.ru

Abstract. Follow to the importance of mental health of population, and especially among working people, the interrelation of legislations were analyzed. In article we gave criteria of general and special medical condition of mental health with which workers are not allowed to begin or continue their job. We gave the model of mental health examination follow the Russian Federation low in health.This model could be used by psychiatrists during preventive and periodical health examination among workers which professions are mentioned in the list of Injunction of MH of RF N-302н. We show the role of the occupational pathologist and staff-administration in process of medical examination of workers.

Key words: periodical, prevention, mental health examination, mental status, Injunction of MH of RF N-302н.

 

References

  1. Psihicheskoe zdorov'e: usilenie bor'by s psihicheskimi rasstroistvami // Informacionnyi byulleten' VOZ. — 2012. — № 220.
  2. Houtman, I.D. Rabota i psihicheskoe zdorov’e / I.D. Houtman, M.J. Kompier. — URL: http://base.safework.ru/
  3. Prikaz Minzdravsocrazvitiya Rossii ot 12.04.2011 № 302n «Ob utverzhdenii perechnei vrednyh i (ili) opasnyh proizvodstvennyh faktorov i rabot, pri vypolnenii kotoryh provodyatsya obyazatel’nye predvaritel’nye i periodicheskie medicinskie osmotry (obsledovaniya), i Poryadka provedeniya obyazatel’nyh predvaritel’nyh i periodicheskih medicinskih osmotrov (obsledovanii) rabotnikov, zanyatyh na tyazhelyh rabotah i na rabotah s vrednymi i (ili) opasnymi usloviyami truda». — URL: http://base.consultant.ru/cons/cgi/online.cgi?req=doc;base=LAW;n=30618
  4. Federal’nyi zakon ot 21.11.2011 № 323-FZ «Ob osnovah ohrany zdorov’ya grazhdan v RF».
  5. Trudovoi kodeks Rossiiskoi Federacii. Federal’nyi zakon ot 30.12.2001 № 197.
  6. Zakon RF ot 02.07.1992 №3185-1 «O psihiatricheskoi pomoschi i garantiyah prav grazhdan pri ee okazanii».
  7. Postanovlenie Soveta ministrov — Pravitel’stva RF ot 28.04.1993 № 377 “O realizacii Zakona Rossiiskoi Federacii «O psihiatricheskoi pomoschi i garantiyah prav grazhdan pri ee okazanii» (s izmeneniyami ot 23 maya, 31 iyulya 1998 g., 21 iyulya 2000 g., 8 maya, 23 sentyabrya 2002 g.)». — URL: http://base.garant.ru/4102003/
  8. Postanovlenie Pravitel’stva RF ot 23.09.2002 № 695 «O prohozhdenii obyazatel’nogo psihiatricheskogo osvidetel’stvovaniya rabotnikami, osuschestvlyayuschimi otdel’nye vidy deyatel’nosti, v tom chisle deyatel’nost’, svyazannuyu s povyshennym istochnikom opasnosti (s vliyaniem vrednyh veschestv i neblagopriyatnyh proizvodstvennyh faktorov), a takzhe rabotayuschih v usloviyah povyshennoi opasnosti».
  9. Postanovlenie Pravitel’stva RF ot 18.05.2011 № 394 «Ob utverzhdenii perechnya otdel’nyh vidov professional’noi deyatel’nosti i deyatel’nosti, svyazannoi s istochnikom povyshennoi opasnosti, na zanyatie kotorymi ustanavlivayutsya ogranicheniya dlya bol’nyh narkomaniei».

 

PDF downloadPreliminary clinical and laboratory stages of management of bruxism

Gulshat T. Saleeva, MD, Head of the Department of Prosthetics of SBEI HPE «Kazan State Medical University», Kazan, Russia, e-mail: rin-gul@mail.ru

Ildar I. Sagitov, аssistant of the Department of Prosthetics of SBEI HPE «Kazan State Medical University», Kazan, Russia, e-mail: sagitov@me.com

Laisan R. Saleeva, student of SBEI HPE «Kazan State Medical University», Kazan, Russia

Dina B. Valieva, dentist of dental policlinic of SBEI HPE «Kazan State Medical University», Kazan, Russia

Abstract. At present there exists a large variety of materials and methods for rehabilitation of patients with defects of teeth hard tissues. However, at present the problem of the construction longevity is still actual. One of the causes of the construction failure may be bruxism. Prevalence of bruxism according to different authors varies from 6—20%. The reason why it is so variable is the frequent lack of information for patients about the given pathology and the difficulty of its identification at early stages. Aim. To show possibilities of a temporary prosthetic repair at complex dental treatment. Material and methods. In this article some preliminary stages are described concerning the management of patients of bruxism before prosthesis with permanent constructions. Results. At treatment of patients with bruxism use temporary constructions as the intermediate stage, is necessary and does treatment of patients with this pathology more predictable.

Key words: bruxism, centric relation, axiography, electromyography, deprogrammer.

 

References

  1. Koyano, K. Assessment of bruxism in the clinic / K. Koyano, Y. Tsukiyama, R. Ichiki, T. Kuwata // J. Oral. Rehabil. — 2008.
  2. Lang, R. Treatment of bruxism in individuals with develop- mental disabilities: a systematic review / R. Lang, P.J. White, W. Machalicek [et al.] // Res. Dev. Disabil. — 2009.
  3. Macedo, C.R. Occlusal splints for treating sleep bruxism (tooth grinding) / C.R. Macedo, A.B. Silva, M.A. Machado [et al.] // Cochrane Database Syst. Rev. — 2007.
  4. Nassar, M. S. The effect of a Lucia jig for 30 minutes on neuromuscular re-programming, in normal subjects / M.S. Nassar, M. Palinkas, S.C. Regalo [et al.] // Braz. Oral. Res. — 2012.
  5. Tan, E.K. Variability and validity of polymorphism association studies in Parkinson’s disease / E.K. Tan, M. Khajavi, J.I. Thornby [et al.] // Neurology. — 2000.
  6. Williamson, E.H. Anterior guidance: its effect on electro- myographic activity of the temporal and masseter muscles / E.H. Williamson, D.O. Lundquist // J. Prosthet. Dent. — 1983.

 

PDF downloadApplication of soft chewing test at the electromyography of chewing muscles

Margarita A. Belousova, PhD, associate professor, Leading researcher of functional research method Laboratory of moscow State university of medicine and Dentistry of russian ministry of Health, moscow, russia, tel. 8-916-308-32-98, e-mail: mabelousova@mail.ru

Aida D. Goncharenko, PhD, associate professor of the Department of Periodontology Moscow State University of Medicine and Dentistry of Russian Ministry of Health, Moscow, Russia, tel. 8-916-619-49-52, e-mail: adgoncharenko@mail.ru

Sergey N. Ermolev, MD, professor, Head of the functional research method laboratory of moscow State university of Medicine and Dentistry of Russian Ministry of Health, Moscow, Russia, tel. 8-915-330-97-68, e-mail: esn54@mail.ru

Nina K. Loginova, MD, professor, leading researcher of functional research method laboratory of moscow State university of Medicine and Dentistry of Russian Ministry of Health, Moscow, Russia, tel. 8-903-963-94-93, e-mail: profloginova_nk@mail.ru

Abstract. Aim.The purpose of our scientific work was development an electromyographic investigation of masticatory muscles by electromyography (EMG) with soft chewing testin patients with mobility of teeth with periodontal disease and during orthodontic treatment. Material and methods. Under our observation were 32 patients. We are divided them into 2 groups. In the first group were 17 patients aged 35—44 years with moderate periodontitis. In the second — 15 patients aged 18—22 years during active orthodontic treatment. Comparison of two types of chewing test (filbert nut and kernels of cedar nut) is carried out. Results and discussion.When used for chewing test filbert as the test material (traditional chewing test) revealed: increase of the maximum values of the EMG amplitudes of massetersto (39,0±2,9)% (p<0,05), increase of asymmetry coefficientof masseterwork in average to 5—11% in patients of both groups. Conclusion.Our proposed highly informativemethod estimates the electromyographic activity of masticatory muscles by electromyography (EMG) in patients with mobility of teeth with periodontal disease and during orthodontic treatment is based on the use of physiological soft chewing test (10 kernels of cedar).

Key words: soft chewing test, masticatory muscles, electromyography (EMG).

 

References

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  10. Sverzut, C.E. Effect of surgically assisted rapid maxillary expansion on masticatory muscle activity: A pilot study / C.E. Sverzut, K. Martorelli, R. Jabur [et al.] // Ann. Maxilofac. Surg. — 2011. — Vol. 1, № 1. — P.32—36.

 

PDF downloadMycobacterium tuberculosis drug resistance forming during the course of TB treatment. Realities of domestic TB management program and medical aspects of drug resistant TB epidemic prevention (part 2)

Arkady L. Khanin, Sergey A. Dolgikh, Irina B. Viktorova

Abstract. In addressing MDR-TB, and thus increase the effectiveness of treatment and the possibility of establishing control of the TB epidemic the best option is a set of activities that combines the positive aspects of WHO’s approaches/IACAT and domestic phthisiology. Rational to limit the amount of DR-TB treatment centers with the use of drugs in the reserve only TB facilities with modern medical-diagnostic equipment, trained medical and nursing staff, while providing social support for patients and informal control the conduct of treatment (WHO/MSTBL). In modern conditions, needs and experiences of domestic phthisiology comprising an individual approach to the patient with the use of inpatient, outpatient, spa treatments, use of physical therapy, and surgical techniques. Developed algorithmic system of selection and treatment for drug resistant TB patients minimizes the risk of drug resistance amplification during the course of TB treatment.

Key words: drug-resistant tuberculosis; treatment organization.

 

References

  1. Borisov, S.E. Etiotropnoe lechenie tuberkuleza pri lekarstven- noi ustoichivosti MBT. Vzglyady i rekomendacii mezhduna- rodnyh organizacii / S.E. Borisov, G.B. Sokolova // Consilium medicum. — 2001. — T. 3, № 12. — S.595—602.
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  8. Rabochee soveschanie veduschih ftiziatrov Rossii «Rol’ i mesto ftorhinolonov v lechenii bol’nyh tuberkulezom» // Problemy tuberkuleza. — 2008. — № 8. — S.38—42.
  9. Rider, G.L. Epidemiologicheskie osnovy bor’by s tuberkulezom: per. s angl. / G.L. Rider. — M.: Ves’ mir, 2001. — 192 s.
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  13. Hanin, A.L. Problema lekarstvenno-ustoichivogo tuberkuleza. Vozmozhnye puti resheniya na primere krupnogo promyshlennogo goroda Sibiri / A.L. Hanin, S.A. Dolgih, I.B. Viktorova // Vestnik sovremennoi klinicheskoi mediciny. — 2011. — № 1. — S.9—17.
  14. Towards universal access to diagnosis and treatment of multidrug-resistant and extensively drug-resistant tuberculosis by 2015: WHO progress report 2011. — WHO/HTM/TB/2011.3. — 119 p. — URL: http://whqlibdoc.who.int/publications/2011/9789241501330_eng.pdf

 

CASE FROM PRACTICE

PDF downloadClinical example of the effectiveness of antibacterial therapy with sarcoidosis skin

Maria V. Listopadova, the assistant of the Department of Phthisiopulmonology of SBEI HPE «Smolensk State Medical Academy» of Russian Ministry of Health, Smolensk, Russia, tel. 8-950-705-26-76, e-mail: listopadovamasha@mail.ru

Alexander A. Punin, MD, Head of the Department of Faculty Therapy of SBEI HPE «Smolensk State Medical Academy» of Russian Ministry of Health, Smolensk, Russia, tel. 8(4812) 27-11-06, e-mail: 001e316@mail.ru

Aleksei Yu. Kuzmenkov, the student of SBEI HPE «Smolensk State Medical Academy» of Russian Ministry of Health, Smolensk, Russia, tel. 8-908-283-55-99, e-mail: kuzmenkov111@mail.ru

Abstract. Aim. Describe complex clinical case of sarcoidosis of the skin and provide a discussion on the treatment strategy for this patient. Material and methods. A retrospective case histories studied archives patient with severe skin sarcoidosis, analyzed clinical, laboratory and instrumental changes during the observation period and demonstrated the entire sequence of the treatment. Talk. The case of sarcoidosis presented with skin ineffective prolonged systemic glucocorticoid therapy. On the background of a course of ceftriaxone marked a clear positive dynamics of skin changes. Whether this fact is associated with pro-inflammatory activity of the drug or its effect on the infectious «trigger» for this patient remains unclear. Conclusion. A more profound study of infectious triggers in the development of sarcoidosis.

Key words: sarcoidosis scin, antibacterial therapy.

 

References

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  3. David, R. Moller State of the Art. Potential Etiologic Agents in Sarcoidosis / R. David // Proceedings of the American Thoracic Society. — 2007. — Vol. 4 (5). — P.465—468.
  4. Ishige, I. Quantitative PCR of mycobacterial and pro- pionibacterial DNA in lymph nodes of Japanese patients with sarcoidosis / I. Ishige, Y. Usui, T. Takemura, Y. Eishi // Lancet. — 1999. —Vol. 354 (9173). — P.120—123.
  5. Kalfin, E. Experimental Skin Sarcoidosis In A Doctor Volunteer / E. Kalfin // The Internet Journal of Internal Medicine. — 2004. — Vol. 5 (1).
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  7. Khan, A.A. Effect of clarithromycin and azithromycin on production of cytokines by human monocytes / A.A. Khan, T.R. Slifer, F.G. Araujo, J.S. Remington // Int. J. Antimicrob Agents. — 1999. — Vol. 11 (2). — P.121—132.
  8. Yamasawa, H. Macrolides inhibit epithelial cell-mediated neutrophil survival by modulating granulocyte macrophage colony-stimulating factor release / H. Yamasawa, K. Oshikawa, S. Ohno, Y. Sugiyama // Am. J. Respir. Cell. Mol. Biol. — 2004. — Vol. 30 (4). — P.569—575.
  9. Marshall, T.G. Sarcoidosis succumbs to antibiotics- implications for autoimmune disease / T.G. Marshall, F.E. Marshall // Autoimmun. Rev. — 2004. — Vol. 3 (4). — P.295—300.
  10. Marino, W.D. Combined Pentoxifylline and Doxycycline as A Steroid-Sparing Adjuvant Regimen In Sarcoidosis / W.D. Marino // Chest Meeting Abstracts. — 2008. — Vol. 134. — P.62004.

 

EXPERIMENTAL MEDICINE TO APPLIED HEALTHCARE

PDF downloadAntihypoxic activity of 6-aryl-4-hydroxy-5,6-dihydro-4h-1,3-oxazines

Svetlana S. Zykova, PhD (Pharm), associate professor of chair zootechnology of the FSEI HPE «Federal Penitentiary Service Institute of Russia», Perm, Russia, tel. 8-909-731-09-74, e-mail: zykova.sv@rambler.ru

Abstract. The purpose of research — find connections among 6-arylsubstituted-benzoilatsetil-4-hydroxy-5,6-dihydro-4H-1,3-oxazines with antihypoxic activity. Materials and Methods.Antihypoxic activity studied seven 6-aryl-substituted-4-benzoilatsetil-4-hydroxy-5,6-dihydro-4H-1,3-oxazine, obtained by reacting 1,6-diaryl-3,4-dihydroxy-2,4-hexadiene-1,6-dione with multiple Schiff bases. On two models of hypoxia — hypercapnia with normobaric and hemic — studied antihypoxic synthesized compounds. As a comparison drug used modern antioxidant and antihypoxant «Meksidol». Results and discussion. Assessment antihypoxic actions performed over time to increase life expectancy of mice under conditions of acute hypoxia. The synthesized compounds showed moderate and high antihypoxic activity.

Кеy words: oxazines, antihypoxic activity, normobaric hypoxia, hemic hypoxia, mexidol.

 

References

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  2. Shirinkina, S.S. Vzaimodeistvie 1,3,4,6-tetrakarbonil'nyh soedinenii s arilidenarilaminami / S.S. Shirinkina, N.M. Igidov, V.O. Koz'minyh / Materialy YUbileinoi mezhvuz. nauch.-prakt. konf. prof.-prep. sostava, posvyasch. 275-letiyu goroda Permi i 80-letiyu farm. obrazovaniya na Urale. — Perm', 1998. — S.62—63.
  3. Kulinskii, V.I. Aktivnye formy kisloroda i oksidativnaya modifikaciya makromolekul: pol'za, vred i zaschita / V.I. Kulinskii // Sorosovskii obrazovatel'nyi zhurnal. — 1999. — № 1. — S.2—7.
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  9. Maevskii, E.I. Korrekciya metabolicheskogo acidoza putem podderzhaniya funkcii mitohondrii / E.I. Maevskii. — Puschino: ITEBF RAN, 2001. — 155 s.